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This biomarker can sort out asthma from allergies
Futurity: Research News People with asthma have telltale molecules circulating in their blood, report researchers. The discovery could lead to the first diagnostic blood test for asthma, as well as more targeted treatments for the condition. “Right now, we diagnose asthma … |
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VNN1 Gene Could Serve As a Biomarker for Response to Corticosteroids in …
Lung Disease News According to study investigator Gurjit Khurana Hershey, MD, PhD, director of Asthma Research at Cincinnati Children's Hospital Medical Center, “Genome-wide analysis allowed us to identify a gene, whose expression discriminated between good and poor … |
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VNN1 gene may be potential biomarker for childhood asthma
Clinical Advisor HealthDay News — A gene that affects whether children with asthma respond to corticosteroids has been identified, according to study findings published in the Journal of Allergy and Clinical Immunology. The gene "may serve as a clinically useful … |
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A pathophysiological approach for FeNO: A biomarker for asthma.
Allergol Immunopathol (Madr). 2015 Mar 18;
Authors: Ricciardolo FL, Sorbello V, Ciprandi G
Abstract
The present review is focused on literature concerning the relevance of fractional exhaled nitric oxide (FeNO) in clinical practice from a pathophysiological point of view. There is increasing evidence that asthma is a heterogeneous pathological condition characterised by different phenotypes/endotypes related to specific biomarkers, including FeNO, helpful to predict therapeutic response in selected asthmatic populations. Nowadays FeNO, a non-invasive biomarker, appears to be useful to foresee asthma developing, to recognise specific asthma phenotypes, like the eosinophilic, to ameliorate asthma diagnosis and management in selected populations and to predict standard corticosteroid and biologic therapy efficacy. In addition, FeNO assessment may also be useful in patients with allergic rhinitis in order to detect the potential involvement of eosinophilic bronchial inflammation in “case finding” subjects at risk of asthma diagnosis. Therefore, it is possible to hypothesise a future with an appropriate use of FeNO by physicians dealing with worrisome clinical issues in specific asthma phenotypes.
PMID: 25796309 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Asthma
Intervention: Procedure: Biofluid sampling
Sponsor: Boehringer Ingelheim
Not yet recruiting – verified March 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Genentech to Present at 2015 COPD & Asthma Conference on Biomarker …
Lung Disease News Biotechnology company Genentech has been invited to present at the 11th Asthma & COPD conference, an annual event that will gather some of the most internationally prominent scientists, clinicians and industry leaders to discuss the latest findings on … |
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Biomarker Panel Predicts Steroid Responsiveness in Asthma
Medscape A noninvasive panel of biomarkers can predict clinical responsiveness to inhaled corticosteroids (ICS) with a high degree of accuracy in patients with steroid-naive asthma, new research indicates. Douglas C. Cowan, MBChB, MRCP, PhD, from Dunedin … |
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Plasma connective tissue growth factor effective as asthma biomarker
Healio Plasma connective tissue growth factor levels were elevated in patients with stable asthma, according to recent study results. Researchers in Japan used the subtraction method to measure plasma connective tissue growth factor (CTGF) of 67 patients with … |
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Clusterin may be biomarker for asthma severity
Healio Clusterin may be a biomarker of asthma severity and the burden of oxidative stress in patients with asthma, and the expression may be a useful way to assess airway inflammation, according to data from a recent study. “Oxidative stress is important in … |
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Bench-to-Bedside Asthma Research to Study Potential Biomarker
Newswise (press release) Newswise — OMAHA, Neb. – What started as basic cancer research at Creighton University has yielded promising results for diagnosing and treating asthma – and the National Institutes of Health (NIH) agrees, investing nearly $1.5 million in Creighton to … |
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