The Influence of Particulate Matter on Respiratory Morbidity and Mortality in Children and Infants.

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The Influence of Particulate Matter on Respiratory Morbidity and Mortality in Children and Infants.

Adv Exp Med Biol. 2014 Nov 9;

Authors: Jakubiak-Lasocka J, Lasocki J, Badyda AJ

Abstract
Air pollution is the most important environmental health risk leading to premature mortality, respiratory and other health problems. The aim of this study was to quantify its impact on infants and children in Warsaw (Poland), following the principles of Health Impact Assessment method. Particulate matter (PM2.5 and PM10) was considered as the indicator of air pollution. Exposure-response functions between air pollution and health impacts were employed based on the literature. According to the calculations, around 5,201 asthma symptoms and 234 hospital respiratory admissions were caused annually due to air pollution. Hospitalizations due to cardiovascular problems related to air pollution amounted to 13. The mortality among infants and children is relatively low and occurs mostly in the postneonatal period. Nonetheless, approx. 5 mortality cases were assessed to be air pollution-attributable. The study demonstrates a significant impact of air pollution on infants and children, which is manifested primarily as a range of respiratory problems.

PMID: 25381559 [PubMed – as supplied by publisher]

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Variation in the Management of Infants Hospitalized for Bronchiolitis Persists after the 2006 American Academy of Pediatrics Bronchiolitis Guidelines.

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Variation in the Management of Infants Hospitalized for Bronchiolitis Persists after the 2006 American Academy of Pediatrics Bronchiolitis Guidelines.

J Pediatr. 2014 Jul 8;

Authors: Florin TA, Byczkowski T, Ruddy RM, Zorc JJ, Test M, Shah SS

Abstract
OBJECTIVE: To describe variation across US pediatric hospitals in the utilization of resources not recommended for routine use by the American Academy of Pediatrics guideline for infants hospitalized with bronchiolitis and to examine the association between resource utilization and disposition outcomes.
STUDY DESIGN: We conducted a cross-sectional study of infants ?12 months hospitalized for bronchiolitis from 2007-2012 at 42 hospitals contributing data to the Pediatric Health Information System. Patients with asthma were excluded. The primary outcome was hospital-level variation in utilization of 5 resources not recommended for routine use: albuterol, racemic epinephrine, corticosteroids, chest radiography, and antibiotics. We also examined the association of resource utilization with length of stay (LOS) and readmission.
RESULTS: In total, 64?994 hospitalizations were analyzed. After adjustment for patient characteristics, albuterol (median, 52.4%; range, 3.5%-81%), racemic epinephrine (20.1%; 0.6%-78.8%), and chest radiography (54.9%; 24.1%-76.7%) had the greatest variation across hospitals. Utilization of albuterol, racemic epinephrine, and antibiotics did not change significantly over time compared with small decreases in corticosteroid (3.3%) and chest radiography (8.6%) use over the study period. Utilization of each resource was significantly associated with increased LOS without concomitant decreased odds of readmission.
CONCLUSIONS: Substantial use and variation in 5 resources not recommended for routine use by the American Academy of Pediatrics bronchiolitis guideline persists with increased utilization associated with increased LOS without the benefit of decreased readmission. Future work should focus on developing processes that can be widely disseminated and easily implemented to minimize unwarranted practice variation when evidence and guidelines exist.

PMID: 25015578 [PubMed – as supplied by publisher]

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Asthma rates lower in infants exposed to dander and droppings – Mother Nature Network (blog)


Mother Nature Network (blog)

Asthma rates lower in infants exposed to dander and droppings
Mother Nature Network (blog)
They not only found that infants exposed to some of these specific bacteria have much less chance of getting asthma later in life, but they also found that those exposed to all three allergens (pet, mouse and cockroach) had even less chance of getting

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Dirtier’ Homes Lower Asthma Risk In Infants During Their First Year Of Life – Medical Daily

Dirtier' Homes Lower Asthma Risk In Infants During Their First Year Of Life
Medical Daily
The evidence suggests that early exposure to a range of bacteria and allergens during the first year of life was associated with lower asthma rates. However, greater exposure to those same pathogens during the course of the first three years of life

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Lower Asthma Risk Linked To Microbes In Infants’ Homes – Counsel & Heal


Counsel & Heal

Lower Asthma Risk Linked To Microbes In Infants' Homes
Counsel & Heal
Infants who are exposed to a diverse range of bacterial species in house dust during the first year of life are less likely to develop asthma in early childhood, according to a new study. (Photo : Flickr/ Joe Shlabotnik). Infants who are exposed to a
Microbes in homes may lower asthma risk in infantsAuthint Mail

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Lower Asthma Risk Is Associated with Microbes in Infants’ Homes – UCSF News Services


Latin Post

Lower Asthma Risk Is Associated with Microbes in Infants' Homes
UCSF News Services
Infants exposed to a diverse range of bacterial species in house dust during the first year of life appear to be less likely to develop asthma in early childhood, according to a new study published online on June 6, 2014, in the Journal of Allergy and
Children Benefit From Early Exposure to Bacteria and Allergens: StudyLatin Post
Early Exposure to Certain Bacteria May Protect Toddlers From WheezingInfection Control Today

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Giving antibiotics to infants may make them more prone to asthma, study says – Washington Post

Giving antibiotics to infants may make them more prone to asthma, study says
Washington Post
By age 3, about 18 percent of the children had developed wheezing or asthma. Compared with those who had never taken antibiotics, children who had taken the medication in infancy were twice as likely to have developed wheezing and 60 percent more …

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Low gut microbial diversity in infants’ intestines can increase risk for asthma – News-Medical.net

Low gut microbial diversity in infants' intestines can increase risk for asthma
News-Medical.net
Low gut microbial diversity in the intestines of infants can increase the risk for asthma development. These are the findings of the age 7 follow-up in a multi-year study led by researchers at Linköping University in Sweden. In 2011 the results of a 

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