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Conditions: Pneumonia; Bronchiolitis; Asthma; Croup; Upper Respiratory Tract Infection; Lower Respiratory Tract Infection
Intervention: Other: Recording of Infants and Children’s Cough Sounds
Sponsors: ResApp Health Limited; Massachusetts General Hospital; The Cleveland Clinic; Texas Children’s Hospital
Not yet recruiting – verified November 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Bronchial Asthma
Intervention: Drug: budesonide 160?g/formoterol 4.5?g
Sponsor: Zhujiang Hospital
Recruiting – verified July 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Objective measurement of frequency and pattern of nocturnal cough in children with asthma exacerbation.
Ann Allergy Asthma Immunol. 2016 Jun 30;
Authors: Hirai K, Enseki M, Tabata H, Nukaga M, Matsuda S, Kato M, Furuya H, Mochizuki H
Abstract
BACKGROUND: Although a number of patients with asthma report experiencing persistent cough during sleep, it has not yet been objectively investigated.
OBJECTIVE: To classify cough severity and evaluate a characteristic pattern of cough frequency in children with asthma using an objective cough monitoring system.
METHODS: An objective cough monitoring system that specialized in children was used to measure cough frequency and nocturnal cough patterns. Coughs were recorded with microphone and accelerometer and analyzed using a customized software program. The number of nocturnal coughs and the pattern of cough frequency in 30-minute intervals were measured along with the severity of each asthma exacerbation, and the results were compared with children without asthma.
RESULTS: The total overnight cough count of 34 children with asthma was higher than that of 15 children without asthma (P < .001). The total overnight cough count in children with severe asthma exacerbation was higher than that in children with moderate asthma exacerbation (P < .05). The cough counts were significantly increased at the time of falling asleep and waking. This pattern was not observed in children without asthma. The total cough counts and cough patterns in children with asthma were not affected by sex, age, cause of asthma exacerbation, or therapy.
CONCLUSION: Our data indicate huge cough counts and characteristic nocturnal cough patterns in children with asthma. Objective and precise cough monitoring is useful for the management of childhood asthma.
PMID: 27372657 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
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Asthma control predicted by ambulatory cough monitoring
Healio “Data from this study suggest objective measurements of cough provide unique information about asthma control, not fully captured by Asthma Control Questionnaire (ACQ) or Global Initiative for Asthma (GINA) questionnaires,” Paul A. Marsden, MD PhD … |
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fox13now.com |
Could your winter cough be asthma?
fox13now.com In early January 2015, a 48 year old man came in for evaluation of a chronic, dry cough. The cough had begun about 8 weeks earlier after a particularly bad 'cold', and although the nasal and sinus symptoms had resolved, the cough persisted. The patient … |
View full post on asthma – Google News
| Related Articles |
Respiratory disease in the Asia-Pacific region: Cough as a key symptom.
Allergy Asthma Proc. 2016 Jan 21;
Authors: Cho SH, Ghoshal AG, Lin HC, Muttalif AR, Thanaviratananich S, Bagga S, Faruqi R, Sajjan S, Brnabic AJ, Dehle FC, Wang DY
Abstract
BACKGROUND: Respiratory diseases represent a significant impact on health care. A cross-sectional, multicountry (India, Korea, Malaysia, Singapore, Taiwan, and Thailand) observational study was conducted to investigate the proportion of adult patients who received care for a primary diagnosis of asthma, allergic rhinitis (AR), chronic obstructive pulmonary disease (COPD), or rhinosinusitis.
OBJECTIVE: To determine the proportion of patients who received care for asthma, AR, COPD, and rhinosinusitis, and the frequency and main symptoms reported.
METHODS: Patients ages greater than or equal to 18 years, who presented to a physician with symptoms that met the diagnostic criteria for a primary diagnosis of asthma, AR, COPD, or rhinosinusitis were enrolled. Patients and physicians completed a survey that contained questions related to demographics and respiratory symptoms.
RESULTS: A total of 13,902 patients with a respiratory disorder were screened, of whom 7030 were eligible and 5250 enrolled. The highest percentage of patients who received care had a primary diagnosis of AR (14.0% [95% confidence interval {CI}, 13.4 -14.6%]), followed by asthma (13.5% [95% CI, 12.9 -14.1%]), rhinosinusitis (5.4% [95% CI, 4.6 -5.3%]), and COPD (4.9% [95% CI, 5.0 -5.7%]). Patients with a primary diagnosis of COPD (73%), followed by asthma (61%), rhinosinusitis (59%), and AR (47%) most frequently reported cough as a symptom. Cough was the main reason for seeking medical care among patients with a primary diagnosis of COPD (43%), asthma (33%), rhinosinusitis (13%), and AR (11%).
CONCLUSION: Asthma, AR, COPD, and rhinosinusitis represent a significant proportion of respiratory disorders in patients who presented to health care professionals in the Asia-Pacific region, many with concomitant disease. Cough was a prominent symptom and the major reason for patients with respiratory diseases to seek medical care.
PMID: 26802834 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
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Regulation of cough by neuronal Na(+)-K(+) ATPases.
Curr Opin Pharmacol. 2015 Jun 2;22:140-145
Authors: Canning BJ, Farmer DG
Abstract
The Na(+)-K(+) ATPases play an essential role in establishing the sodium gradients in excitable cells. Multiple isoforms of the sodium pumps have been identified, with tissue and cell specific expression patterns. Because the vagal afferent nerves regulating cough must be activated at sustained high frequencies of action potential patterning to achieve cough initiation thresholds, it is a certainty that sodium pump function is essential to maintaining cough reflex sensitivities in health and in disease. The mechanisms by which Na(+)-K(+) ATPases regulate bronchopulmonary vagal afferent nerve excitability are reviewed as are potential therapeutic strategies targeting the sodium pumps in cough.
PMID: 26048736 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Cough
Interventions: Drug: Procaterol; Drug: Placebo
Sponsors: Mahidol University; Thai Otsuka Pharmaceutical Co.,Ltd.
Not yet recruiting – verified January 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Indian Express |
Does your child suffer from recurrent cough and cold? It could be a sign of asthma
TheHealthSite New Delhi, Nov 25: A medical expert from the capital city said that children with recurrent cough, cold and wheeze should visit their physician as these are clear symptoms that the child may be suffering from asthma. He further said that in many of the … 'Recurrent cough and cold in children are signs of asthma' Recurrent cough and cold in children are signs of asthma |
View full post on asthma – Google News
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'Recurrent cough and cold in children are signs of asthma'
Odisha Sun Times “However, if the child continues to have recurrent symptoms till the age of 12-14 years, it is a reason to worry for the parents and the child needs serious medication for asthma,” said S.K. Kabra, a senior paediatrician at the All India Institute of … |
View full post on asthma – Google News