Researchers using iPhones to collect data on Parkinson’s, asthma, other ills … – Fox Business


Fox Business

Researchers using iPhones to collect data on Parkinson's, asthma, other ills
Fox Business
In this July 2, 2015 photo, asthma sufferer Elizabeth Ortiz, who uses the Asthma Health smartphone app daily to track her condition, poses for photos at her apartment, on New York's Lower East Side. Ortiz measures her lung power each day by breathing
Researchers using iPhones to collect data on Parkinson's, asthma, other ills Newser

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Regeneron and Sanofi Announce Positive Pivotal Phase 2b Dupilumab Data in … – Benzinga

Regeneron and Sanofi Announce Positive Pivotal Phase 2b Dupilumab Data in
Benzinga
Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today shared positive results from an interim analysis of a pivotal Phase 2b study of dupilumab in adult patients with moderate-to-severe asthma, who are uncontrolled despite treatment with …

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Asthma app study data on ResearchKit shows mixed results for patient … – MedCity News


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Asthma app study data on ResearchKit shows mixed results for patient
MedCity News
The company, a spin-off of LifeMap Sciences, noted that preliminary data for Asthma Health showed that more than half of users “not only complete the e-consent process, they also come back the very next day to use the app. This is a very high rate of

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Data quality from a longitudinal study of adolescent health at schools near industrial livestock facilities.

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Data quality from a longitudinal study of adolescent health at schools near industrial livestock facilities.

Ann Epidemiol. 2015 Mar 18;

Authors: Guidry VT, Gray CL, Lowman A, Hall D, Wing S

Abstract
PURPOSE: Longitudinal designs enable examination of temporal relationships between exposures and health outcomes, but extended participation can cause study fatigue. We present an approach for analyzing data quality and study fatigue in a participatory, longitudinal study of adolescents.
METHODS: Participants (n = 340) in the Rural Air Pollutants and Children’s Health study completed daily diaries for 3 to 5 weeks in 2009 while we monitored outdoor pollutant concentrations. We used regression models to examine established associations between disease, symptoms, anthropometrics, and lung function as indicators of internal consistency and external validity. We modeled temporal trends in data completeness, lung function, environmental odors, and symptoms to assess study fatigue.
RESULTS: Of 5728 records, 94.2% were complete. Asthma and allergy status were associated with asthma-related symptoms at baseline and during follow-up, for example, prevalence ratio = 8.77 (95% confidence interval: 4.33-17.80) for awakening with wheeze among diagnosed asthmatics versus nonasthmatics. Sex, height, and age predicted mean lung function. Plots depicting outcome reporting over time and associated linear trends showed time-dependent declines for most outcomes.
CONCLUSIONS: We achieved data completeness, internal consistency, and external validity, yet still observed study fatigue, despite efforts to maintain participant engagement. Future investigators should model time trends in reporting to monitor longitudinal data quality.

PMID: 25935712 [PubMed – as supplied by publisher]

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Montefiore and Einstein researchers to present data on obesity, asthma and … – News-Medical.net


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Montefiore and Einstein researchers to present data on obesity, asthma and
News-Medical.net
Researchers from the Children's Hospital at Montefiore (CHAM) and Albert Einstein College of Medicine will present data from more than 50 studies that explore topics including obesity, asthma and autism at the annual meeting of the Pediatric Academic …
Despite guidelines, half of children with asthma do not receive a management planHealio

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Boehringer Presents New Phase III Data for Asthma Therapy Tiotropium – Lung Disease News

Boehringer Presents New Phase III Data for Asthma Therapy Tiotropium
Lung Disease News
Boehringer Ingelheim Pharmaceutical company Boehringer Ingelheim recently presented encouraging data regarding its investigational drug tiotropium delivered through the company's Respimat inhaler, for the treatment of asthma. The data was presented …
Tiotropium improves lung function in asthma, regardless of allergic statusHealio

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New Phase III Data in Asthma Patients Show Tiotropium Improves Lung Function … – PR Newswire (press release)

New Phase III Data in Asthma Patients Show Tiotropium Improves Lung Function
PR Newswire (press release)
HOUSTON, Feb. 21, 2015 /PRNewswire/ — Boehringer Ingelheim today presented data on investigational tiotropium delivered via Respimat® inhaler from five Phase III trials from the UniTinA-asthma® program at the 2015 American Academy of Allergy, …

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AstraZeneca gets some upbeat asthma data to back would-be IL-5 blockbuster – FierceBiotech

AstraZeneca gets some upbeat asthma data to back would-be IL-5 blockbuster
FierceBiotech
Benralizumab–an IL-5 antibody–reduced the rate of asthma exacerbations, hitting the primary endpoint in the trial, says AstraZeneca ($AZN). But the study flagged weak results for the low end of the doses used in the trial, with the top dose doing
AstraZeneca share price: Novel drug shows positive results for severe asthmaiNVEZZ
AstraZeneca's benralizumab succeeds in severe asthmaPharmaTimes

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Investigators use EHR data to study off-label use of asthma medications – AAP News (subscription)

Investigators use EHR data to study off-label use of asthma medications
AAP News (subscription)
Investigators are using electronic health record (EHR) data to look at how common it is for children to be prescribed drugs off-label to treat asthma as well as side effects of such medication use. The study uses de-identified EHR data from the AAP

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