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Treatment of asthma: predicting the future of atopic disease treatment Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 2.
Pol Arch Med Wewn. 2016 Dec 23;126(12):1031-1032
Authors: O’Byrne P, Jaeschke R
PMID: 28010009 [PubMed – in process]
View full post on pubmed: asthma
Allergic Skin Disease and the Practicing Allergist: Growing Unmet Need, New Science, and New Treatments.
Immunol Allergy Clin North Am. 2017 Feb;37(1):xiii-xiv
Authors: Tilles SA
PMID: 27886914 [PubMed – in process]
View full post on pubmed: asthma
Conditions: Pneumonia; Bronchiolitis; Asthma; Croup; Upper Respiratory Tract Infection; Lower Respiratory Tract Infection
Intervention: Other: Recording of Infants and Children’s Cough Sounds
Sponsors: ResApp Health Limited; Massachusetts General Hospital; The Cleveland Clinic; Texas Children’s Hospital
Not yet recruiting – verified November 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Sickle Cell Disease
Interventions: Drug: Azithromycin; Other: Placebo
Sponsor: Vanderbilt University
Recruiting – verified November 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Th1/Th2 Immune Balance and Other T Helper Subsets in IgG4-Related Disease.
Curr Top Microbiol Immunol. 2016 Oct 16;
Authors: Moriyama M, Nakamura S
Abstract
IgG4-related disease (IgG4-RD) is a systemic disease characterized by elevated serum IgG4 levels and a strong infiltration of IgG4-positive plasma cells in various organs. IgG4-RD patients also frequently suffer from allergic diseases, including asthma and atopic dermatitis. It is well known that T helper type 2 (Th2) cells have an important role in the initiation of allergic diseases, and Th2 cytokines such as interleukin (IL)-4 and IL-13 promote class switching to IgG4. Therefore, IgG4-RD is considered to be a Th2-predominant disease. However, other Th subsets, including regulatory T cells and T follicular helper cells, have recently received increasing attention with regard to the pathogenesis of IgG4-RD. Exploring the interconnected network of Th subsets in IgG4-RD is a highly promising field of investigation. In this review, we focus on the localization and functions of individual Th subsets to clarify the involvement of these cells in the pathogenesis of IgG4-RD.
PMID: 27744510 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: COPD
Intervention: Other: No intervention
Sponsor: Chinese University of Hong Kong
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Conditions: Asthma; Pulmonary Disease, Chronic Obstructive
Intervention:
Sponsors: University of Leicester; University Hospitals, Leicester
Recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Asthma
Intervention: Other: Smoking
Sponsors: Université de Montréal; Teva Pharmaceuticals USA
Not yet recruiting – verified July 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Conditions: Chronic Obstructive Pulmonary Disease; Bronchial Asthma; Interstitial Lung Disease
Interventions: Device: multiple breath washout test (MBW); Device: impulse oscillometry (IOS); Device: body plethysmography (BP); Device: quantitative computed tomography (qCT)
Sponsor: Universitätsmedizin Mannheim
Recruiting – verified July 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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LINX®, a Novel Treatment for Patients With Refractory Asthma Complicated by Gastroesophageal Reflux Disease
Medscape Background: Gastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma. Current management includes gastric acid suppression therapy and … |
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