Nebulized Magnesium Sulfate as an Adjunct to Standard Therapy in Asthma Exacerbation

Condition:   Asthma
Interventions:   Drug: Nebulized Magnesium Sulfate;   Drug: Nebulized isotonic saline;   Drug: Nebulized Salbutamol;   Drug: Ipratropium bromide;   Drug: Methylprednisolone or Prednisolone
Sponsor:   Hospital General Naval de Alta Especialidad
Recruiting – verified October 2015

View full post on ClinicalTrials.gov: asthma | received in the last 14 days

Evaluation of Dupilumab’s Effects on Airway Inflammation in Patients With Asthma

Condition:   Asthma
Interventions:   Drug: dupilumab SAR231893/REGN668;   Drug: placebo;   Drug: fluticasone propionate and salmeterol;   Drug: budesonide and formoterol;   Drug: mometasone furoate and formoterol
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Not yet recruiting – verified October 2015

View full post on ClinicalTrials.gov: asthma | received in the last 14 days

Two-part Safety, Tolerability, Pharmacodynamic and -Kinetic Study of Inhaled AZD8871 in Asthmatic and COPD Subjects

Conditions:   Asthma (Part 1);   COPD (Part 2)
Interventions:   Drug: Dose 1, AZD8871 50 ?g (Part 1);   Drug: Dose 2, AZD8871 100 ?g (Part 1);   Drug: Dose 3, AZD8871 300 ?g (Part 1);   Drug: Dose 4, AZD8871 600 µg (Part 1);   Drug: Dose 5, AZD8871 1200 µg (Part 1);   Drug: Dose 6, AZD8871 1800 ?g (Part 1);   Drug: Placebo, AZD8871 placebo (Part 1);   Drug: Treatment A, AZD8871 dose A (Part 2);   Drug: Treatment B, AZD8871 dose B (Part 2);   Drug: Treatment C, Indacaterol 150 ?g (Part 2);   Drug: Treatment D, Tiotropium 18 ?g (Part 2)
Sponsor:   AstraZeneca
Not yet recruiting – verified October 2015

View full post on ClinicalTrials.gov: asthma | received in the last 14 days

Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma

Condition:   Asthma
Interventions:   Device: T-Piece Nebulizer;   Device: Breath-Enhanced Nebulizer;   Drug: Albuterol;   Procedure: Pre-Treatment Spirometry Measurement;   Procedure: Post-Treatment Spirometry Measurement
Sponsors:   Seton Healthcare Family;   University of Texas
Not yet recruiting – verified September 2015

View full post on ClinicalTrials.gov: asthma | received in the last 14 days