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AlerSense develops world's first smart airborne allergy and asthma early …
News-Medical.net AlerSense Incorporated has created the world's first smart airborne allergy and asthma early warning system alerting consumers as particles and toxins build. AlerSense™ is an in-home unit when, combined with the mobile app, delivers accurate … |
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Classroom airborne endotoxin levels lead to increased asthma symptoms
Healio Inner-city children with asthma are at risk for experiencing more asthma symptoms because of being exposed to high airborne endotoxin levels at school, according to study results. “Our study suggests that if classroom-specific airborne endotoxin levels … |
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Indicators of airborne fungal concentrations in urban homes: Understanding the conditions that affect indoor fungal exposures.
Sci Total Environ. 2015 Feb 25;517C:113-124
Authors: Crawford JA, Rosenbaum PF, Anagnost SE, Hunt A, Abraham JL
Abstract
Indoor fungal exposure can compromise respiratory health. Low-income urban areas are of concern because of high asthma and allergy rates and housing disrepair. Understanding the conditions that affect indoor fungal exposures is important for assessing health risks and for developing mitigation strategies. We examined the types and concentrations of airborne fungi inside and outside of homes in low-income areas of Syracuse, NY as well as the effect of snow cover on fungal levels. At 103 homes, air samples for viable fungi were collected, occupants were interviewed and homes were inspected for visible mold, musty odors, water problems and other factors. Multivariable logistic regression was used to relate high fungal levels to home conditions. Predominant indoor fungi included Cladosporium, Penicillium, Aspergillus, Alternaria and hyaline unknowns. Basidiomycetes and an uncommon genus Acrodontium were also found frequently due to analysis methods developed for this project. With snow cover, outdoor total fungal levels were depressed and indoor concentrations were three times higher than outdoor on average with a maximum of 29 times higher. Visible mold was related to elevated levels of Penicillium (OR 4.11 95% CI 1.37-14.0) and bacteria (OR 3.79 95% CI 1.41-11.2). Musty, moldy odors were associated with elevated concentrations of total fungi (OR 3.48 95% CI 1.13-11.6) and basidiomycetes. Cockroaches, an indicator of moisture, were associated with elevated levels of Penicillium (OR 3.66 95% CI 1.16-13.1) and Aspergillus (OR 4.36 95% CI 1.60-13.4). Increasing relative humidity was associated with higher concentrations of Penicillium, yeasts and basidiomycetes. Visible mold, musty odors, indoor humidity and cockroaches are modifiable factors that were important determinants of indoor fungal exposures. Indoor air investigators should interpret indoor:outdoor fungal ratios cautiously when snow cover is present.
PMID: 25725196 [PubMed – as supplied by publisher]
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Delhi Daily News |
Airborne particles beyond traffic fumes may affect asthma risk
Medical Xpress "These effects are likely to contribute to the development of asthma in childhood, as well as to worsening of asthma when pollution levels are high." said Dr. Rakesh Kumar, lead author of the study. "Our findings emphasize that larger airborne … Traffic fume particles aren't asthma triggers, study finds Traffic fume particles do not trigger asthma: Study |
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New Study Shows Asthma & Allergy Sufferers Can Help Reduce Airborne …
MarketWatch To help reduce exposure to allergy and asthma triggers, many patients implement lifestyle changes, such as washing bedding frequently, using hypo-allergenic pillow cases and HEPA vacuum cleaners, and using high-efficiency air filters in forced heating … |
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IL-33 and Thymic Stromal Lymphopoietin Mediate Immune Pathology in Response to Chronic Airborne Allergen Exposure.
J Immunol. 2014 Jul 11;
Authors: Iijima K, Kobayashi T, Hara K, Kephart GM, Ziegler SF, McKenzie AN, Kita H
Abstract
Humans are frequently exposed to various airborne allergens in the atmospheric environment. These allergens may trigger a complex network of immune responses in the airways, resulting in asthma and other chronic airway diseases. In this study, we investigated the immunological mechanisms involved in the pathological changes induced by chronic exposure to multiple airborne allergens. Naive mice were exposed intranasally to a combination of common airborne allergens, including the house dust mite, Alternaria, and Aspergillus, for up to 8 wk. These allergens acted synergistically and induced robust eosinophilic airway inflammation, specific IgE Ab production, type 2 cytokine response, and airway hyperresponsiveness in 4 wk, followed by airway remodeling in 8 wk. Increased lung infiltration of T cells, B cells, and type 2 innate lymphoid cells was observed. CD4(+) T cells and type 2 innate lymphoid cells contributed to the sources of IL-5 and IL-13, suggesting involvement of both innate and adaptive immunity in this model. The lung levels of IL-33 increased quickly within several hours after allergen exposure and continued to rise throughout the chronic phase of inflammation. Mice deficient in IL-33R (Il1rl1(-/-)) and thymic stromal lymphopoietin receptor (Tslpr(-/-)) showed significant reduction in airway inflammation, IgE Ab levels, and airway hyperresponsiveness. In contrast, mice deficient in IL-25R or IL-1R showed minimal differences as compared with wild-type animals. Thus, chronic exposure to natural airborne allergens triggers a network of innate and adaptive type 2 immune responses and airway pathology, and IL-33 and thymic stromal lymphopoietin most likely play key roles in this process.
PMID: 25015831 [PubMed – as supplied by publisher]
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Research on aero-mycological study to analyse airborne fungal flora
Pakistan Daily Times This study will be helpful to physicians/allergists in devising appropriate treatment and preventive methodologies for their asthma and allergy patients in the city of Karachi. The study says, “Airborne fungal spores are well known to cause respiratory … |
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 Family Practice News Digital Network |
Airborne Pollens and Asthma-Related ED Visits Coincide
Family Practice News Digital Network ORLANDO – Asthma-related visits to emergency departments spike in the spring, when grass and tree pollen levels are at their highest, according to investigators in two separate studies presented here at the annual meeting of the American Academy of … |
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 Columbus Dispatch |
Miserable? Blame airborne pollen
Daytona Beach News-Journal However, if it's windy while pollination is in progress, there exists a higher tendency of wind-borne-pollen induced allergies, including conjunctivitis, rhinitis and asthma. In the United States, most wind-pollinating plants — those not attractive to … Firstborn kids seem to have more food allergies, hay fever Reported pollen counts may be inaccurate, study finds Firstborns more vulnerable to food allergies |
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