UCSF Highlights a Need for More Precision Medicine Research in Underserved Populations University of California San Francisco researchers report that the largest-ever whole-genome sequencing study of drug response in minority children has revealed new clues about why the front-line asthma…
Asthma Flare-ups in Children
Short-term increases in inhaled steroid doses do not prevent asthma flare-ups in children NIH-funded findings challenge common practice of increasing doses at early signs of worsening symptoms. Researchers have found that temporarily increasing the dosage of inhaled steroids when asthma…
Patient, Physician, and Health-System Factors Influencing the Quality of Antidepressant and Sedative Prescribing for Older, Community-Dwelling Adults.
Related Articles Patient, Physician, and Health-System Factors Influencing the Quality of Antidepressant and Sedative Prescribing for Older, Community-Dwelling Adults. Health Serv Res. 2016 Dec 26;: Authors: Extavour RM, Perri M Abstract OBJECTIVE: To identify determinants of potentially inappropriate (PI) antidepressant…
Ponciretin attenuates ethanol-induced gastric damage in mice by inhibiting inflammatory responses.
Related Articles Ponciretin attenuates ethanol-induced gastric damage in mice by inhibiting inflammatory responses. Int Immunopharmacol. 2016 Dec 22;43:179-186 Authors: Kang GD, Kim DH Abstract BACKGROUND: Poncirin (PO) and isosakuranetin (or ponciretin [PT]) are compounds found in fruits of the genus…
Ventilation/perfusion ratio and right to left shunt in healthy newborn infants.
Related Articles Ventilation/perfusion ratio and right to left shunt in healthy newborn infants. J Clin Monit Comput. 2016 Dec 23;: Authors: Dassios T, Ali K, Rossor T, Greenough A Abstract Oxygenation impairment can be assessed non-invasively by determining the degree…
Interventions To Help Asthma Clinical Adherence
Conditions: Asthma/Drug Therapy; Medication Adherence/Statistics & Numerical Data; Reminder Systems; Humans; Hispanic Americans; Communication Barriers; ChildInterventions: Device: SmartInhaler with reminder function turned on; Device: SmartInhalerSponsors: University of California, San Francisco; Academic Pediatric AssociationNot yet recruiting – verified December 2016 View full post on ClinicalTrials.gov:…
Treatment of asthma: predicting the future of atopic disease treatment Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 2.
Related Articles Treatment of asthma: predicting the future of atopic disease treatment Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 2. Pol Arch Med Wewn. 2016 Dec 23;126(12):1031-1032 Authors: O’Byrne P, Jaeschke R PMID: 28010009 [PubMed – in process]…
Study of Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REGN3500 in Adults With Moderate Asthma
Conditions: Asthma; Moderate AsthmaInterventions: Drug: REGN3500; Drug: PlaceboSponsors: Regeneron Pharmaceuticals; SanofiNot yet recruiting – verified December 2016 View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Allergic Sensitization at School Age is a Systemic Low-grade Inflammatory Disorder.
Related Articles Allergic Sensitization at School Age is a Systemic Low-grade Inflammatory Disorder. Allergy. 2016 Dec 19;: Authors: Chawes BL, Stokholm J, Schoos AM, Rahman N, Brix S, Bisgaard H Abstract BACKGROUND: Systemic low-grade inflammation has been demonstrated in a…
Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies.
Related Articles Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies. Front Pharmacol. 2016;7:299 Authors: Thompson MD, Capra V, Clunes MT, Rovati GE, Stankova J, Maj MC, Duffy DL Abstract Genetic variants…