Efficacy and Safety Study Comparing Respimat ® Budesonide With Turbohaler ® Budesonide in Symptomatic Adult Moderate to Severe Asthmatics Requiring Inhaled Corticosteroids and Bronchodilator Therapy

Condition:   Asthma
Interventions:   Drug: Respimat® Budesonide low dose;   Drug: Respimat® Budesonide high dose;   Drug: Turbohaler® Budesonide;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Completed – verified July 2014

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Junk food is so bad for asthmatics it can make inhalers ‘useless’, doctors warn – Daily Mail


Yahoo!7 News

Junk food is so bad for asthmatics it can make inhalers 'useless', doctors warn
Daily Mail
Eating fast food and consuming sugary drinks renders the most common asthma inhaler ineffective, a study warns. The findings are worrying because asthmatics tend to eat a diet high in saturated fat and sugar, the Australian researchers found. Therefore …
Poor diet link to worsened asthmaSydney Morning Herald
Asthma and diet: Researchers offer healthy foods chart for sufferersYahoo!7 News
Asthma Patients Should Strictly Avoid Junk Food: ResearchersNews on Wellness

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View full post on asthma – Google News

Sahara dust storm prompts ‘serious’ health warning for asthmatics – Telegraph.co.uk


Telegraph.co.uk

Sahara dust storm prompts 'serious' health warning for asthmatics
Telegraph.co.uk
The Saharan dust storm could trigger a spike in asthma attacks and also lead to previously undiagnosed sufferers developing the condition, a leading expert has warned. Dr Keith Prowse, Honorary Medical Adviser to the British Lung Foundation said

View full post on asthma – Google News

Association Analysis Between FILIP1 Polymorphisms and Aspirin Hypersensitivity in Korean Asthmatics.

Related Articles

Association Analysis Between FILIP1 Polymorphisms and Aspirin Hypersensitivity in Korean Asthmatics.

Allergy Asthma Immunol Res. 2013 Jan;5(1):34-41

Authors: Kim JY, Kim JH, Park BL, Pasaje CF, Bae JS, Park JS, Jang AS, Uh ST, Kim YH, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD

Abstract
PURPOSE: Aspirin exacerbated respiratory disease (AERD) results in a severe asthma attack after aspirin ingestion in asthmatics. The filamin A interacting protein 1 (FILIP1) may play a crucial role in AERD pathogenesis by mediating T cell activation and membrane rearrangement. We investigated the association of FILIP1 variations with AERD and the fall rate of forced expiratory volume in one second (FEV1).
METHODS: A total of 34 common FILIP1 single nucleotide polymorphisms (SNPs) were genotyped in 592 Korean asthmatic subjects that included 163 AERD patients and 429 aspirin-tolerant asthma (ATA) controls.
RESULTS: This study found that 5 SNPs (P=0.006-0.01) and 2 haplotypes (P=0.01-0.03) of FILIP1 showed nominal signals; however, corrections for the multiple testing revealed no significant associations with the development of AERD (P(corr)>0.05). In addition, association analysis of the genetic variants with the fall rate of FEV1, an important diagnostic marker of AERD, revealed no significant evidence (P(corr)>0.05).
CONCLUSIONS: Although further replications and functional evaluations are needed, our preliminary findings suggest that genetic variants of FILIP1 might be not associated with the onset of AERD.

PMID: 23277876 [PubMed – in process]

View full post on pubmed: asthma