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Allergy and Asthma Sufferers Beware as Holiday Season Kicks In
U.S. News & World Report SATURDAY, Nov. 21, 2015 (HealthDay News) — There are a number of steps people with allergies and asthma can take to deal with the challenges they may face over the holidays, an expert says. "Two-thirds of allergy sufferers have symptoms year-round, … Weight gain in childhood could worsen asthma in later years |
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Allergy and Asthma Sufferers Beware as Holiday Season Kicks In
HealthDay SATURDAY, Nov. 21, 2015 (HealthDay News) — There are a number of steps people with allergies and asthma can take to deal with the challenges they may face over the holidays, an expert says. "Two-thirds of allergy sufferers have symptoms year-round, … |
View full post on asthma – Google News
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Allergy & Asthma Network Urges Support for Airline Access to Emergency …
PR Newswire (press release) "While these prevention strategies are appreciated," says Tonya Winders, President and CEO of Allergy & Asthma Network, "Congress is poised to do much more: Senate Bill 1972, the Airline Access to Emergency Epinephrine Act, will increase awareness … |
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Allergy & Asthma Network, ACAAI to Host 2015 Asthma Coalition Summit in San …
PR Newswire (press release) SAN ANTONIO, Oct. 29, 2015 /PRNewswire-USNewswire/ — Allergy & Asthma Network, the leading national nonprofit patient education and advocacy organization, is partnering with the American College of Allergy, Asthma and Immunology (ACAAI) to host … |
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ABC Online |
app to track allergy and asthma symptoms unveiled in Tasmania
ABC Online An app that allows people with allergy and asthma issues to track their symptoms and receive air quality alerts has been unveiled in Tasmania. AirRater brings together data from the Environment Protection Authority's air pollution monitors, BOM weather … |
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| Related Articles |
FoxP3 Tregs Response to Sublingual Allergen Specific Immunotherapy in Children Depends on the Manifestation of Allergy.
J Immunol Res. 2015;2015:731381
Authors: Stelmaszczyk-Emmel A, Zawadzka-Krajewska A, G?odkowska-Mrówka E, Demkow U
Abstract
Over the last decades allergic diseases has become a major health problem worldwide. The only specific treatment to date is allergen specific immunotherapy (ASIT). Although it was shown that ASIT generates allergen-tolerant T cells, detailed mechanism underlying its activity is still unclear and there is no reliable method to monitor its effectiveness. The aim of our study was to evaluate ASIT influence on the frequency of forkhead box P3 (FoxP3) Tregs in allergic children with various clinical manifestations. The relative number of FoxP3 Tregs in 32 blood samples from allergic children at baseline and/or after 1 year of ASIT was assessed by flow cytometry. In the entire studied group, the percentage of FoxP3 Tregs did not increase 1 year after ASIT. Nevertheless, the percentage of FoxP3 Tregs after ASIT significantly increased in children with respiratory allergy (conjunctivitis, asthma, and rhinitis) coexisting with nonrespiratory manifestations (food allergy and/or atopic dermatitis), whereas, in patients with respiratory allergy only, the percentage of FoxP3 Tregs decreased. To the best of our knowledge, this is the first report showing various differential FoxP3 Tregs response to ASIT in allergic children. FoxP3 Tregs number could be useful in treatment monitoring. Further studies are warranted to confirm these observations.
PMID: 26457309 [PubMed – in process]
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FOXP3 mRNA expression lower among children with asthma, food allergy
Healio Aneta Krogulska, MD, PhD, of the department of pediatric allergology, gastroenterology and nutrition at Medical University of Lodz in Poland, and colleagues assessed FOXP3 mRNA expression in 82 children with asthma. Fifteen had atopic asthma and an … |
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Dallas Morning News |
Allergy & Asthma Network Statement On EPA's New Ozone Standards
PR Newswire (press release) Allergy & Asthma Network is the leading national nonprofit organization dedicated to ending needless death and suffering due to asthma, allergies and related conditions. Allergy & Asthma Network specializes in sharing family-friendly, medically … EPA tightening limits on smog-causing ozone linked to asthma, respiratory illness |
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Allergy immunotherapy prevents asthma in patients with allergic rhinitis
Healio “Allergy immunotherapy effectively prevents the progression of allergic rhinitis to asthma in a real-life setting. This asthma-preventive effect is strongest in products containing native allergens,” Jochen Schmitt, MD, MPH, of the Center for Evidence … |
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Related Articles |
Genetics of allergy and allergic sensitization: common variants, rare mutations.
Curr Opin Immunol. 2015 Sep 16;36:115-126
Authors: Bønnelykke K, Sparks R, Waage J, Milner JD
Abstract
Our understanding of the specific genetic lesions in allergy has improved in recent years due to identification of common risk variants from genome-wide association studies (GWAS) and studies of rare, monogenic diseases. Large-scale GWAS have identified novel susceptibility loci and provided information about shared genetics between allergy, related phenotypes and autoimmunity. Studies of monogenic diseases have elucidated critical cellular pathways and protein functions responsible for allergy. These complementary approaches imply genetic mechanisms involved in Th2 immunity, T-cell differentiation, TGF? signaling, regulatory T-cell function and skin/mucosal function as well as yet unknown mechanisms associated with newly identified genes. Future studies, in combination with data on gene expression and epigenetics, are expected to increase our understanding of the pathogenesis of allergy.
PMID: 26386198 [PubMed – as supplied by publisher]
View full post on pubmed: asthma