Tag: Associations

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Associations of Physical Activity and Sedentary Behavior with Atopic Disease in United States Children.

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Associations of Physical Activity and Sedentary Behavior with Atopic Disease in United States Children.

J Pediatr. 2016 May 4;

Authors: Strom MA, Silverberg JI

Abstract
OBJECTIVES: To determine if eczema, asthma, and hay fever are associated with vigorous physical activity, television/video game usage, and sports participation and if sleep disturbance modifies such associations.
STUDY DESIGN: Data were analyzed from 2 cross-sectional studies including 133?107 children age 6-17 years enrolled in the 2003-2004 and 2007-2008 National Survey of Children’s Health. Bivariate and multivariate survey logistic regression models were created to calculate the odds of atopic disease and atopic disease severity on vigorous physical activity, television/video game use, and sports participation.
RESULTS: In multivariate logistic regression models controlling for sociodemographic factors, lifetime history of asthma was associated with decreased odds of ?1 days of vigorous physical activity (aOR, 0.87; 95% CI, 0.77-0.99) and decreased odds of sports participation (0.91; 95% CI, 0.84-0.99). Atopic disease accompanied by sleep disturbance had significantly higher odds of screen time and lower odds of sports participation compared with children with either atopic disease or sleep disturbance alone. Severe eczema (aOR, 0.39; 95% CI, 0.19-0.78), asthma (aOR, 0.29; 95% CI, 0.14-0.61), and hay fever (aOR, 0.48; 95% CI, 0.24-0.97) were all associated with decreased odds of ?1 days of vigorous physical activity. Moderate (aOR, 0.76; 95% CI, 0.57-0.99) and severe eczema (aOR, 0.45; 95% CI, 0.28-0.73), severe asthma (aOR, 0.47; 95% CI, 0.25-0.89), and hay fever (aOR, 0.53; 95% CI, 0.36-0.61) were associated with decreased odds of sports participation in the past year.
CONCLUSIONS: Children with severe atopic disease, accompanied by sleep disturbance, have higher risk of sedentary behaviors.

PMID: 27156181 [PubMed – as supplied by publisher]

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Adult Orbital Xanthogranulomatous Disease: A Review with Emphasis on Etiology, Systemic Associations, Diagnostic Tools, and Treatment.

Adult Orbital Xanthogranulomatous Disease: A Review with Emphasis on Etiology, Systemic Associations, Diagnostic Tools, and Treatment.

Dermatol Clin. 2015 Jul;33(3):457-63

Authors: Kerstetter J, Wang J

Abstract
Adult orbital xanthogranulomatous diseases are rare entities and encompass a group of disorders with varying manifestations that are poorly understood. Taken as a group, there are non-Langerhans histiocytic disorders (type II) that are diagnosed histologically by the presence of foamy histiocytes, Touton giant cells, and varying degrees of fibrosis. Based on the accompanying systemic associations, there are 4 main categories of adult xanthogranulomatous disease: adult-onset xanthogranuloma, adult-onset asthma and periocular xanthogranuloma, necrobiotic xanthogranuloma, and Erdheim-Chester disease. Herein, we discuss the etiopathogenesis, systemic associations, methods of diagnosis, and treatment options for these disorders.

PMID: 26143425 [PubMed – in process]

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American Lung Association’s Champ Camp for Kids with Asthma offers full … – Niagara Frontier Publications

American Lung Association's Champ Camp for Kids with Asthma offers full …
Niagara Frontier Publications
The American Lung Association of the Northeast is now accepting applications for its Champ Camp for Kids with Asthma, which is being held this year at Camp Chingachgook, located on Lake George in Kattskill Bay (from Sunday, Aug. 17, through Friday …

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Human rhinovirus and wheezing: short and long-term associations in children.

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Human rhinovirus and wheezing: short and long-term associations in children.

Pediatr Infect Dis J. 2013 Aug;32(8):827-33

Authors: van der Gugten AC, van der Zalm MM, Uiterwaal CS, Wilbrink B, Rossen JW, van der Ent CK

Abstract
OBJECTIVES: Human rhinoviruses (HRVs) have been suggested to play a role in the development of childhood wheezing. However, whether HRV is causally related to the development of wheezing or HRV-associated wheeze is merely an indicator of disease susceptibility is unclear. Our aim was to study the role of HRV during infancy in the development of lower respiratory disease during infancy and childhood.
METHODS: In a population-based birth cohort, during the 1st year of life, nose and throat swabs were collected on a monthly basis, regardless of any symptoms. Polymerase chain reaction was used to detect an extensive panel of respiratory pathogens. Lung function was measured before 2 months of age. Information on respiratory symptoms was collected by daily questionnaires and electronic patient files.
RESULTS: 1425 samples were collected in 140 infants. Both the presence of (single or multiple) pathogens (HRV equal to other pathogens) and increased respiratory system resistance were significantly associated with lower respiratory symptoms during infancy. HRV presence during infancy was not associated with the risk of wheezing at age 4, but every HRV episode with wheezing increased the risk of wheezing at age 4 (odds ratio 1.9, 1.1-3.5). This association weakened after adjustment for lung function (odds ratio 1.4, 0.7-2.9).
CONCLUSIONS: HRV and other viruses are associated with lower respiratory symptoms during infancy, as well as a high presymptomatic respiratory system resistance. HRV presence during infancy is not associated with childhood wheezing, but wheeze during a HRV episode is an indicator of children at high risk for childhood wheeze, partly because of a reduced neonatal lung function.

PMID: 23584579 [PubMed – indexed for MEDLINE]

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23andMe helps identify 11 new genetic associations for asthma-with-hay fever – Science Codex

23andMe helps identify 11 new genetic associations for asthma-with-hay fever
Science Codex
Mountain View, Calif. –January 28, 2014 23andMe, the leading personal genetics company, has participated in the first ever genome-wide association study of the combined asthma-with-hay fever phenotype. Led by researchers at the QIMR Berghofer …

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Anika Noni Rose Celebrates the American Lung Association’s 2012 Christmas … – San Francisco Chronicle

Anika Noni Rose Celebrates the American Lung Association's 2012 Christmas …
San Francisco Chronicle
Actress, singer, and Tony Award winner Anika Noni Rose is serving as the American Lung Association's 2012 Christmas Seals® Celebrity Chairperson for a second consecutive year to share her story of her struggle with asthma and to support the …

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Anika Noni Rose Named American Lung Association’s 2012 Christmas Seals … – Broadway World

Anika Noni Rose Named American Lung Association's 2012 Christmas Seals …
Broadway World
Today, it is the nation's oldest direct-mail fundraising campaign and the money raised helps the Lung Association fight new battles against lung cancer, influenza, asthma, tobacco use, air pollution and more. Throughout its illustrious history, the …

and more »

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National Patient Advocacy and Medical Professional Associations: Freedom to Breathe

National Patient Advocacy and Medical Professional Associations: Freedom to Breathe Act Won’t Help Patients

By Allergy & Asthma Network Mothers of Asthmatics

Groups Say Congress Should Issue Vouchers to Assist with Transition from Epinephrine Inhalers, Monitor Patient Safety

New legislation from U.S. Senator Pat Roberts (R-KS) and an amendment by Senator Jim DeMint (R-SC) seek to allow epinephrine inhalers that contain chlorofluorocarbon (CFC) propellants to stay on the market, rather than being removed as agreed to in an international treaty ratified by all U.N.-recognized nations. Allergy & Asthma Network Mothers of Asthmatics (AANMA) and a group of patient advocacy and medical professional organizations wrote the senators today to explain that this exception would benefit only the drugs’ manufacturer, not patients with asthma.

“These well-intentioned measures not only don’t solve the problem, they totally negate the significant financial and personal sacrifices millions of us have already made with our transitioned prescription medications,” said AANMA President Nancy Sander. “If the senators really want to help families, they should issue vouchers through physicians. For example, patients who turn in their over-the-counter epinephrine inhalers to medical care providers could receive a free voucher for each new medication prescribed.”

On Dec. 31, 2011, after nearly 20 years’ warning, Primatene Mist®, which is inhaled epinephrine, and its generic copies made by Armstrong Pharmaceuticals will no longer be sold in the United States because they contain CFC propellants and do not meet criteria for an essential use exemption from U.S. and international treaties signed by Congress to eliminate ozone-depleting CFCs.

Primatene Mist was developed over 50 years ago and is no longer recommended for use by patients with asthma. The National Institutes of Health (NIH) developed National Guidelines for the Diagnosis and Management of Asthma two decades ago and has updated them three times since as a result of new evidence-based science concerning the disease of asthma. Neither NIH asthma guidelines nor the Global Initiative for Asthma (GINA) guidelines recommend epinephrine inhalers for the treatment of asthma.

Two inhalations of epinephrine provide breathing relief for approximately 15-30 minutes along with serious side effects, whereas two inhalations of prescription bronchodilators, recommended medication by NIH for asthma, last 3-6 hours with less unwanted cardiac stimulation. Primatene Mist is not a cheaper alternative — over the long term, it is more money for far less relief and worse side effects. Knowledge of the disease of asthma has drastically changed the way it is treated, and not surprisingly, 1950s treatments are no longer considered safe or up to current alternative treatment standards.

“Many patients who use OTC epinephrine exclusively often don’t know what they are missing until they experience how life could be with the right asthma action plan,” said Sander. “AANMA stands ready to help OTC epinephrine patients and families find better treatment options and outcomes as they make this transition.”

About AANMAAllergy & Asthma Network Mothers of Asthmatics (AANMA) is the leading national nonprofit organization dedicated to ending needless death and suffering due to asthma, allergies and related conditions. AANMA specializes in sharing family-friendly, medically accurate information through its award-winning publications Allergy & Asthma Today magazine and The MA Report newsletter, its website at www.aanma.org and numerous community outreach programs. Follow AANMA on Facebook at www.facebook.com/AANMA and Twitter at www.twitter.com/AANMA.

Contact:

Sandra Fusco-Walker

Director, Patient Advocacy

Allergy & Asthma Network

Mothers of Asthmatics

703-641-9595, ext. 1524

sfwalker@aanma.org

SOURCE Allergy & Asthma Network Mothers of Asthmatics

Read more: http://www.sacbee.com/2011/10/28/4014483/national-patient-advocacy-and.html#ixzz1c8elaJhK