Breathe Well Live Well
Condition: Asthma
Intervention: Dietary Supplement: coconut oil
Sponsors: Brigham and Women’s Hospital; Harvard School of Public Health
Not yet recruiting – verified June 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Kinetics of omega-3 polyunsaturated fatty acids when co-administered with saturated or omega-6 fats.
Metabolism. 2015 Aug 28;
Authors: Dias CB, Wood LG, Phang M, Garg ML
Abstract
OBJECTIVE: Absorption of long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) has been shown to be potentiated when consumed with a high fat meal. However, the effect of different dietary fats on n-3PUFA absorption and postprandial kinetics has not been previously studied.
METHOD: In a randomized cross-over design intervention, postprandial incorporation of LCn-3PUFA into plasma lipids following consumption of a meal rich in either saturated fat or omega-6 polyunsaturated fatty acids (n-6PUFA) was investigated. Healthy adult male and female subjects (n=26) were fed an isocaloric meal containing equivalent amount of either butter or sunflower seed oil supplemented with 1.8grams of LCn-3PUFA (300mg eicosapentaenoic acid, 20:5n-3 and 1500mg docosahexaenoic acid, 22:6n-3).
RESULTS: Postprandial plasma lipids were enriched with saturated fatty acids and linoleic acid (18:2n-6) following consumption of the butter and the sunflower oil containing meals respectively. The increase in plasma 20:5n-3 and 22:6n-3 levels over the 6hour study period was similar in both the saturated and the n-6 fat groups.
CONCLUSION: These results suggest that the expected competition between LCn-3PUFA and n-6PUFA at the absorption level is unlikely; therefore competition at the enzymatic level should be primarily responsible for differences in their metabolic and clinical effects. Trial registered with the Australia New Zealand Trial registry as ACTRN12612000654853.
PMID: 26386693 [PubMed – as supplied by publisher]
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Cow's milk allergy affected fatty acids, asthma risk in children
Healio Serum fatty acid proportions and asthma risk differed between young children with cow's milk allergy and those without, according to study results. Mirka Lumia, MD, a pediatrician and neonatologist, and colleagues asked children in Finland who at aged … |
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Vitamin C, zinc and omega 3 fatty acids may help asthma
Food Consumer Bronchial asthma is caused by chronic inflammation in airways and nutritional intervention is known to decrease the severity of many chronic inflammatory disease including asthma, according to researchers at Mohammed Al Biltagi of Tanta University … |
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Fatty acids may protect infants against allergies
Pediatric SuperSite Ensuring that children receive adequate amounts of omega-3 and omega-6 fatty acids in infancy may help protect against wheezing, asthma and atopic dermatitis during the first few years of life, according to data presented at the 2011 Annual Meeting of … |
View full post on asthma – Google News