Air toxins, asthma and lung cancer in East County: What’s the connection? – Antioch Herald

Air toxins, asthma and lung cancer in East County: What's the connection?
Antioch Herald
Air quality, optimal health and community growth are major concerns for residents of Contra Costa County. Equally important is the fact that business and industry are vital to economic development and sustainability. However, from time to time

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Basic cancer research at Creighton yields promising results for diagnosing … – News-Medical.net

Basic cancer research at Creighton yields promising results for diagnosing
News-Medical.net
What started as basic cancer research at Creighton University has yielded promising results for diagnosing and treating asthma – and the National Institutes of Health (NIH) agrees, investing nearly $1.5 million in Creighton to find out more. In a

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The Bakersfield walk for air supports those suffering from asthma, lung cancer … – KERO-TV 23


KERO-TV 23

The Bakersfield walk for air supports those suffering from asthma, lung cancer
KERO-TV 23
BAKERSFIELD, Calif. – The American Lung Association in California's fight for air walk was held today Saturday April 13 at Yuktus park. The walk was held to raise funds in support of the fight for healthy lungs and clean air. The walk supports those
MAKING APARTMENTS AND CONDOS SMOKE-FREEU-T San Diego

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Hay Fever and Asthma as Markers of Atopic Immune Response and Risk of Colorectal Cancer in Three Large Cohort Studies.

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Hay Fever and Asthma as Markers of Atopic Immune Response and Risk of Colorectal Cancer in Three Large Cohort Studies.

Cancer Epidemiol Biomarkers Prev. 2013 Mar 19;

Authors: Jacobs EJ, Gapstur SM, Newton CC, Turner MC, Campbell PT

Abstract
BACKGROUND: In a previous analysis of 12 cancers in the Cancer Prevention Study II (CPS-II) cohort including follow-up from 1982-2000, having both hay fever and asthma was associated with lower colorectal cancer mortality. The combination of these allergic conditions may be a marker for allergy-related immune responses that could inhibit colorectal carcinogenesis.METHODS: We examined the association of having both hay fever and asthma with colorectal cancer mortality among 1,023,191 participants in CPS-I, followed from 1959-1972, and 1,102,092 participants in CPS-II, now followed from 1982-2008. We also examined associations with colorectal cancer incidence among 174,917 participants in the CPS-II Nutrition Cohort, a subgroup of CPS-II followed from 1992-2007. During the follow-up, there were 5,644 colorectal cancer deaths in CPS-I, 13,558 colorectal cancer deaths in CPS-II, and 3,365 incident colorectal cancer cases in the CPS-II Nutrition Cohort. Cox proportional hazards regression was used to calculate multivariable-adjusted relative risks (RR) and 95% confidence intervals (CI).RESULTS: RRs for colorectal cancer mortality associated with having both asthma and hay fever, compared with neither condition, were 0.90 (95% CI, 0.74-1.09) in CPS-I, 0.79 (95% CI, 0.69-0.91) in CPS-II, and 0.83 (95% CI, 0.74-0.92) when results from both cohorts were combined in a meta-analysis. The corresponding RR for colorectal cancer incidence in the CPS-II Nutrition Cohort was 0.90 (95% CI, 0.71-1.14).CONCLUSION: These results support an association between having both hay fever and asthma and modestly lower colorectal cancer mortality.Impact: Research examining other potential markers of allergy-related immune response in relation to colorectal cancer is warranted. Cancer Epidemiol Biomarkers Prev; 22(4); 1-9. ©2013 AACR.

PMID: 23513040 [PubMed – as supplied by publisher]

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