Was the Doctor Right About Your Child’s Asthma Diagnosis? – U.S. News & World Report


U.S. News & World Report

Was the Doctor Right About Your Child's Asthma Diagnosis?
U.S. News & World Report
It seems like a eureka moment – and it may, in fact, be just that: Your child, who has been nursing a cough and wheezing while exerting himself, is finally diagnosed – with asthma. Historically, research finds this common chronic respiratory disease

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Dyspnea (shortness of breath) in asthma, COPD is important for diagnosis – Bel Marra Health

Dyspnea (shortness of breath) in asthma, COPD is important for diagnosis
Bel Marra Health
Dyspnea (shortness of breath) in asthma, COPD is important for diagnosis Dyspnea (shortness of breath) is found in asthma and COPD and is an important symptom for diagnosis. Shortness of breath severity can range from person to person, but is commonly …

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Volatile organic compounds in asthma diagnosis: a systematic review and meta-analysis.

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Volatile organic compounds in asthma diagnosis: a systematic review and meta-analysis.

Allergy. 2015 Oct 17;

Authors: Cavaleiro Rufo J, Madureira J, Oliveira Fernandes E, Moreira A

Abstract
We aimed to assess the value and classification rate of exhaled volatile organic compounds (VOCs) in asthma diagnosis. A PRISMA oriented systematic search for published studies regarding exhaled VOCs in asthma diagnosis was conducted based on pre-defined criteria. Studies presenting sensitivity and specificity values for the test were included in the meta-analysis. Pooled diagnosis odds ratios (DOR), area under the curve (AUC) and positive and negative likelihood ratios (LR) for exhaled VOC profiles were calculated; and publication bias, threshold effect and heterogeneity were estimated. Eighteen studies were selected for the qualitative analysis and 6 met the criteria for inclusion in the quantitative analysis. Mean (95%CI) pooled DOR, positive and negative LR were 49.3 (15.9 to 153.3), 5.86 (3.07 to 11.21) and 0.16 (0.10 to 0.26), respectively. The AUC value was 0.94. Only 3 of the 18 reviewed studies performed an external validation of the model using a different dataset. The results from the revised studies suggest that exhaled VOCs are promising biomarkers for asthma diagnosis and that several compounds, mainly alkanes, may be significantly associated with asthma inflammation. However, there are still various constraints associated with standardization and externally validated studies are needed to introduce exhaled VOCs profiling in a clinical scenario. This article is protected by copyright. All rights reserved.

PMID: 26476125 [PubMed – as supplied by publisher]

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Parents becoming frustrated at reluctant asthma diagnosis in babies urged not … – Daily Mail


Daily Mail

Parents becoming frustrated at reluctant asthma diagnosis in babies urged not
Daily Mail
With wheezing very common in young children, diagnosis presents a challenge to doctors and many specialists are reluctant to give a diagnosis of asthma and focus on the treatment – and that is why the word asthma wasn't mentioned in Charli's case.

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