Tag: Concept

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[Updating the concept of asthma. Is asthma a syndrome?].

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[Updating the concept of asthma. Is asthma a syndrome?].

Rev Alerg Mex. 2015 Apr-Jun;62(2):134-41

Authors: Muñoz-López F

Abstract
Several symptoms are common to different processes that affect the respiratory system and their precise assessment is key to a correct diagnosis. Amongst those symptoms, mostly dyspnoea oriented toward the possible diagnosis of asthma. Nevertheless, the concept of asthma has changed in recent times, as inflammation of the bronchial tree is valued as the pathogenic base of the process, although it can not be ignored that the bronchial hyperresponsiveness is still the basis of dyspnoea crisis. In the last years, several variants have been established, being defined as phenotypes and endotypes that can identify diverse asthmatic or pseudo-asthmatic processes, and there for it is questioned if asthma is not the only process, but a syndrome. In any case, it cannot be ignored that dyspnoea episodes can be based on bronchial hyperresponsiveness of genetic origin or due to inflammation because of unfavourable environmental conditions, as well as physical exercise or the ingestión of aspirin, processes in which other mechanisms are involved.

PMID: 25958377 [PubMed – in process]

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The concept of control of COPD in clinical practice.

The concept of control of COPD in clinical practice.

Int J Chron Obstruct Pulmon Dis. 2014;9:1397-405

Authors: Soler-Cataluña JJ, Alcázar-Navarrete B, Miravitlles M

Abstract
Treatment of chronic obstructive pulmonary disease (COPD) requires a personalized approach according to the clinical characteristics of the patients, the level of severity, and the response to the different therapies. Furthermore, patients with the same level of severity measured by the degree of airflow obstruction or even with multidimensional indices may have very different symptoms and limitations for daily activities. The concept of control has been extensively developed in asthma but has not been defined in COPD. Here, we propose a definition of COPD control based on the concepts of impact and stability. Impact is a cross-sectional concept that can be measured by questionnaires such as the COPD Assessment Test or the Clinical COPD Questionnaire. Alternatively, impact can be assessed by the degree of dyspnea, the use of rescue medication, the level of physical activity, and sputum color. Stability is a longitudinal concept that requires the absence of exacerbations and deterioration in the aforementioned variables or in the COPD Assessment Test or Clinical COPD Questionnaire scores. Control is defined by low impact (adjusted for severity) and stability. The concept of control in COPD can be useful in the decision making regarding an increase or decrease in medication in the stable state.

PMID: 25548521 [PubMed – in process]

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Chronic Rhino-Sinusitis and Asthma: Concept of Unified Airway Disease (UAD) and its Impact in Otolaryngology.

Chronic Rhino-Sinusitis and Asthma: Concept of Unified Airway Disease (UAD) and its Impact in Otolaryngology.

Indian J Otolaryngol Head Neck Surg. 2013 Aug;65(Suppl 2):338-42

Authors: Meena RS, Meena D, Aseri Y, Singh BK, Verma PC

Abstract
The aim of our study is to understand the concept of unified airway disease, to know the advantage of this concept in the diagnosis and treatment of allergic rhinitis, chronic rhino-sinusitis and asthma, to know its impact on practice of otolaryngologists, to motivate the otorhinolaryngologist to apply this concept in diagnosis and treatment. This article is based on our experience on (20 cases) chronic rhino-sinusitis and asthma, and observations and results from various literatures. Implement of the concept of unified airway disease and ability to translate its principles into successful diagnostic and treatment strategies can enhance the practice of otolaryngology. The end result is the potential for improved patient care. In our study 80% cases have reduced frequency of symptoms and all (100%) cases having improved night time symptoms thus the use of short-acting beta2 agonist to control the asthma symptoms decreases.

PMID: 24427673 [PubMed]

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