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Asthma Is the Most Common Chronic Disease Among Olympic Athletes
Science Daily (press release) In summer and winter sports there is widespread suffering from asthma and airway hyper-responsiveness (AHR) among athletes who take part in endurance sports. Its relatively late onset in many older athletes suggests to the experts that the years of … 8 Percent of Olympians Have Asthma |
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Asthma is the most common chronic disease among Olympic athletes
Science Codex In summer and winter sports there is widespread suffering from asthma and airway hyper-responsiveness (AHR) among athletes who take part in endurance sports. Its relatively late onset in many older athletes suggests to the experts that the years of … |
View full post on asthma – Google News
|
Asthma is the most common chronic disease among Olympic athletes
EurekAlert (press release) In summer and winter sports there is widespread suffering from asthma and airway hyper-responsiveness (AHR) among athletes who take part in endurance sports. Its relatively late onset in many older athletes suggests to the experts that the years of … |
View full post on asthma – Google News
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Asthma most common chronic disease among Olympians
Irish Health Researchers at the University of Western Australia looked at data from the last five Olympic games and identified athletes with asthma and airway hyper-responsiveness (AHR). They discovered that asthma and AHR had a prevalence of around 8% among the … |
View full post on asthma – Google News
Comparison of disease-specific quality-of-life instruments in the assessment of chronic rhinosinusitis.
Int Forum Allergy Rhinol. 2012 Jun 13;
Authors: Quintanilla-Dieck L, Litvack JR, Mace JC, Smith TL
Abstract
BACKGROUND: Many disease-specific, quality-of-life (QOL) instruments exist for chronic rhinosinusitis (CRS), resulting in confusion about the best application and use of each instrument. We hypothesized that the most prevalently utilized instruments do not strongly correlate in all domains, but rather act in complementary fashion for QOL assessment. METHODS: A systematic literature review (MEDLINE) was performed to identify the type and frequency of available CRS-specific QOL instruments. Univariate analyses of the 3 most common instruments (Rhinosinusitis Disability Index [RSDI], Chronic Sinusitis Survey [CSS] and 22-item Sinonasal Outcomes Test [SNOT-22]) were performed using a multi-institutional prospective cohort of sinusitis patients. RESULTS: Systematic literature review found that the SNOT-20 (and its derivatives), RSDI, and CSS are the most commonly utilized CRS-specific QOL instruments. The majority of RSDI domains were weakly or not correlated with the CSS domains (r = 0.097-0.501; p < 0.001). In contrast, the RSDI was highly correlated with the SNOT-22 (r ? 0.666; p < 0.001). Patients with asthma and/or allergies reported significantly worse CSS scores (p < 0.001). Comorbidities had no significant impact on RSDI or SNOT-22 responses. CONCLUSION: Different disease-specific CRS QOL instruments measure different aspects of the patient’s experience. The RSDI and SNOT-22 are more sensitive to measuring the emotional impact of CRS, whereas the CSS examines medication use and symptoms. These instruments play complementary roles in the evaluation of CRS treatment outcomes.
PMID: 22696495 [PubMed – as supplied by publisher]
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Chronic Disease? There's An App For That: 11 Hot Techs To Watch
WBUR Fifty percent of Americans have some sort of chronic disease, from high blood pressure to diabetes to asthma, and their care accounts for some 75 percent of the … |
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11 New Technologies To Manage Chronic Illness And Save Money
WBUR … asthmatic that he's driving through a known asthma-attack-inducing region and automatically switches the HVAC system to recirculate and close the windows, … The top new techs for tackling chronic diseases: report |
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Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism.
Mediators Inflamm. 2012;2012:438912
Authors: Uzkeser H, Cadirci E, Halici Z, Odabasoglu F, Polat B, Yuksel TN, Ozaltin S, Atalay F
Abstract
The possible role of ?-2 adrenergic receptors in modulation of inflammatory and nociceptive conditions suggests that the ?-2 adrenergic receptor agonist, salbutamol, may have beneficial anti-inflammatory and analgesic effects. Therefore, in this study, we induced inflammatory and nociceptive responses with carrageenan-induced paw edema or cotton-pellet-induced granuloma models, both of which result in oxidative stress. We hypothesized that salbutamol would prevent inflammatory and nociceptive responses by stimulating ?-2 adrenergic receptors and the prevention of generation of ROS during the acute inflammation process in rats. Both doses of salbutamol used in the study (1 and 2?mg/kg) effectively blocked the acute inflammation and inflammatory nociception induced by carrageenan. In the cotton-pellet-induced granuloma test, both doses of salbutamol also significantly decreased the weight of granuloma tissue on the cotton pellets when compared to the control. Anti-inflammatory and analgesic effects of salbutamol were found to be comparable with those of indomethacin. Salbutamol decreased myeloperoxidase (MPO) activity and lipid peroxidation (LPO) level and increased the activity of superoxide dismutase (SOD) and level of glutathione (GSH) during the acute phase of inflammation. In conclusion, salbutamol can decrease acute and chronic inflammation, possibly through the stimulation of ?-2 adrenergic receptors. This anti-inflammatory effect may be of significance in asthma treatment, where inflammation also takes part in the etiopathology. This study reveals that salbutamol has significant antioxidative effects, which at least partially explain its anti-inflammatory capabilities. These findings presented here may also shed light on the roles of ?-2 adrenergic receptors in inflammatory and hyperalgesic conditions.
PMID: 22665951 [PubMed – in process]
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Chronic asthma sufferers may have new hope for relief due to two BWH research …
News-Medical.net Chronic asthma sufferers may have new hope for relief due to two new research studies that are getting underway at Brigham and Women's Hospital (BWH). Researchers from BWH's Asthma Research Center are exploring whether two new therapies will relieve … |
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The New Art of Chronic Care
Wall Street Journal By LAURA LANDRO For decades, numbers drove the treatment of diseases like asthma, heart disease, diabetes, and arthritis. Public-health officials focused on reducing mortality rates and hitting targets like blood-sugar levels for people with diabetes … |
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