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Asthma study aided by Pitt, Allegheny Health eyes acetaminophen link
Tribune-Review “I don't think the entire asthma epidemic is due to Tylenol. But I think it may have significantly contributed,” said McBride, a vice chairman at Akron Children's Hospital in Ohio who found “incredible consistency” in reported patterns of acetaminophen … |
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Asthma study aided by Pitt, Allegheny Health Network eyes acetaminophen link
Tribune-Review But I think it may have significantly contributed,” said McBride, a vice chairman at Akron Children's Hospital in Ohio who found “incredible consistency” in reported patterns of acetaminophen use and bad asthma symptoms. “I just think it's important … |
View full post on asthma – Google News
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Is Acetaminophen, AKA Tylenol, Causing Asthma Rise?
WebProNews On Monday, The Daily Mail reported that children who were given liquid Paracetamol for pain relief, in the form of a drink such as Calpol, just once a month were five times as likely to develop asthma as children not given paracetamol. For those of us … |
View full post on asthma – Google News
 Medscape |
The Association Between Acetaminophen and Asthma – Medscape
Medscape During the last few decades, a huge epidemiological effort has been made all over the world in order to cast some light on the origin of asthma (or 'wheezing disorders' as a general term) and its recent increase in prevalence. The focus on genetic … |
View full post on asthma – Google News
| Related Articles |
Prescription-Acquired Acetaminophen Use and the Risk of Asthma in Adults: A Case-Control Study (December).
Ann Pharmacother. 2012 Nov 20;
Authors: Kelkar M, Cleves MA, Foster HR, Hogan WR, James LP, Martin BC
Abstract
BACKGROUND:Studies have examined the association between acetaminophen use and asthma; however, their interpretation is limited by several methodologic issues.OBJECTIVE:To investigate the association between recent and chronic prescription-acquired acetaminophen use and asthma.METHODS:This retrospective case-control study used a 10% random sample of the IMS LifeLink commercial claims data from 1997 to 2009. Cases had to have at least 1 incident claim of asthma; 3:1 controls matched on age, sex, and region were randomly chosen. Acetaminophen exposure, dose, and duration were measured in the 7- and 30-day (recent) and the 1-year (chronic) look-back periods. Multivariable conditional logistic regression was used to estimate the risk of asthma associated with acetaminophen use adjusted for comorbidities, other drugs increasing asthma risk, and health system factors.RESULTS:There were 28,892 cases and 86,676 controls, with mean age of 42.8 years; 37.7% were males, and 22.6% of cases and 18.2% of controls had acetaminophen exposure in the pre-index year, with mean cumulative doses of 78.7 g and 59.8 g, respectively. There was no significant association between recent prescription acetaminophen exposure and asthma (7 days: OR 1.02, p = 0.74; 30 days: OR 0.97, p = 0.38). Cumulative prescription acetaminophen dose in the year prior increased asthma risk compared to acetaminophen nonusers (?1 kg: OR 1.09, p < 0.001 and >1 kg: OR = 1.60, p = 0.02). Duration of prescription acetaminophen use greater than 30 days was associated with elevated asthma risk (OR 1.39, p < 0.001).CONCLUSIONS:Chronic prescription-acquired acetaminophen use was associated with an increased risk of asthma, while recent use was not. However, over-the-counter acetaminophen use was not captured in this study and further epidemiologic research with complete acetaminophen exposure ascertainment and research on pathophysiologic mechanisms is needed to confirm these relationships.
PMID: 23170033 [PubMed – as supplied by publisher]
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 Mother Nature Network (blog) |
Acetaminophen Could Raise Asthma Risk In Infants, Study Concludes
RedOrbit Findings reported in the Journal of Allergy and Clinical Immunology showed that babies given acetaminophen for pain and fever may have an increased risk of asthma symptoms. The Danish study included 336 children who were followed from birth to age … Acetaminophen in infancy again tied to asthma, study suggests Calpol, forms of paracetamol likely to develop asthma in children Acetaminophen linked to asthma in babies |
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 The Malaysian Insider |
Acetaminophen in infancy again tied to asthma, study suggests
Fox News "We think it is too early to conclude a causal relationship," he told Reuters Health in an email – though he added that the findings should encourage further research into a "plausible biological mechanism" by which acetaminophen could promote asthma. Acetaminophen in infancy again tied to asthma: Study |
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Acetaminophen in infancy again tied to asthma: study
Reuters "We think it is too early to conclude a causal relationship," he told Reuters Health in an email – though he added that the findings should encourage further research into a "plausible biological mechanism" by which acetaminophen could promote asthma. |
View full post on asthma – Google News
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Acetaminophen in infancy again tied to asthma
Chicago Tribune The findings, from a study of 411 Danish children, add to a mixed bag of research into whether there's a link between acetaminophen – better known by the brand-name Tylenol – and kids' asthma risk. Researchers found that the more acetaminophen kids … |
View full post on asthma – Google News
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Acetaminophen in infancy again tied to asthma
Reuters The findings, from a study of 411 Danish children, add to a mixed bag of research into whether there's a link between acetaminophen – better known by the brand-name Tylenol – and kids' asthma risk. Researchers found that the more acetaminophen kids … |
View full post on asthma – Google News