Breathe Well Live Well
Condition: Peanut Allergy
Interventions: Biological: AR101 powder provided in capsules & sachets; Biological: Placebo powder provided in capsules & sachets
Sponsor: Aimmune Therapeutics, Inc.
Recruiting – verified December 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Desensitization to ceftaroline in a patient with multiple medication hypersensitivity reactions.
Am J Health Syst Pharm. 2015 Feb 1;72(3):198-202
Authors: Jones JM, Richter LM, Alonto A, Leedahl DD
Abstract
PURPOSE: The case of a patient with multiple medication hypersensitivity reactions and a methicillin-resistant Staphylococcus aureus (MRSA) infection who underwent desensitization to ceftaroline is reported.
SUMMARY: A 32-year-old Caucasian woman with asthma, gastroesophageal reflux disease, heart murmur, and major depression was admitted for MRSA cellulitis with a subcutaneous abscess along the left sternomanubrial joint and clavicular osteomyelitis secondary to port placement after gastric bypass surgery. The patient had an extensive history of hypersensitivity reactions. Pertinent documented allergies were as follows: penicillin (anaphylaxis), daptomycin (anaphylaxis), vancomycin (hives), linezolid (hives), ertapenem (rash), ciprofloxacin (rash), and tigecycline (rash). The patient also reported previous reactions to aztreonam (unknown) and gentamicin (hives). The pharmacy was consulted to develop a desensitization protocol for ceftaroline. The desensitization protocol used three serial dilutions of ceftaroline to make 14 sequential infusions with escalating doses. Intramuscular epinephrine, i.v. diphenhydramine, and i.v. methylprednisolone were ordered as needed for the development of immediate hypersensitivity reactions during or after administration of ceftaroline. The cumulative dose (574.94 mg) was administered intravenously over 225 minutes with no breakthrough symptoms reported during or after the desensitization protocol. Ceftaroline fosamil 600 mg i.v. every 12 hours was continued for six weeks.
CONCLUSION: Desensitization to ceftaroline was conducted for a patient with extensive history of hypersensitivity reactions to other drugs, including penicillin-induced anaphylaxis. Desensitization and subsequent treatment with full doses of ceftaroline were accomplished without apparent adverse effects.
PMID: 25596602 [PubMed – in process]
View full post on pubmed: asthma
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Successful Rapid Desensitization for Allergic Dermatitis to Cattle.
Dermatitis. 2014 Nov 8;
Authors: Morgan M
PMID: 25384231 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Drug Allergy
Intervention: Drug: Omalizumab
Sponsors: Dana-Farber Cancer Institute; Novartis Pharmaceuticals
Not yet recruiting – verified April 2014
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Science Codex |
Asthma drug accelerates desensitization in patients with food allergies to …
News-Medical.net An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford shows. Food allergy nearly doubles among black children New Findings of the Benefits of Allergy Immunotherapy Show Implications for … Cases of food allergy 'have doubled in black children' |
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Asthma drug aids simultaneous desensitization to several food allergies, study …
Scope (blog) An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford shows. |
View full post on asthma – Google News
Drug Discovery & Development |
Asthma Drug Aids Simultaneous Desensitization to Food Allergies
Drug Discovery & Development Patients who took the asthma drug omalizumab became desensitized to multiple food allergens, including nuts An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by … Asthma drug aids simultaneous desensitization to several food allergies, study … Asthma drug helps relieve food allergies, study finds Asthma Drug Helped Desensitize Body to Food Allergies at a Faster Rate |
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Counsel & Heal |
Asthma drug aids simultaneous desensitization to several food allergies, study …
Medical Xpress An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford shows. Asthma drug helps relieve food allergies, study finds Asthma Drug Helped Desensitize Body to Food Allergies at a Faster Rate Omalizumab Aids Desensitization to Several Food Allergies |
View full post on asthma – Google News
Counsel & Heal |
Asthma drug aids simultaneous desensitization to several food allergies, study …
EurekAlert (press release) STANFORD, Calif. — An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital … Asthma drug helps relieve food allergies, study finds Asthma Drug Helped Desensitize Body to Food Allergies at a Faster Rate Omalizumab Aids Desensitization to Several Food Allergies |
View full post on asthma – Google News
 Charlotte Observer |
Desensitization is new allergy strategy
The Wenatchee World Online But new tactics are emerging to help children become desensitized to milk, including one reported last month at the annual meeting of the American Academy of Allergy, Asthma and Immunology in San Francisco. Desensitization involves giving someone tiny … Some Cities Are Worse For Allergies Why do more of us have allergies, asthma? Study ranks worst US cities for allergy sufferers |
View full post on asthma – Google News