Breathe Well Live Well
Condition: Widespread Chronic Pain
Interventions: Drug: Ketotifen Fumarate; Drug: Placebo; Other: Standard of Care
Sponsors: McGill University Health Center; The Louise And Alan Edwards Foundation
Recruiting – verified December 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Related Articles |
Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma.
Inflammation. 2016 Nov 19;
Authors: Chauhan PS, Dash D, Singh R
Abstract
Pulmonary fibrosis is associated with irreversible, or partially reversible, airflow obstruction and ultimately unresponsiveness to asthma therapies such as corticosteroids. Intranasal curcumin, an anti-inflammatory molecule, has been found effective in allergic asthma. To study the effect of intranasal curcumin on airway remodeling and fibrosis in murine model of chronic asthma, BALB/c mice were sensitized to ovalbumin (OVA) and exposed to OVA aerosol (2%) from day 21 (after sensitization) for 5 weeks (twice/week). Curcumin (intranasal) was administered during the OVA aerosol challenge. Mice exposed to OVA developed inflammation dominated by eosinophils which lead to fibrosis and airway remodeling. Intranasal administration of curcumin significantly inhibited airway inflammation and pulmonary fibrosis, where MMP-9 activities were decreased along with ?-smooth muscle actin (?-SMA), MMP-9, TIMP-1, and eotaxin expressions. These results suggest that intranasal curcumin regulates airway inflammation and remodeling in chronic asthma.
PMID: 27866296 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: COPD
Intervention: Other: No intervention
Sponsor: Chinese University of Hong Kong
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Using Technology to Affect Influenza Vaccine Coverage Among Children With Chronic Respiratory Conditions.
J Pediatr Health Care. 2016 Jul 27;
Authors: Bay SL, Crawford DJ
Abstract
INTRODUCTION: Influenza presents additional burdens for children with chronic respiratory conditions. Influenza vaccinations may reduce complications, yet approximately half of children remain unprotected. Evidence supports integration of text and e-mail into multicomponent strategies to increase influenza vaccination rates among children with chronic respiratory conditions.
METHODS: A single text and e-mail message was sent to those with enabled preferences in the patient portal. A follow-up survey assessed aspects of message receipt. Surveys were completed without collection of demographics.
RESULTS: A total of 3,206 messages were successfully delivered. Surveys were initiated by 107 recipients. Frequency analysis showed that text and e-mail messages were preferred forms of communication. A statistically significant relationship was found between receiving a message and receiving an influenza vaccination (p = .027).
DISCUSSION: Text and e-mail messaging are cost effective and well received, and they can be easily integrated into existing systems. These methods are translatable across populations and can convey various types of messages.
PMID: 27475928 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Conditions: Asthma; Chronic Obstructive Pulmonary Disease
Interventions: Behavioral: Outreach education training; Behavioral: No outreach education training
Sponsors: University of Sao Paulo General Hospital; University of Sao Paulo; Santa Catarina Federal University; University of Cape Town; Federal University of Bahia; Medical Research Council, South Africa; University of East Anglia
Not yet recruiting – verified May 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Fluticasone furoate 100 mcg + Umeclidinium 62.5 mcg+Vilanterol 25 mcg; Drug: Fluticasone furoate 100 mcg + Vilanterol 25 mcg; Drug: Umeclidinium 62.5 mcg; Device: Placebo ELLIPTA inahler; Drug: Albuterol/Salbutamol
Sponsor: GlaxoSmithKline
Not yet recruiting – verified April 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Lung Disease News |
Potential Target for Severe Asthma, Other Chronic Inflammatory Diseases Identified
Lung Disease News From previous research it was known that Dkk-1, a protein produced by platelets (blood cells responsible for clotting), inhibits tissue repair, a feature that is common in chronic inflammatory disorders such as asthma, autoimmune diseases and cancer … |
View full post on asthma – Google News
Medical Xpress |
Study identifies new target for severe asthma, chronic inflammatory diseases
Medical Xpress Chronic inflammation is commonly found in asthma, autoimmune diseases, cancer, and viral infections, and it's characterized by constant activation of platelets with unhealed tissue damage. Scientists who have studied the Dkk-1 protein were aware that … |
View full post on asthma – Google News
Condition: Chronic Rhinosinusitis With Nasal Polyps
Interventions: Drug: Vitamin D; Drug: Budesonide Nasal Spray; Other: placebo
Sponsor: The First Affiliated Hospital of Shanxi Medical University
Not yet recruiting – verified January 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
| Related Articles |
Weakness in an Elderly Woman With Asthma and Chronic Sinusitis.
Neurohospitalist. 2016 Jan;6(1):36-40
Authors: Kannan M, Greene JG
Abstract
Weakness and sensory changes are common complaints in both the inpatient and the outpatient setting. However, this presentation remains a diagnostic challenge to clinicians due to the many possible underlying etiologies. The initial evaluation of weakness and sensory changes starts a thorough history and physical examination to guide the diagnostic process. In this article, we present the case of an elderly woman with complaints of weakness and sensory changes to highlight a step-wise approach to diagnosis and management.
PMID: 26753055 [PubMed]
View full post on pubmed: asthma