Fumes from cleaning products can affect asthma – Las Vegas Review-Journal


Las Vegas Review-Journal

Fumes from cleaning products can affect asthma
Las Vegas Review-Journal
Fumes from cleaning products used at work can make existing asthma worse, according to a new study of professional cleaning service employees. Products such as bleach, glass cleaner, detergents and air fresheners exacerbated asthma-related symptoms …

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Indicators of airborne fungal concentrations in urban homes: Understanding the conditions that affect indoor fungal exposures.

Indicators of airborne fungal concentrations in urban homes: Understanding the conditions that affect indoor fungal exposures.

Sci Total Environ. 2015 Feb 25;517C:113-124

Authors: Crawford JA, Rosenbaum PF, Anagnost SE, Hunt A, Abraham JL

Abstract
Indoor fungal exposure can compromise respiratory health. Low-income urban areas are of concern because of high asthma and allergy rates and housing disrepair. Understanding the conditions that affect indoor fungal exposures is important for assessing health risks and for developing mitigation strategies. We examined the types and concentrations of airborne fungi inside and outside of homes in low-income areas of Syracuse, NY as well as the effect of snow cover on fungal levels. At 103 homes, air samples for viable fungi were collected, occupants were interviewed and homes were inspected for visible mold, musty odors, water problems and other factors. Multivariable logistic regression was used to relate high fungal levels to home conditions. Predominant indoor fungi included Cladosporium, Penicillium, Aspergillus, Alternaria and hyaline unknowns. Basidiomycetes and an uncommon genus Acrodontium were also found frequently due to analysis methods developed for this project. With snow cover, outdoor total fungal levels were depressed and indoor concentrations were three times higher than outdoor on average with a maximum of 29 times higher. Visible mold was related to elevated levels of Penicillium (OR 4.11 95% CI 1.37-14.0) and bacteria (OR 3.79 95% CI 1.41-11.2). Musty, moldy odors were associated with elevated concentrations of total fungi (OR 3.48 95% CI 1.13-11.6) and basidiomycetes. Cockroaches, an indicator of moisture, were associated with elevated levels of Penicillium (OR 3.66 95% CI 1.16-13.1) and Aspergillus (OR 4.36 95% CI 1.60-13.4). Increasing relative humidity was associated with higher concentrations of Penicillium, yeasts and basidiomycetes. Visible mold, musty odors, indoor humidity and cockroaches are modifiable factors that were important determinants of indoor fungal exposures. Indoor air investigators should interpret indoor:outdoor fungal ratios cautiously when snow cover is present.

PMID: 25725196 [PubMed – as supplied by publisher]

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Zinc oxide nanoparticles affect the expression of p53, Ras p21 and JNKs: an ex vivo/in vitro exposure study in respiratory disease patients.

Related Articles

Zinc oxide nanoparticles affect the expression of p53, Ras p21 and JNKs: an ex vivo/in vitro exposure study in respiratory disease patients.

Mutagenesis. 2014 Nov 6;

Authors: Kumar A, Najafzadeh M, Jacob BK, Dhawan A, Anderson D

Abstract
Zinc oxide (ZnO) nanoparticles are the mostly used engineered metal oxide nanoparticles in consumer products. This has increased the likelihood of human exposure to this engineered nanoparticle (ENPs) through different routes. At present, the majority of the studies concerning ZnO ENPs toxicity have been conducted using in vitro and in vivo systems. In this study, for the first time we assessed the effect of ZnO ENPs on the major cellular pathways in the lymphocytes of healthy individuals as well as in susceptible patients suffering from lung cancer, chronic obstructive pulmonary disease (COPD) and asthma. Using the differential expression analysis, we observed a significant (P < 0.05) dose-dependent (10, 20 and 40 µg/ml for 6h) increase in the expression of tumour suppressor protein p53 (40, 60 and 110%); Ras p21 (30, 52 and 80%); c-Jun N-terminal kinases; JNKs) (28, 47 and 78%) in lung cancer patient samples treated with ZnO ENPs compared to healthy controls. A similar trend was also seen in COPD patient samples where a significant (P < 0.05) dose-dependent increase in the expression of tumour suppressor protein p53 (26, 45 and 84%), Ras p21 (21, 40 and 77%), JNKs (17, 32 and 69%) was observed after 6h of ZnO ENPs treatment at the aforesaid concentrations. However, the increase in the expression profile of tested protein was not significant in the asthma patients as compared to controls. Our results reiterate the concern about the safety of ZnO ENPs in consumer products and suggest the need for a complete risk assessment of any new ENPs before its use.

PMID: 25381309 [PubMed – as supplied by publisher]

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Airborne particles beyond traffic fumes may affect asthma risk – Medical Xpress


Delhi Daily News

Airborne particles beyond traffic fumes may affect asthma risk
Medical Xpress
"These effects are likely to contribute to the development of asthma in childhood, as well as to worsening of asthma when pollution levels are high." said Dr. Rakesh Kumar, lead author of the study. "Our findings emphasize that larger airborne
Traffic fume particles aren't asthma triggers, study findsThe Australian
Traffic fume particles do not trigger asthma: StudyDelhi Daily News

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