Conditions: Asthma; Healthy
Intervention:
Sponsors: University of Michigan; National Institutes of Health (NIH)
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Conditions: Asthma; Healthy
Intervention:
Sponsors: University of Michigan; National Institutes of Health (NIH)
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Persistent Asthma
Intervention: Procedure: Bronchoscopy
Sponsors: University of Leicester; Genentech, Inc.; Queen’s University, Belfast; Medical Research Council
Not yet recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Related Articles |
Asthma and cesarean delivery.
J Pediatr. 2016 Sep;176:221-4
Authors: Schooling CM
PMID: 27568254 [PubMed – in process]
View full post on pubmed: asthma
Related Articles |
Can we prevent Childhood Asthma Before Birth?: Summary of the VDAART results so far.
Expert Rev Respir Med. 2016 Aug 26;
Authors: Weiss ST, Litonjua AA
PMID: 27564842 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Asthma
Interventions: Drug: Salbutamol; Procedure: Forced oscillation technique; Procedure: Plethysmography
Sponsor: Central Hospital, Nancy, France
Completed – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Predictive Properties of the Asthma Control Test and Its Component Questions for Severe Asthma Exacerbations.
J Allergy Clin Immunol Pract. 2016 Aug 17;
Authors: Cajigal S, Wells KE, Peterson EL, Ahmedani BK, Yang JJ, Kumar R, Burchard EG, Williams LK
Abstract
BACKGROUND: Current US guidelines recommend the Asthma Control Test (ACT) for assessing disease control and selecting treatment.
OBJECTIVE: The goal of this study was to prospectively assess the ACT and its component questions for their utility in predicting the risk of severe asthma exacerbations.
METHODS: Individuals were participants in the Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity, and those included in the current analysis had the following characteristics: age 18 years or more, physician-diagnosed asthma, and longitudinal care received at a large health system in southeastern Michigan. Study participants underwent a baseline evaluation, which included answering the ACT. A severe asthma exacerbation was defined as one requiring oral steroids, an emergency department visit, or inpatient admission. Receiver-operator characteristic curves were used to measure and compare the predictive utility of the ACT and its component questions for severe asthma exacerbations.
RESULTS: Of 1180 participants, 354 (30.0%) experienced a severe asthma exacerbation within 6 months of their baseline evaluation. When compared with the individual questions that composed the ACT, the composite score was significantly better at predicting severe exacerbations with 1 exception; the composite ACT score and the question assessing rescue medication use were not significantly different (P = .580). Pharmacy-based records of metered-dose inhaler short-acting beta-agonist use and asthma severity were also not significantly different from the composite ACT score.
CONCLUSIONS: Our study demonstrates that although the ACT is modestly predictive for exacerbations, the composite score may not be superior to assessing rescue medication use alone for predicting the risk of severe asthma exacerbations.
PMID: 27544712 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Management and referral of patients with severe and poorly controlled asthma in primary care.
Fam Pract. 2016 Aug 20;
Authors: Orozco-Beltrán D, Carratalá-Munuera C, Arriero JM, Campo P, Martínez-Moragón E, Molina J, Quintano-Jiménez JA, Gil-Guillén VF, Working Group for the Consensus Document on the Management of Severe Asthma in Adults in Primary Health Care
Abstract
BACKGROUND: Over 50% of treated patients with asthma in Europe are not well controlled. Their management in primary health care (PHC) differs from that in specialized care, and there is no real coordination between the two.
OBJECTIVES: To identify barriers and solutions to improving the management of patients with severe and poorly controlled asthma and the communication between specialists and PHC, and to reach a consensus on the criteria for referral patients.
METHODS: An observational study using a modified Delphi technique. About 79 physicians from PHC, pneumology and allergy fields from different Spanish regions were invited to participate via an online questionnaire. Consensus was reached on an item when more than two-thirds of the panel members scored within the 3-point category (1-3 or 7-9) containing the median and the interquartile range of answers had to be ?4 points.
RESULTS: Response rate: 52%. After the second round, consensus items were 40 (62.5%): of which 37 in agreement and 3 in disagreement. Around 92.68% of respondents agreed that it would be useful to incorporate questionnaires for asthma control into PHC computer-based searches. About 100% of participants agreed that clear consensus criteria between PHC and specialists must be determined to decide when a patient with asthma is referred from PHC to specialist or vice versa. Ten of the proposed criteria reached consensus agreement.
CONCLUSION: The failure to use guidelines and specific questionnaires for asthma control in PHC is one reason why there is underdiagnosis and poor control of asthma. Some strategies to improve the asthma care management emerged from the survey results.
PMID: 27543792 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Conditions: Bronchial Asthma; Cytokines
Intervention:
Sponsor: Taipei Veterans General Hospital, Taiwan
Recruiting – verified March 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Asthma
Interventions: Drug: Benralizumab; Other: Placebo
Sponsor: AstraZeneca
Not yet recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: COPD
Intervention: Other: No intervention
Sponsor: Chinese University of Hong Kong
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days