Asthma drug a potential treatment for aging brains, according to new study – ChristianToday


ChristianToday

Asthma drug a potential treatment for aging brains, according to new study
ChristianToday
A new study has found that a drug originally intended for the management of asthma attacks has been found to rejuvenate the aging brain. The study, conducted by researchers at Paracelsus Medical University in Austria and published in Nature …
Affordable asthma medicine to treat dementiaThe Siasat Daily

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Asthma drug reverses aging in the brain of mice – ZME Science


ZME Science

Asthma drug reverses aging in the brain of mice
ZME Science
Working with mice, the researchers gave some of the elderly rodents a common drug called Montelukast that's used to treat asthma in children. To everyone surprise, the old rats started growing new brain cells and performed almost as well as the young
Asthma drug could rejuvenate ageing brains, study suggestsThe Guardian
Asthma drug found to rejuvenate older rat brainsMedical Xpress
Old rat brains rejuvenated and new neurons grown by asthma drugNew Scientist
Next Big Future –Daily Mail –City A.M.
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Evolution of exhaled nitric oxide levels throughout development and aging of healthy humans.

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Evolution of exhaled nitric oxide levels throughout development and aging of healthy humans.

J Breath Res. 2015;9(3):036005

Authors: Jacinto T, Malinovschi A, Janson C, Fonseca J, Alving K

Abstract
It is not fully understood how the fraction of exhaled nitric oxide (FeNO) varies with age and gender in healthy individuals. We aim to describe the evolution of FeNO with age, giving special regard to the effect of gender, and to relate this evolution to natural changes in the respiratory tract.We studied 3081 subjects from NHANES 2007-08 and 2009-10, aged 6-80?years, with no self-reported diagnosis of asthma, chronic bronchitis or emphysema, and with normal values of blood eosinophils and C-reactive protein. The relationship of the mean values of FeNO to age, in all participants and divided by gender, was computed, and compared with changes in anatomic dead space volume and forced vital capacity. A change-point analysis technique and subsequent piecewise regression was used to detect breakpoints in the evolution of FeNO with age.Three distinct phases in the evolution of FeNO throughout the age range 6-80?years can be seen. FeNO values increase linearly between 6-14?years of age in girls and between 6-16?years of age in boys, in parallel with somatic growth. After that, FeNO levels plateau in both genders until age 45?years in females and age 59?years in males, when they start to increase linearly again. This increase continues until age 80.Our data clearly show a triphasic evolution of FeNO throughout the human age range in healthy individuals. This should be accounted for in development of reference equations for normal FeNO values.

PMID: 25993061 [PubMed – in process]

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National Institute on Aging Funds Research on Asthma in Elderly – Lung Disease News


Lung Disease News

National Institute on Aging Funds Research on Asthma in Elderly
Lung Disease News
Asthma is a chronic inflammatory lung condition that can provoke severe medical complications in patients older than 60 years. The most common symptoms are coughing, wheezing, chest tightness and shortness of breath, but there is little knowledge about …

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