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Do Asthmatic Children Grow Into Adults With COPD?
Medscape From a survey of 30,000 children aged 7 years, a group of 479 children with asthma (as defined by a questionnaire) and a control group similar to the asthmatic children were enrolled. The groups were followed with clinical evaluations, questionnaires … |
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Food allergies were not associated with asthma severity in children
Healio VANCOUVER, British Columbia — Food allergies were not associated with asthma severity among children and adolescents with asthma, according to data recently presented at the Pediatric Academic Societies Annual Meeting. Sandeep Puranik, MBBS … |
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Human rhinovirus and wheezing: short and long-term associations in children.
Pediatr Infect Dis J. 2013 Aug;32(8):827-33
Authors: van der Gugten AC, van der Zalm MM, Uiterwaal CS, Wilbrink B, Rossen JW, van der Ent CK
Abstract
OBJECTIVES: Human rhinoviruses (HRVs) have been suggested to play a role in the development of childhood wheezing. However, whether HRV is causally related to the development of wheezing or HRV-associated wheeze is merely an indicator of disease susceptibility is unclear. Our aim was to study the role of HRV during infancy in the development of lower respiratory disease during infancy and childhood.
METHODS: In a population-based birth cohort, during the 1st year of life, nose and throat swabs were collected on a monthly basis, regardless of any symptoms. Polymerase chain reaction was used to detect an extensive panel of respiratory pathogens. Lung function was measured before 2 months of age. Information on respiratory symptoms was collected by daily questionnaires and electronic patient files.
RESULTS: 1425 samples were collected in 140 infants. Both the presence of (single or multiple) pathogens (HRV equal to other pathogens) and increased respiratory system resistance were significantly associated with lower respiratory symptoms during infancy. HRV presence during infancy was not associated with the risk of wheezing at age 4, but every HRV episode with wheezing increased the risk of wheezing at age 4 (odds ratio 1.9, 1.1-3.5). This association weakened after adjustment for lung function (odds ratio 1.4, 0.7-2.9).
CONCLUSIONS: HRV and other viruses are associated with lower respiratory symptoms during infancy, as well as a high presymptomatic respiratory system resistance. HRV presence during infancy is not associated with childhood wheezing, but wheeze during a HRV episode is an indicator of children at high risk for childhood wheeze, partly because of a reduced neonatal lung function.
PMID: 23584579 [PubMed – indexed for MEDLINE]
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Asthma symptom perceptions varied among inner-city parents, children
Healio VANCOUVER, British Columbia — Clinicians should consider child reports of exercise-induced asthma symptoms and medication for asthma attacks to better identify those in need of improved disease management, according to data recently presented at the … |
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House dust mite SLIT effective for children with rhinitis, asthma
Healio House dust mite sublingual immunotherapy tablets were an effective treatment for children and adolescents with rhinitis and/or asthma due to house dust mite allergens, according to a recent study. “Symptoms of rhinitis and asthma were improved in … |
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Mobile clinics provide only asthma treatment for some Detroit children
The Detroit News Between 18-20 percent of Detroit Public School children have asthma, according to Ora Beard, principal of Dixon Educational Learning Academy in Detroit. Often left untreated because families don't have access to health care and schools don't have … |
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Hits & Myths: Is it OK to allow asthmatic children to play sport?
South China Morning Post Is it okay for kids with asthma to play sports? The straight answer: Yes. The facts: It's perfectly fine for asthmatic children to take up sports. In fact, many elite and Olympic athletes are asthmatic, like British marathon runner Paula Radcliffe and … |
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Asthma in children needs persistent care
Toledo Blade “Asthma is a chronic disease and should be treated as such,” says Pierre Vauthy, M.D., a ProMedica Physicians pediatric pulmonologist who has cared for children with asthma and other lung conditions for more than 30 years. “Compared to when I started … |
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Getting treatment for asthma is difficult for children living in poverty
Michigan Radio “Children in poverty are at risk because they don't have the resources to rid their homes of things like mold and moisture, so it does take a lot of other referrals to help our families to decrease the asthma symptoms in the home,” said Jackson. That's … |
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Influenza vaccination in children at high risk of respiratory disease.
Ther Adv Vaccines. 2013 May;1(1):21-31
Authors: Patria MF, Tagliabue C, Longhi B, Esposito S
Abstract
Chronic respiratory diseases (CRDs) are a heterogeneous group of diseases that can affect the pediatric population and health authorities throughout the world recommend influenza vaccination because of the significant risk of influenza-related complications. However, despite this recommendation, vaccine coverage is generally unsatisfactory. The aim of this review is to analyze the impact of influenza on children at high risk of respiratory disease, and the immunogenicity, safety and efficacy of influenza vaccination in such children. The results show that there is a significant risk of influenza-related complications in preterm neonates and infants, in whom influenza vaccines are immunogenic and safe (although their efficacy has not been specifically studied). There are conflicting data concerning the effect of influenza infection on asthma morbidity in children, and whether or not influenza vaccination helps to prevent asthma exacerbations. Recent data provide no evidence that influenza is more frequent in patients with cystic fibrosis than in healthy subjects, or that it is responsible for increased lower respiratory tract morbidity. The lack of any clear correlate of protection suggests that future studies should also consider the efficacy of the different influenza vaccines and not only evaluate them in terms of immunogenicity. Furthermore, there is a need for clinical studies to assess the effectiveness of the available vaccines in patients with other rare CRDs and other chronic underlying diseases with possibly severe respiratory involvement. It is also important to determine whether children with recurrent respiratory tract infections should be included in the list of those for whom influenza vaccination is recommended. In the meantime, given the increasing evidence of the burden of influenza on the population as a whole and the benefits associated with vaccination, annual influenza vaccinations should be recommended for all children at high risk of respiratory disease and the members of their households.
PMID: 24757513 [PubMed]
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