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Low birth weight not associated with asthma risk
Medical Xpress "Asthma is the most common chronic illness in childhood and is a leading reason for missed school days," said allergist Hyeon Yang, M.D., lead study author. "While environment, genetics, and their interaction are thought to increase one's risk of … Asthma Not Linked to Birth Weight |
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 Medscape |
Asthma Associated With Pulmonary Embolism
Medscape Add asthma to the list of inflammatory disorders, such as rheumatoid arthritis and inflammatory bowel disease, that are associated with activated coagulation and an increased risk for venous thromboembolic events (VTEs), the authors of a new study say. Asthma Linked to Increased Risk of Dangerous Lung Blockage Severe asthma increases the risk of blood clots in lung Asthma increases blood clot risk |
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 Examiner.com |
IVF Associated With Increased Risk for Childhood Asthma
Medscape Children who were born after a prolonged time to conception are more likely to be diagnosed with asthma, experience wheezing in the last year, and be prescribed anti-asthmatic medication. This association is particularly true for children born after … Kids May Be at Slightly Higher Asthma Risk If Parents Had Infertility Treatments Risk of Asthma Up for Children Born After Fertility Treatment A new study suggests childhood asthma is caused by infertility treatments |
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Vitamin D Deficiency Associated with Poor Lung Function in Asthmatic Children
news Stories The deficiency was associated with poorer lung function in asthmatic children treated with inhaled corticosteroids. |
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 The Associated Press |
Indian believers swallow live fish as asthma cure
The Associated Press HYDERABAD, India (AP) — Tens of thousands of asthma-sufferers mobbed a southern Indian stadium Friday to swallow live sardines smeared with a yellow herbal paste they believe will cure their breathing problems. Despite doctors' criticism, the Goud … |
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 AFP |
US wants 9/11 health program to include 50 cancers
The Associated Press Previously, the aid effort has only covered people with mostly less-serious ailments, including asthma, acid reflux disease and chronic sinus irritation. The decision on whether to add cancer to that list is a difficult one, and there are still … US proposes expanding aid for sick 9/11 responders, NYC residents to include … |
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[Asthma and associated factors in students 13 and 14 years of age in São Luís, Maranhão State, Brazil].
Cad Saude Publica. 2012 Jun;28(6):1046-56
Authors: Lima WL, Lima EV, Costa Mdo R, Santos AM, Silva AA, Costa ES
Abstract
The aim of this study was to estimate the prevalence of asthma and associated factors among students 13 and 14 years of age in São Luís, Maranhão State, Brazil. A cross-sectional study was conducted using the questionnaire developed by ISAAC (International Study of Asthma and Allergies in Childhood) and an additional questionnaire from July 2008 to May 2009, including 3,069 adolescents. Asthma prevalence (wheezing in the previous 12 months) was 12.7%, lifetime prevalence was 32.4%, 3.9% reported difficulty speaking due to wheezing, and 9.8% reported wheezing after exercise. In the multivariate analysis, factors associated with increased asthma prevalence were family history of asthma, respiratory infection and wheezing in early life, eczema, allergic rhinitis, and passive smoking. Asthma prevalence was lower than for Brazil as a whole. Factors most strongly associated with asthma prevalence in these adolescents were family history of asthma (PR = 3.86), wheezing in early childhood (PR = 4.58), and allergic rhinitis (PR = 3.21).
PMID: 22666809 [PubMed – in process]
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America's Epidemics Associated with Poor Asthma Control
Newswise (press release) Newswise — ARLINGTON HEIGHTS, Ill. (June 1, 2012) – More bad news has surfaced for the 3.1 million baby boomers and older adults with asthma, a number that is expected to double within the next 25 years. According to a study published in the June … Summer's Heat May Enflame Hives |
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Asthma Prevention by Lactobacillus Rhamnosus in a Mouse Model is Associated With CD4(+)CD25(+)Foxp3(+) T Cells.
Allergy Asthma Immunol Res. 2012 May;4(3):150-6
Authors: Jang SO, Kim HJ, Kim YJ, Kang MJ, Kwon JW, Seo JH, Kim HY, Kim BJ, Yu J, Hong SJ
Abstract
PURPOSE: Probiotic bacteria can induce immune regulation or immune tolerance in allergic diseases. The underlying mechanisms have been recently investigated, but are still unclear. The aim of this study was to evaluate the protective effects of the probiotic Lactobacillus rhamnosus (Lcr35) in a mouse model of asthma and to identify its mechanism of action.
METHODS: Lcr35 was administered daily by the oral route at a dosage of 1×10(9) CFU/mouse in BALB/c mice for 7 days before the first sensitization. Clinical parameters and regulatory T (Treg) cells were examined. The role of CD4(+)CD25(+)Foxp3(+) Treg cells was analyzed using a Treg cell-depleting anti-CD25 monoclonal antibody (mAb).
RESULTS: Airway hyperresponsiveness, total IgE production, pulmonary eosinophilic inflammation, and splenic lymphocyte proliferation were suppressed after Lcr35 treatment. Th1 (IFN-?) and Th2 (IL-4, IL-5, and IL-13) cytokines in the serum were suppressed, and the percentage of CD4(+)CD25(+)Foxp3(+) Treg cells in the spleen was significantly increased in the Lcr35 treatment group. Anti-CD25 mAb administration abolished the protective effects of Lcr35, indicating that CD4(+) CD25(+)Foxp3(+) Treg cells are essential in mediating the activity of Lcr35.
CONCLUSIONS: Oral administration of Lcr35 attenuated the features of allergic asthma in a mouse model and induced immune regulation by a CD4(+)CD25(+)Foxp3(+) Treg cell-mediated mechanism.
PMID: 22548208 [PubMed – in process]
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GERD Associated With Worse Infant Respiratory Disease
Family Practice News Digital Network Bronchiolitis is a prominent risk factor for childhood asthma, and GERD is associated with worsened asthma severity (J. Asthma 2011;48:366-73). As yet unknown is whether preexisting GERD (clinically significant reflux) in infants modulates the severity … |
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