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Increased Incidence of Comorbid Bipolar Disorder and Asthma
Psychiatry Advisor Patients with bipolar disorder and those with asthma have significantly increased comorbidity rates, according to a meta-analysis published in Medicine, suggesting that clinicians should pay extra attention to the link, particularly in older patients.1 … |
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Combining COPD Therapies Aids Older Adults with Comorbid Asthma
Pharmacy Times Unlike previous trials, this study allowed COPD patients with comorbid asthma to participate. This comorbidity is common, as most statistics report that up to one-third of COPD patients also have asthma. Ultimately, those with both COPD and asthma … Better Outcomes For COPD Patients Related to LABAs and ICSs |
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Gastroesophageal Reflux Symptoms and Comorbid Asthma and Posttraumatic Stress Disorder Following the 9/11 Terrorist Attacks on World Trade Center in New York City.
Am J Gastroenterol. 2011 Sep 6;
Authors: Li J, Brackbill RM, Stellman SD, Farfel MR, Miller-Archie SA, Friedman S, Walker DJ, Thorpe LE, Cone J
Abstract
OBJECTIVES:Excess gastroesophageal reflux disease (GERD) was reported in several populations exposed to the September 11 2001 (9/11) terrorist attacks on the World Trade Center (WTC). We examined new onset gastroesophageal reflux symptoms (GERS) since 9/11 and persisting up to 5-6 years in relation to 9/11-related exposures among the WTC Health Registry enrollees, and potential associations with comorbid asthma and posttraumatic stress disorder (PTSD).METHODS:This is a retrospective analysis of 37,118 adult enrollees (i.e., rescue/recovery workers, local residents, area workers, and passersby in lower Manhattan on 9/11) who reported no pre-9/11 GERS and who participated in two Registry surveys 2-3 and 5-6 years after 9/11. Post-9/11 GERS (new onset since 9/11) reported at first survey, and persistent GERS (post-9/11 GERS reported at both surveys) were analyzed using log-binomial regression.RESULTS:Cumulative incidence was 20% for post-9/11 GERS and 13% for persistent GERS. Persistent GERS occurred more often among those with comorbid PTSD (24%), asthma (13%), or both (36%) compared with neither of the comorbid conditions (8%). Among enrollees with neither asthma nor PTSD, the adjusted risk ratio (aRR) for persistent GERS was elevated among: workers arriving at the WTC pile on 9/11 (aRR=1.6; 95% confidence interval (CI) 1.3-2.1) or working at the WTC site > 90 days (aRR=1.6; 1.4-2.0); residents exposed to the intense dust cloud on 9/11 (aRR=1.5; 1.0-2.3), or who did not evacuate their homes (aRR=1.7; 1.2-2.3); and area workers exposed to the intense dust cloud (aRR=1.5; 1.2-1.8).CONCLUSIONS:Disaster-related environmental exposures may contribute to the development of GERS. GERS may be accentuated in the presence of asthma or PTSD.Am J Gastroenterol advance online publication, 6 September 2011; doi:10.1038/ajg.2011.300.
PMID: 21894225 [PubMed – as supplied by publisher]
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