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IMPACT OF TRIALS ON CLINICAL PRACTICE: INTERVENTIONS IN SEPTIC SHOCK PATIENTS BETWEEN 2005 AND 2013.
Intensive Care Med Exp. 2015 Dec;3(Suppl 1):A430
Authors: Jones A, Bond A, Whiteley C, Cendreda B, Shankar-Hari M
PMID: 27289981 [PubMed]
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Clinical usefulness of mepolizumab in severe eosinophilic asthma
Dove Medical Press Abstract: Asthma is a chronic inflammatory disorder of the airways with variable clinical severity from very mild and occasional symptoms to recurrent critical exacerbations, at risk of fatal or near-fatal outcome, in a small percentage of patients … |
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Childhood asthma linked to young adult COPD risk
Clinical Advisor HealthDay News — Children with persistent asthma and reduced growth of lung function may be at increased risk for chronic obstructive pulmonary disease (COPD) in early adulthood, according to a study published in the May 12 issue of the New England … Allergy Partners Announces Topic of the Month: COPD vs. Asthma |
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Arizona Daily Star |
UA researcher receives $27 million for asthma clinical study
Arizona Daily Star A University of Arizona researcher will head a $27 million national clinical study that could lead to developing a prevention method for asthma in young children. The National Heart, Lung and Blood Institute, which is a part of the National Institutes … Preventive asthma drug for children getting closer, researchers say |
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Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.
J Gastroenterol. 2016 Apr 23;
Authors: Jiao D, Ishimura N, Maruyama R, Ishikawa N, Nagase M, Oshima N, Aimi M, Okimoto E, Mikami H, Izumi D, Okada M, Ishihara S, Kinoshita Y
Abstract
BACKGROUND: Esophageal eosinophilia is classified as either eosinophilic esophagitis (EoE) or proton-pump inhibitor-responsive esophageal eosinophilia (PPI-REE), depending on the response to PPI treatment. The aim of this study was to compare the clinical, endoscopic, and histopathological findings of EoE and PPI-REE in Japanese patients. In addition, the characteristics of these cases were compared with those of reflux esophagitis (RE) cases.
METHODS: Eleven patients diagnosed with EoE, 16 with PPI-REE, and 39 with RE, who were all consecutively examined from 2005 to 2015 at Shimane University Hospital, were enrolled. Clinical, endoscopic, and histopathological esophageal findings in these groups were retrospectively examined and compared.
RESULTS: The differences in the clinical characteristics of EoE and PPI-REE were not remarkable, though patients with EoE and PPI-REE were younger, presented a higher prevalence of allergic comorbidities, and complained of symptoms of dysphagia more frequently than those with RE. The only noteworthy differences between EoE and PPI-REE were more frequent reports of asthma (36.4 vs. 2.6 %) and food allergy (27.3 vs. 0 %) by patients with EoE (P < 0.05, P < 0.05, respectively). Endoscopic findings in patients with EoE and PPI-REE were similar, with the presence of esophageal erosions in a small percentage of PPI-REE cases being the only difference. There were no histopathological differences between EoE and PPI-REE.
CONCLUSIONS: Comparisons of clinical, endoscopic, and histopathological findings between EoE and PPI-REE showed that these two types have similar characteristics, though EoE patients showed a higher atopic background. Predicting PPI responsiveness in cases with esophageal eosinophilia is difficult and requires further investigation.
PMID: 27108416 [PubMed – as supplied by publisher]
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Clinical factors affecting quality of life of patients with asthma
Dove Medical Press Background: In recent years, there has been increased interest in the subjective quality of life (QoL) of patients with bronchial asthma. QoL is a significant indicator guiding the efforts of professionals caring for patients, especially chronically … |
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Asthma Therapeutics Clinical Trials Review H1 2016 Global Market Research Report
Medgadget.com (blog) WiseGuy-Reports112 WiseGuyReports.com adds“Asthma Therapeutics Clinical Trials Review H1 2016 Global Market Research Report”reports to its database. We can offer you discount on this report. GlobalData's clinical trial report, “Asthma Global Clinical … |
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Pediatric asthma is regularly overdiagnosed
Clinical Advisor Clinicians regularly overdiagnose asthma in children, leading to an increase in harmful side effects, according to an article published in the Archives of Disease in Childhood. Professor Andrew Bush, of the Department of Pediatric Respiratory Medicine … |
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The asthma–COPD overlap syndrome: how is it defined and what are its clinical implications?
Dove Medical Press Abstract: It is increasingly recognized that both asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases with a large inter-individual variability with respect to their clinical expression, disease progression, and … |
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ICD-10 codes may improve asthma care
Clinical Advisor According to preliminary feedback from primary care providers, the new ICD-10 coding system is frustrating and taking time away from patient care.1 The modifications in codes for asthma were especially far-reaching, and these changes are particularly … |
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