Louisville ranked fourth worst city for allergies by Asthma and Allergy Foundation of America – WDRB


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Louisville ranked fourth worst city for allergies by Asthma and Allergy Foundation of America
WDRB
Louisville has been ranked the fourth worst city for allergies by the Asthma and Allergy Foundation of America. The foundation has released its 2016 list. Jackson, Mississippi tops the list, joined by Memphis, Tennessee and Syracuse, New York. An

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Protection against peanut allergy persists even after peanuts stopped

By Gene Emery (Reuters Health) – The technique of feeding peanuts to infants and young children who might be allergic not only protects them from a serious reaction immediately, but that protection persists even after the children stop eating peanut products, according to a new British study. The results were released at Friday’s annual meeting of American Academy of Allergy, Asthma and Immunology in Los Angeles one year after the researchers demonstrated for the first time that eating peanuts in infancy cut the risk of peanut allergies by 80 percent. “We wanted to make sure these children wouldn’t rebound and develop a peanut allergy” if the peanut therapy stopped.

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Alternaria alternata allergens: Markers of exposure, phylogeny and risk of fungi-induced respiratory allergy.

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Alternaria alternata allergens: Markers of exposure, phylogeny and risk of fungi-induced respiratory allergy.

Environ Int. 2016 Jan 27;89-90:71-80

Authors: Gabriel MF, Postigo I, Tomaz CT, Martínez J

Abstract
Alternaria alternata spores are considered a well-known biological contaminant and a very common potent aeroallergen source that is found in environmental samples. The most intense exposure to A. alternata allergens is likely to occur outdoors; however, Alternaria and other allergenic fungi can colonize in indoor environments and thereby increase the fungal aeroallergen exposure levels. A consequence of human exposure to fungal aeroallergens, sensitization to A. alternata, has been unequivocally associated with increased asthma severity. Among allergenic proteins described in this fungal specie, the major allergen, Alt a 1, has been reported as the main elicitor of airborne allergies in patients affected by a mold allergy and considered a marker of primary sensitization to A. alternata. Moreover, A. alternata sensitization seems to be a triggering factor in the development of poly-sensitization, most likely because of the capability of A. alternata to produce, in addition to Alt a 1, a broad and complex array of cross-reactive allergens that present homologs in several other allergenic sources. The study and understanding of A. alternata allergen information may be the key to explaining why sensitization to A. alternata is a risk factor for asthma and also why the severity of asthma is associated to this mold. Compared to other common environmental allergenic sources, such as pollens and dust mites, fungi are reported to be neglected and underestimated. The rise of the A. alternata allergy has enabled more research into the role of this fungal specie and its allergenic components in the induction of IgE-mediated respiratory diseases. Indeed, recent research on the identification and characterization of A. alternata allergens has allowed for the consideration of new perspectives in the categorization of allergenic molds, assessment of exposure and diagnosis of fungi-induced allergies.

PMID: 26826364 [PubMed – as supplied by publisher]

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Allergy to hedgehog with carboxypeptidase and chitinase-like and chymotrypsin-like elastase family members as the relevant allergens.

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Allergy to hedgehog with carboxypeptidase and chitinase-like and chymotrypsin-like elastase family members as the relevant allergens.

Ann Allergy Asthma Immunol. 2016 Jan 7;

Authors: González-de-Olano D, Muñoz-García E, Haroun-Díaz E, Bartolomé B, Pastor-Vargas C

PMID: 26774975 [PubMed – as supplied by publisher]

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