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Dexamethasone for asthma in the ER: Better compliance, nearly equal effectiveness
Science Daily Adults with asthma who were treated with one-dose dexamethasone in the emergency department had only slightly higher relapse than patients who were treated with a 5-day course of prednisone. "Enhanced compliance and convenience may support the … |
View full post on asthma – Google News
EurekAlert (press release) |
Dexamethasone for asthma in the ER: Better compliance, nearly equal effectiveness American College of Emergency …
EurekAlert (press release) WASHINGTON –Adults with asthma who were treated with one-dose dexamethasone in the emergency department had only slightly higher relapse than patients who were treated with a 5-day course of prednisone. "Enhanced compliance and convenience … |
View full post on asthma – Google News
Conditions: Health Care Quality, Access, and Evaluation; Insurance, Health
Intervention: Other: HMI
Sponsor: Chulalongkorn University
Not yet recruiting – verified February 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Stuff.co.nz |
New asthma research raises questions about steroid inhalers' effectiveness
Stuff.co.nz Some adolescent asthma sufferers could be relying on ineffective treatment, with new research suggesting steroid inhalers don't work for everyone. Massey University's Centre for Public Health Research led an international study, which discovered for … |
View full post on asthma – Google News
Condition: Tinea
Interventions: Drug: Ketoconazole + betamethasone dipropionate; Drug: Clotrimazole + Dexamethasone acetate
Sponsor: Ache Laboratorios Farmaceuticos S.A.
Not yet recruiting – verified October 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
News-Medical.net |
Researchers compare effectiveness of combination therapy for black patients …
News-Medical.net Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 … Asthma: LABA + Steroids Not a Winning Combo for Blacks Is One Combination Tx Better than Another in Reducing Asthma Exacerbations in … |
View full post on asthma – Google News
Condition: Asthma
Interventions: Drug: Vitamin D3; Drug: Vitamin D3
Sponsor: Hospital General Naval de Alta Especialidad
Not yet recruiting – verified October 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Study Tests Effectiveness of Omalizumab in Treating Perennial Severe Allergic …
Lung Disease News Asthma is a common chronic condition of the airways that is complex and characterized by variable and regular symptoms, airflow obstruction, bronchial hyper responsiveness and inflammation. Asthma may be classified clinically on the basis of various … |
View full post on asthma – Google News
Effect of Common Comparators in Indirect Comparison Analysis of the Effectiveness of Different Inhaled Corticosteroids in the Treatment of Asthma.
PLoS One. 2015;10(3):e0120836
Authors: Kunitomi T, Hashiguchi M, Mochizuki M
Abstract
PURPOSE: Indirect comparison (IC) and direct comparison (DC) of four inhaled corticosteroid (CS) treatments for asthma were conducted, and the factors that may influence the results of IC were investigated. Among those factors, we focused on the effect of common comparator selection in the treatment of asthma, where little control group bias or placebo effect is expected.
METHOD: IC and DC were conducted using the change from baseline in forced expiratory volume in 1 s (FEV1(L)) as an outcome parameter. Differences between inhaled CS were evaluated to compare the results of IC and DC. As a common comparator for IC, placebo (PLB) or mometasone (MOM) was selected. Whether the results of IC are affected by the selection of a common comparator and whether the results of IC and DC are consistent were examined.
RESULTS: 23 articles were identified by a literature search. Our results showed that ICs yielded results similar to DCs in the change from baseline of FEV1(L). No statistically significant difference was observed in inconsistency analysis between ICs and DCs. It was clinically and statistically confirmed that ICs with PLB and those with MOM did not differ in terms of the results of FEV1(L) analysis in this dataset.
CONCLUSION: This study demonstrated that ICs among inhaled CS can deliver results consistent with those of DCs when using the change from baseline in FEV1(L) as an outcome parameter in asthma patients. It was also shown that using an active comparator has similar results if there is no effect of control group bias. It should be emphasized that the investigation of control group bias is a key factor in conducting relevant ICs so that an appropriate common comparator can be selected.
PMID: 25793900 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Asthma
Intervention: Behavioral: Pharmacist intervention and pharmacist support
Sponsor: The Leeds Teaching Hospitals NHS Trust
Completed – verified February 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days