Medical care and treatment of allergic rhinitis. A population-based cohort study based on routine healthcare utilization data.

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Medical care and treatment of allergic rhinitis. A population-based cohort study based on routine healthcare utilization data.

Allergy. 2016 Jan 8;

Authors: Schmitt J, Stadler E, Küster D, Wüstenberg EG

Abstract
BACKGROUND: Health services research on medical care and treatment of allergic rhinitis (AR) is scarce.
OBJECTIVES: To investigate the prevalence, incidence, comorbidities, and treatment of AR in a realistic setting.
METHODS: A cohort of 1,811,094 German National Health Insurance beneficiaries in 2005 was followed until 2011. To avoid misclassification, the ICD-10-code for AR (J30) had to be documented at least twice to classify patients as having AR. Descriptive statistics and logistic regression models were used to describe the burden, comorbidities, and treatment of AR.
RESULTS: A total of 111,394 patients (6.2%) had prevalent AR in 2005/2006. In another 60,145 individuals (3.3%) AR was newly diagnosed in 2007 to 2011 (incident cases). Patients with prevalent AR were three times more likely to develop asthma compared to patients without AR (age and sex-adjusted risk ratio (RR) 3.04; 95% confidence interval (95%CI) 2.98 – 3.10). Newly diagnosed recurrent depressive disorder (RR 1.61; 95%CI 1.55 – 1.68), anxiety disorder (RR 1.52; 95%CI 1.48 – 1.56) and ADHD (RR 1.21; 95%CI 1.13 – 1.29) were also related to prevalent AR. Approximately 20% of children and 36% of adults with AR were exclusively treated by general practitioners. Allergy immunotherapy (AIT) was prescribed for 16.4% of AR patients. Subcutaneous immunotherapy was most frequently used (80% of AIT).
CONCLUSIONS: This study highlights the significant burden of AR. Despite the established benefits of AIT to treat AR and prevent asthma this study suggests significant undertreatment. Future research is necessary to develop and implement adequate measures to increase guideline adherence. This article is protected by copyright. All rights reserved.

PMID: 26749452 [PubMed – as supplied by publisher]

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Caesarean Section and Hospitalization for Respiratory Syncytial Virus Infection: A Population Based Study.

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Caesarean Section and Hospitalization for Respiratory Syncytial Virus Infection: A Population Based Study.

Pediatr Infect Dis J. 2014 Sep 17;

Authors: Kristensen K, Fisker N, Haerskjold A, Ravn H, Simões EA, Stensballe L

Abstract
BACKGROUND AND OBJECTIVE:: Hospitalization for respiratory syncytial virus (RSV) infection and asthma share common determinants, and meta-analyses indicate that children delivered by caesarean section (CS) are at increased risk of asthma. We aimed to investigate whether birth by CS is associated with an increased risk of hospitalization for RSV illness.
METHODS:: This was a population based national register based cohort study, conducted between January 1997 and June 2003, that included all children born in Denmark and all hospitalizations for RSV disease in them from 0 – 23 months of age. We used Cox regression with adjustment for prematurity, asphyxia, birth weight, multiple births, single parenthood, maternal smoking during pregnancy, older siblings, and asthma diagnoses up to 2 weeks before hospitalization for RSV infection, to compare the effects of acute or elective CS versus vaginal delivery, on subsequent hospitalization for RSV disease. A test for homogeneity was used to assess for effect over time.
RESULTS:: 399,175 children with 10,758 hospitalizations for RSV illness were included. 31,715 were born by acute CS and 30,965 by elective CS. Adjusted hazard ratios for hospitalization for RSV infection in children born by acute CS and by elective CS were 1.09 (1.01 – 1.17) and 1.27 (1.19 – 1.36), respectively. The effect of elective CS remained unchanged throughout the first two years of life (p = 0.53), whereas the effect of acute CS was only present in the second year of life (p = 0.001).
CONCLUSION:: Delivery by caesarian section is associated with an increased risk of hospitalization for RSV infeciton. This effect continues at least throughout the first two years of life.

PMID: 25232778 [PubMed – as supplied by publisher]

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Prevalence of Asthma Symptoms based on the European Community Respiratory … – 7thSpace Interactive (press release)

Prevalence of Asthma Symptoms based on the European Community Respiratory
7thSpace Interactive (press release)
FENO is increased in patients with asthma. The relationship between subjective asthma symptoms and airway inflammation is an important issue. We expected that the subjective asthma symptoms in women might be different from those in men.

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UN helps Iran phase out asthma treatments based on ozone-depleting substances – UN News Centre


UN News Centre

UN helps Iran phase out asthma treatments based on ozone-depleting substances
UN News Centre
With support from the United Nations, Iran today became the first country in the Asia-Pacific region to phase out metered dose inhalers – used to treat asthma and other pulmonary ailments – and based on chlorofluorocarbons (CFCs), which contribute to
UN praises Iran's efforts to protect Ozone layerPress TV

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