Breathe Well Live Well
Condition: Moderate Asthma
Intervention: Device: Bronchial Thermoplasty
Sponsor: Guangzhou Institute of Respiratory Disease
Recruiting – verified November 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Asthma Treatment Drugs Market In China Growth & Trends: Radiant Insights, Inc
Medgadget.com (blog) This study focuses on China's Asthma Treatment Drugs industry assessments and company profiles. In the two past decades, the industry has been growing at a fast pace. The dramatic expansions of the manufacturing capabilities and rising consumer … |
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Condition: Asthma
Intervention: Behavioral: asthma APP
Sponsor: Shanghai Children’s Medical Center
Not yet recruiting – verified January 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
| Related Articles |
Genetic polymorphisms of the TNF-?-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China.
Int J Clin Exp Pathol. 2015;8(10):13739-46
Authors: Yang YH, Liu YQ, Zhang L, Li H, Li XB, Ouyang Q, Zhu GY
Abstract
Asthma is a complex inflammatory disease involving the critical actions of several important cytokines. Epidemiological data show that obesity could increase the risk of asthma, and insulin resistance, or metabolic syndrome are an important risk factor for obesity asthma. Some studies identified that upstream of the transcription start site within the TNF-? gene promoter region-308 polymorphism was associated insulin resistance or metabolic disorders, while this site was closely related to asthma. But no research was performed to evaluate the influence of TNF-?-308G/A polymorphism on metabolic syndrome in asthmatic patients. Here, we recruited 248 asthmatic patients, who were separated into asthma with Mets/asthma without Mets groups and 226 matched healthy controls from Hebei Province to evaluate the influence of TNF-?-308G/A polymorphism on metabolic syndrome in asthmatic patients. Single nucleotide polymorphism of TNF-?-308 locus was genotyped using PCR-RFLP. Some biochemical variables were also determined. Our result showed that the genotypic and allelic frequency of rs1800629 did not show significant difference between asthmatic patients and normal controls. However, the frequency of A allele was signi?cantly higher in asthma group with Mets (22.36%) than in controls (15.71%) (P = 0.02; OR = 0.647; 95% CI = 0.447-0.936). After analyzing the relationship between biochemical features of patients and genotype of TNF-?-308G/A, we found levels of LDL cholesterol, TNF-? and insulin, and HOMA-IR were significantly higher in the asthmatic patients carrying the GA and AA genotypes than in the carriers of GG genotype of rs1800629 (P = 0.029, P = 0.022, P = 0.043, respectively). Thus, our data suggested that TNF-?-308G/A variation was related to metabolic phenotype in asthma patients. Furthermore, we first identified TNF-?-308 A allele was the risk factor for asthmatic patients with Mets in Hebei population, China.
PMID: 26722602 [PubMed – in process]
View full post on pubmed: asthma
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Global and China Asthma Therapeutics Industry 2013 Market Analysis, Growth …
Medgadget.com (blog) Mrrbiz-Logo2119 “The Report Global and China Asthma Therapeutics Industry 2013 Market Research Report provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. – MarketResearchReports.biz”. |
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China Asthma Therapeutics Industry 2015 Market Research Report by ReportBazzar
Medgadget.com (blog) The China Asthma Therapeutics Industry 2015 Market Research Report is a professional and in-depth study on the current state of the Asthma Therapeutics industry. The report provides a basic overview of the industry including definitions … |
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China Asthma Therapeutics And Pharmacology Market Research Report, Shares …
Medgadget.com (blog) MrrBiz213 “China Asthma Therapeutics Industry 2015 Market Research Report” studies the current scenario as well as future market potential of “Pharmaceutical” globally. The China Asthma Therapeutics Industry 2015 Market Research Report is a … |
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Related Articles |
Early life exposure to ambient air pollution and childhood asthma in China.
Environ Res. 2015 Oct 7;143(Pt A):83-92
Authors: Deng Q, Lu C, Norbäck D, Bornehag CG, Zhang Y, Liu W, Yuan H, Sundell J
Abstract
BACKGROUND: Early life is suggested to be a critical time in determining subsequent asthma development, but the extent to which the effect of early-life exposure to ambient air pollution on childhood asthma is unclear.
OBJECTIVES: We investigated doctor-diagnosed asthma in preschool children due to exposure to ambient air pollution in utero and during the first year of life.
METHODS: In total 2490 children aged 3-6 years participated in a questionnaire study regarding doctor-diagnosed asthma between September 2011 and January 2012 in China. Children’s exposure to critical air pollutants, sulfur dioxide (SO2) as proxy of industrial air pollution, nitrogen dioxide (NO2) as proxy of traffic pollution, and particulate matter?10µm in diameter (PM10) as a mixture, was estimated from the concentrations measured at the ambient air quality monitoring stations by using an inverse distance weighted (IDW) method. Logistic regression analysis was employed to determine the relationship between early-life exposure and childhood asthma in terms of odds ratio (OR) and 95% confidence interval (CI).
RESULTS: Association between early-life exposure to air pollutants and childhood asthma was observed. SO2 and NO2 had significant associations with adjusted OR (95% CI) of 1.45 (1.02-2.07) and 1.74 (1.15-2.62) in utero and 1.62 (1.01-2.60) and 1.90 (1.20-3.00) during the first year for per 50µg/m(3) and 15µg/m(3) increase respectively. Exposure to the combined high level of SO2 and NO2 in China significantly elevated the asthmatic risk with adjusted OR (95% CI) of 1.76 (1.18-2.64) in utero and 1.85 (1.22-2.79) during the first year compared to the low level exposure. The associations were higher for males and the younger children aged 3-4 than females and the older children aged 5-6.
CONCLUSIONS: Early-life exposure to ambient air pollution is associated with childhood asthma during which the level and source of air pollution play important roles. The high level and nature of combined industrial and traffic air pollution in China may contribute to the recent rapid increase of childhood asthma.
PMID: 26453943 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
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China Asthma Therapeutics Industry 2015 Market Research Report
Medgadget.com (blog) The China Asthma Therapeutics Industry 2015 Market Research Report is a professional and in-depth study on the current state of the Asthma Therapeutics industry. The report provides a basic overview of the industry including definitions … |
View full post on asthma – Google News
South China Morning Post (subscription) |
If grandma smoked while pregnant with mum, your asthma risk is higher
South China Morning Post (subscription) Children with grandmothers who smoked have an increased risk of asthma even when mothers did not smoke, according to a new study presented at the European Respiratory Society's International Congress. Data was taken from the Swedish Registry and … Grandparent's Smoking Habits May Increase Asthma Risk In Grandchildren Grandmother's Smoking May Increase Asthma Risk in Grandchildren |
View full post on asthma – Google News