Condition: Asthma
Intervention: Device: Positive Expiratory Pressure
Sponsor: University of Vermont
Not yet recruiting – verified February 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
An Efficacy and Safety Study of Reslizumab Subcutaneous in Patients With Oral Corticosteroid Dependent Asthma and Elevated Blood Eosinophils
Conditions: Asthma; Elevated Blood Eosinophils
Interventions: Drug: Reslizumab; Drug: Placebo
Sponsor: Teva Branded Pharmaceutical Products, R&D Inc.
Not yet recruiting – verified July 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Researchers Use Reduced Airflow, Elevated Exhaled Nitric Oxide to Identify … – Lung Disease News
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Researchers Use Reduced Airflow, Elevated Exhaled Nitric Oxide to Identify …
Lung Disease News In this study, the research team showed that individuals with severe uncontrolled asthma should be re-examined frequently to decrease exacerbations and to identify patients with constant airflow limitation. Asthma is a chronic lung disease … |
View full post on asthma – Google News
Asthma patients showed elevated sputum neutrophils when exposed to … – Healio
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Asthma patients showed elevated sputum neutrophils when exposed to …
Healio Sputum neutrophils were elevated in adults diagnosed with severe asthma and exposed to workplace asthmagens, according to a recent study in BMC Pulmonary Medicine. “We found that approximately one-third of adults with poorly controlled asthma had … |
View full post on asthma – Google News
New Study: Childhood Asthma and Lung Disease Elevated Near Airports – WCVB Boston
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New Study: Childhood Asthma and Lung Disease Elevated Near Airports
WCVB Boston Living next to an airport can be bothersome—from the noise of airplanes taking off and landing to the extra traffic caused by cars carrying people to and from their flights. A recent report from the Massachusetts Department of Public Health offers up … |
View full post on asthma – Google News
Childhood asthma, lung disease elevated near airport, study finds – Boston Globe
Boston Globe |
Childhood asthma, lung disease elevated near airport, study finds
Boston Globe Children who live in neighborhoods bordering Logan International Airport are as much as four times more likely to wheeze, experience shortness of breath, and exhibit other signs of undiagnosed asthma compared to children who live farther away … Study Released On Health Impacts Of Logan Airport Health Study on Impacts of Logan Airport out Today |
View full post on asthma – Google News
Elevated eosinophil levels increased risk for asthma exacerbation – Healio
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Elevated eosinophil levels increased risk for asthma exacerbation
Healio Adults with persistent asthma who had elevated eosinophil levels were at increased risk for exacerbations, according to research presented at the 2014 American Thoracic Society International Conference in San Diego. “Eosinophils are known to be … Elevated blood eosinophil levels find to be risk factor for exacerbations in … Eosinophils linked to worsening asthma |
View full post on asthma – Google News
Elevated blood eosinophil levels are a risk factor for asthma exacerbations – EurekAlert (press release)
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Elevated blood eosinophil levels are a risk factor for asthma exacerbations
EurekAlert (press release) ATS 2014, SAN DIEGO ? In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society … |
View full post on asthma – Google News
Elevated blood eosinophil levels are a risk factor for asthma exacerbations – Medical Xpress
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Elevated blood eosinophil levels are a risk factor for asthma exacerbations
Medical Xpress In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference. |
View full post on asthma – Google News
Elevated Serum IgE against MGL_1304 in Patients with Atopic Dermatitis and Cholinergic Urticaria.
| Related Articles |
Elevated Serum IgE against MGL_1304 in Patients with Atopic Dermatitis and Cholinergic Urticaria.
Allergol Int. 2014 Jan 25;
Authors: Hiragun M, Hiragun T, Ishii K, Suzuki H, Tanaka A, Yanase Y, Mihara S, Haruta Y, Kohno N, Hide M
Abstract
Background: MGL_1304 secreted by Malassezia globosa is contained in human sweat and induces histamine release from basophils in patients with atopic dermatitis (AD) at a high positive rate. The aims of this study were to establish the enzyme-linked immunosorbent assay (ELISA) measuring specific immunoglobulins against MGL_1304 and to investigate the levels of these immunoglobulins in sera of patients with various allergic diseases. Methods: Purified MGL_1304 from human sweat (QRX) and recombinant MGL_1304 (rMGL_1304) were prepared for ELISA. To quantify the amount of MGL_1304-specific immunoglobulins, the standard serum was created by pooling sera of 20 patients with AD whose basophils released histamine in response to QRX. A monoclonal antibody which exhibited the highest neutralizing ability against QRX was established as Smith-2, and used as a capture antibody for the assay of QRX-specific IgE. A total of 156 subjects [normal controls (n = 23), AD (n = 63), cholinergic urticaria (CU) (n = 24), bronchial asthma (n = 32), and allergic rhinitis (n = 14)] were enrolled in this study. Results: ELISA methods to quantify the specific IgE, IgG and IgG4 against MGL_1304 in sera were successfully established. Levels of QRX-specific IgE in sera of patients with AD and CU were significantly higher than those of normal controls. Moreover, the levels of QRX-specific IgE and rMGL_1304-specific IgE in patients with AD were significantly correlated with their disease severities. Conclusions: These ELISA methods to quantify the specific immunoglobulins against MGL_1304 are easy and useful means to assess allergy to MGL_1304. MGL_1304 contained in sweat is an important antigen for patients with AD and CU.
PMID: 24457815 [PubMed – as supplied by publisher]
View full post on pubmed: asthma