High Frequency Chest Wall Oscillation for asthma and chronic obstructive … – 7thSpace Interactive (press release)

High Frequency Chest Wall Oscillation for asthma and chronic obstructive
7thSpace Interactive (press release)
The objective of this study was to evaluate the use of HFCWO early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD). Methods: Randomized, multi-center, double-masked phase II clinical trial of

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Treatment of allergic asthma: Modulation of Th2 cells and their responses – 7thSpace Interactive (press release)

Treatment of allergic asthma: Modulation of Th2 cells and their responses
7thSpace Interactive (press release)
Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory response in the airways. It is currently treated and, more or less,

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Adult attention deficit hyperactivity disorder is associated with asthma – 7thSpace Interactive (press release)

Adult attention deficit hyperactivity disorder is associated with asthma
7thSpace Interactive (press release)
Similarly, asthma also has a substantial prevalence among adults. Previous studies concerning a potential relationship between ADHD and asthma have not presented consistent results. Methods: A cross-sectional study of 594 adult patients diagnosed with

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Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta … – 7thSpace Interactive (press release)

Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta
7thSpace Interactive (press release)
Asthma is a phenotypically diverse disease with genetic susceptibility. A single nucleotide polymorphism (SNP) in the CD14 gene at position -260 (also known as -159) C>T has been inconsistently associated with asthma. The aim of this study was to

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The asthma candidate gene NPSR1 mediates isoform specific downstream signalling – 7thSpace Interactive (press release)

The asthma candidate gene NPSR1 mediates isoform specific downstream signalling
7thSpace Interactive (press release)
Neuropeptide S Receptor 1 (NPSR1, GPRA, GPR154) was first identified as an asthma candidate gene through positional cloning and has since been replicated as an asthma and allergy susceptibility gene in several independent association studies.

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In vivo imaging of the airway wall in asthma: Fibered confocal fluorescence … – 7thSpace Interactive (press release)

In vivo imaging of the airway wall in asthma: Fibered confocal fluorescence
7thSpace Interactive (press release)
Airway remodelling is a feature of asthma including fragmentation of elastic fibres observed in the superficial elastin network of the airway wall. Fibered confocal fluorescence microscopy (FCFM) is a new and non-invasive imaging technique performed

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Altered expression of microRNA in the airway wall in chronic asthma: miR-126 … – 7thSpace Interactive (press release)

Altered expression of microRNA in the airway wall in chronic asthma: miR-126
7thSpace Interactive (press release)
In a mouse model, we have previously shown that miRNAs are potentially important therapeutic targets in allergic asthma, because inhibition of miR-126, one of a small subset of miRNAs upregulated in the airway wall, effectively suppressed Th2-driven

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(Correcting) misdiagnoses of asthma: a cost effectiveness analysis – 7thSpace Interactive (press release)

(Correcting) misdiagnoses of asthma: a cost effectiveness analysis
7thSpace Interactive (press release)
The prevalence of physician-diagnosed-asthma has risen over the past three decades and misdiagnosis of asthma is potentially common. Objective: to determine whether a secondary-screening-program to establish a correct diagnosis of asthma in those who

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Asthma exacerbation and proximity of residence to major roads: a population … – 7thSpace Interactive (press release)

Asthma exacerbation and proximity of residence to major roads: a population
7thSpace Interactive (press release)
The relationship between asthma and traffic-related pollutants has received considerable attention. The use of individual-level exposure measures, such as residence location or proximity to emission sources, may avoid ecological biases.

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