Emergency Medicine: Gender must play a role in treating asthma – Columbus Dispatch


Columbus Dispatch

Emergency Medicine: Gender must play a role in treating asthma
Columbus Dispatch
There was no doubt that Carrie, who is obese and a smoker, was experiencing a shortness of breath, and that she had some scattered wheezing in her lungs consistent with an asthma attack. But her oxygen level was normal and she was able to speak in full …

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Gender and age affect the levels of exhaled nitric oxide in healthy children.

Gender and age affect the levels of exhaled nitric oxide in healthy children.

Exp Ther Med. 2013 Apr;5(4):1174-1178

Authors: Zhang H, Shu L, Cai X, Wang Z, Jiao X, Liu F, Hou P, Wang L, Shan L, Chen N, Shang Y

Abstract
Asthma is a chronic inflammatory disorder of the lung and diagnosis is difficult in children. The measurement of fractional exhaled nitric oxide (FeNO) may be useful in the diagnosis and monitoring of treatments. A number of factors affect FeNO levels and their influence varies across countries and regions. This study included 300 healthy students, aged from 6 to 14 years, who participated voluntarily. A comprehensive medical survey was used and measurements of FeNO levels and spirometric parameters were recorded in Shenyang, China. We observed that the median FeNO was 11 ppb (range, 8-16 ppb) in children from the northern areas of China. For males, the median level was 13 ppb (range, 9-18 ppb) and the median level was 10 ppb (range, 8-14 ppb) for females. There was a significant difference between males and females (P= 0.007) and age was correlated with FeNO (R(2)= 0.6554), while weight, height, body mass index (BMI), forced vital capacity (FVC), forced expiratory volume (FEV1), FEV1/FVC and peak expiratory flow (PEF) had no correlation with FeNO. In conclusion, the median FeNO is 11 ppb (range, 8-16 ppb) in male and female healthy children from northern areas of China and is affected by gender and age.

PMID: 23596487 [PubMed – as supplied by publisher]

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Children’s Risk of Allergy Doubles From Same Gender Parents – Counsel & Heal


TopNews United States

Children's Risk of Allergy Doubles From Same Gender Parents
Counsel & Heal
According to Professor Hasan Arshad, a consultant in allergy and immunology at Southampton General Hospital, allergies such as asthma and eczema are gender related and not simply hereditary. "We have known for decades that allergy runs in the family
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Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort.

Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort.

Thorax. 2012 Feb 14;

Authors: Leynaert B, Sunyer J, Garcia-Esteban R, Svanes C, Jarvis D, Cerveri I, Dratva J, Gislason T, Heinrich J, Janson C, Kuenzli N, de Marco R, Omenaas E, Raherison C, Gómez Real F, Wjst M, Zemp E, Zureik M, Burney PG, Anto JM, Neukirch F

Abstract
BackgroundAlthough women with severe non-allergic asthma may represent a substantial proportion of adults with asthma in clinical practice, gender differences in the incidence of allergic and non-allergic asthma have been little investigated in the general population.MethodsGender differences in asthma prevalence, reported diagnosis and incidence were investigated in 9091 men and women randomly selected from the general population and followed up after 8-10 years as part of the European Community Respiratory Health Survey. The protocol included assessment of bronchial responsiveness, IgE specific to four common allergens and skin tests to nine allergens.ResultsAsthma was 20% more frequent in women than in men over the age of 35 years. Possible under-diagnosis of asthma appeared to be particularly frequent among non-atopic individuals, but was as frequent in women as in men. The follow-up of subjects without asthma at baseline showed a higher incidence of asthma in women than in men (HR 1.94; 95% CI 1.40 to 2.68), which was not explained by differences in smoking, obesity or lung function. More than 60% of women and 30% of men with new-onset asthma were non-atopic. The incidence of non-allergic asthma was higher in women than in men throughout all the reproductive years (HR 3.51; 95% CI 2.21 to 5.58), whereas no gender difference was observed for the incidence of allergic asthma.ConclusionsThis study shows that female sex is an independent risk factor for non-allergic asthma, and stresses the need for more careful assessment of possible non-allergic asthma in clinical practice, in men and women.

PMID: 22334535 [PubMed – as supplied by publisher]

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Could Differences In Lung Defects Be Linked To Gender? – Medical News Today (press release)

Could Differences In Lung Defects Be Linked To Gender?
Medical News Today (press release)
Researchers from the University of Wisconsin have raised questions about whether differences in lung defects could be linked to gender in a study presented at the 2011 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI).
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