Related Articles |
Asthma and cesarean delivery.
J Pediatr. 2016 Sep;176:221-4
Authors: Schooling CM
PMID: 27568254 [PubMed – in process]
View full post on pubmed: asthma
Related Articles |
Asthma and cesarean delivery.
J Pediatr. 2016 Sep;176:221-4
Authors: Schooling CM
PMID: 27568254 [PubMed – in process]
View full post on pubmed: asthma
Condition: Asthma
Intervention: Other: Experimental: Standard e-AT Intervention
Sponsors: University of Utah; Patient Centered Outcome Research Institute
Recruiting – verified April 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Related Articles |
siRNA Delivery to the Lung: What’s New?
Adv Drug Deliv Rev. 2014 Jun 4;
Authors: Merkel OM, Rubinstein I, Kissel T
Abstract
RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration routes have been adopted for more successful in vivo RNAi. This paper reviews nucleic acid modifications, nanocarrier chemistry, animal models used in successful pulmonary siRNA delivery, as well as clinical translation approaches. We summarize what has been published recently and conclude with the potential problems that may still hamper the efficient clinical application of RNAi in the lung.
PMID: 24907426 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Getting Effective Delivery from Your Asthma Inhaler: What Parents of …
Seaside Courier (BPT) – Did you know that Asthma affects approximately 26 million Americans, including 7.1 million children? May is Asthma and Allergy Awareness month and the perfect time to remind parents of asthmatics about the importance of making sure their child … |
View full post on asthma – Google News
Getting Effective Delivery from Your Asthma Inhaler: What Parents of …
ScoopSanDiego.com (BPT) – Did you know that Asthma affects approximately 26 million Americans, including 7.1 million children? May is Asthma and Allergy Awareness month and the perfect time to remind parents of asthmatics about the importance of making sure their child … |
View full post on asthma – Google News
New Manufacturing Method Improves Drug Delivery of Asthma Inhalers
Pharmaceutical Technology Magazine (blog) A chemical engineering team from Monash University in Australia developed a method to manufacture ultrafine particles that will improve the consistency and efficiency of drugs used in metered-dose inhalers to treat asthma, the University announced in a … |
View full post on asthma – Google News
Condition: Asthma
Interventions: Other: Noninvasive ventilation; Device: Jet nebulizer; Device: The vibrating mesh nebulizer (VMN)
Sponsors: Universidade Federal de Pernambuco; Universidade Federal de Pernambuco
Completed – verified December 2012
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Asthma may boost risk of preterm delivery
Health24.com The study found a 5.4% rate of preterm birth among 13 261 mothers with asthma, compared to 4.4% in 111,931 non-asthmatic mothers. The risk was particularly increased in women with exacerbations of their asthma during pregnancy. Mothers with asthma … |
View full post on asthma – Google News
Related Articles |
On-off pulsed oral drug-delivery systems: a possible tool for drug delivery in chronotherapy.
Ther Deliv. 2011 Sep;2(9):1199-214
Authors: Tran TH, Lee BJ
Abstract
Circadian rhythms regulate most body functions and are important factors to consider when administering drugs. The existence of circadian rhythms in nature and their influences on human biological systems have given rise to the concept of chronotherapy, which is the science of delivering drugs in a synchronized manner with the rhythm-dependent circadian variation inherent in the human body. The safety and efficacy of a drug can be improved by matching the peak plasma concentration during a 24 h period of the rhythms. An on-off pulsed (pulsatile or time-controlled) release drug-delivery system offers rapid and transient release; stepwise release; and the sustained release of a certain amount of drug within a short time period after a predetermined off-release period according to the circadian rhythm of disease states. These systems deliver the drug at the right time and at an appropriate dosage and are the best approach for chronotherapy. These systems show promise for the optimal therapy of chronic diseases such as asthma, hypertension, myocardial infarction and arthritis, which show a circadian dependency. Various technologies have been adopted to mimic circadian rhythms in physiological functions and diseases. This review focuses on the basic concept of circadian rhythm, chronotherapy and recent advances in the development of on-off pulsed oral drug-delivery systems for optimal therapy.
PMID: 22833913 [PubMed – in process]
View full post on pubmed: asthma
Experiences of community pharmacists involved in the delivery of a …
7thSpace Interactive (press release) This paper reports pharmacists'feedback as providers of a Pharmacy Asthma Management Service (PAMS), a trial coordinated across four academic research … |
View full post on asthma – Google News