Key insights for Asthmatics: Makes Asthma Worse Significant Association with Exacerbations Among this panel of relatively moderate to severe asthmatics, the respiratory irritants produced by several domestic combustion sources were associated with increased morbidity. Although there is abundant clinical evidence…
Asthma and Gut Health
The gut and lungs are anatomically distinct, but potential anatomic communications and complex pathways involving their respective microbiota have reinforced the existence of a gut–lung axis (GLA). Compared to the better-studied gut microbiota, the lung microbiota, only considered in recent…
Why Cell Biology of Asthma Matters
Cell types responsible for the major pathology in asthma: 1. Epithelial cells – initiate airway inflammation mucus, and 2. Smooth muscle cells – contract excessively to cause airway narrowing. The clinical manifestations of asthma are caused by obstruction of the…
Aspirin Exacerbated Respiratory Disease
What is aspirin-exacerbated respiratory disease (AERD) Aspirin-exacerbated respiratory disease (AERD) is a clinical tetrad of nasal polyps, chronic hypertrophic eosinophilic sinusitis, asthma and sensitivity to any medication that inhibits cyclooxygenase-1 (COX-1) enzymes, namely aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)…
Learn About Biomarkers in Asthma and Why they Matter
Asthma is a heterogenous disease characterized by multiple phenotypes driven by different mechanisms. The implementation of precision medicine in the management of asthma requires the identification of phenotype-specific markers measurable in biological fluids. To become useful, these biomarkers need to…
Asthma’s Inner World – a patients journey of discovery
By Alan Gray World Asthma Foundation (WAF) is supporting care of Asthma and asthmatics around the world through a new Severe Asthma Series focused on “Defeating Asthma” with the aim of shining a spotlight on a deeper understanding and getting…
Defeating Asthma Series Announced for World Asthma Day, May 5, 2020
World Asthma Foundation is supporting care of Asthma and asthmatics around the world through a new series focused on Defeating Asthma with the aim of shining a spotlight on getting to a cure The World Asthma Foundation (WAF) exists…