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Dallas Morning News (blog) |
Practice bubble flattened, Jimmy's 'asthma field' comment … Valley Ranch chock full of Cowboys history
Dallas Morning News (blog) Dallas Cowboys Executive Vice President, CEO, and Director of Player Personnel Stephen Jones (right) and head coach Jason Garrett visit in the hall before a news conference about their first round pick, Ohio St. running back Ezekiel Elliott, at Valley … |
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Human Metapneumovirus Infection is Associated with Severe Respiratory Disease in Preschool Children with History of Prematurity.
Pediatr Neonatol. 2015 May 23;
Authors: Pancham K, Sami I, Perez GF, Huseni S, Kurdi B, Rose MC, Rodriguez-Martinez CE, Nino G
Abstract
BACKGROUND: Human metapneumovirus (HMPV) is a recently discovered respiratory pathogen of the family Paramyxoviridae, the same family as that of respiratory syncytial virus (RSV). Premature children are at high risk of severe RSV infections, however, it is unclear whether HMPV infection is more severe in hospitalized children with a history of severe prematurity.
METHODS: We conducted a retrospective analysis of the clinical respiratory presentation of all polymerase chain reaction-confirmed HMPV infections in preschool-age children (?5 years) with and without history of severe prematurity (<32 weeks gestation). Respiratory distress scores were developed to examine the clinical severity of HMPV infections. Demographic and clinical variables were obtained from reviewing electronic medical records.
RESULTS: A total of 571 preschool children were identified using polymerase chain reaction-confirmed viral respiratory tract infection during the study period. HMPV was identified as a causative organism in 63 cases (11%). Fifty-eight (n = 58) preschool-age children with HMPV infection were included in this study after excluding those with significant comorbidities. Our data demonstrated that 32.7% of children admitted with HMPV had a history of severe prematurity. Preschool children with a history of prematurity had more severe HMPV disease as illustrated by longer hospitalizations, new or increased need for supplemental O2, and higher severity scores independently of age, ethnicity, and history of asthma.
CONCLUSION: Our study suggests that HMPV infection causes significant disease burden among preschool children with a history of prematurity leading to severe respiratory infections and increasing health care resource utilization due to prolonged hospitalizations.
PMID: 26117550 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
News-Medical.net |
Men with a history of asthma less likely to have aggressive prostate cancer
News-Medical.net In what they are calling a surprising finding in a large study of men who completed questionnaires and allowed scientists to review their medical records, Johns Hopkins researchers report that men with a history of asthma were less likely than those … Does asthma protect against lethal prostate cancer? |
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Condition: Asthma
Intervention:
Sponsor: National Institute of Environmental Health Sciences (NIEHS)
Recruiting – verified November 2014
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Medical History, Lifestyle, Family History, and Occupational Risk Factors for Marginal Zone Lymphoma: The InterLymph Non-Hodgkin Lymphoma Subtypes Project.
J Natl Cancer Inst Monogr. 2014 Aug;2014(48):52-65
Authors: Bracci PM, Benavente Y, Turner JJ, Paltiel O, Slager SL, Vajdic CM, Norman AD, Cerhan JR, Chiu BC, Becker N, Cocco P, Dogan A, Nieters A, Holly EA, Kane EV, Smedby KE, Maynadié M, Spinelli JJ, Roman E, Glimelius B, Wang SS, Sampson JN, Morton LM, de Sanjosé S
Abstract
BACKGROUND: Marginal zone lymphoma (MZL), comprised of nodal, extranodal, and splenic subtypes, accounts for 5%-10% of non-Hodgkin lymphoma cases. A detailed evaluation of the independent effects of risk factors for MZL and its subtypes has not been conducted.
METHODS: Data were pooled from 1052 MZL cases (extranodal [EMZL] = 633, nodal [NMZL] = 157, splenic [SMZL] = 140) and 13766 controls from 12 case-control studies. Adjusted unconditional logistic regression was used to compute odds ratios (ORs) and 95% confidence intervals (CIs).
RESULTS: Novel findings for MZL subtypes include increased risk for B-cell activating autoimmune conditions (EMZL OR = 6.40, 95% CI = 4.24 to 9.68; NMZL OR = 7.80, 95% CI = 3.32 to 18.33; SMZL OR = 4.25, 95% CI = 1.49 to 12.14), hepatitis C virus seropositivity (EMZL OR = 5.29, 95% CI = 2.48 to 11.28), self-reported peptic ulcers (EMZL OR = 1.83, 95% CI = 1.35 to 2.49), asthma without other atopy (SMZL OR = 2.28, 95% CI = 1.23 to 4.23), family history of hematologic cancer (EMZL OR = 1.90, 95% CI = 1.37 to 2.62) and of non-Hodgkin lymphoma (NMZL OR = 2.82, 95% CI = 1.33 to 5.98), permanent hairdye use (SMZL OR = 6.59, 95% CI = 1.54 to 28.17), and occupation as a metalworker (NMZL OR = 3.56, 95% CI = 1.67 to 7.58). Reduced risks were observed with consumption of any alcohol (EMZL fourth quartile OR = 0.48, 95% CI = 0.28 to 0.82) and lower consumption of wine (NMZL first to third quartile ORs < 0.45) compared with nondrinkers, and occupation as a teacher (EMZL OR = 0.58, 95% CI = 0.37 to 0.88).
CONCLUSION: Our results provide new data suggesting etiologic heterogeneity across MZL subtypes although a common risk of MZL associated with B-cell activating autoimmune conditions was found.
PMID: 25174026 [PubMed – in process]
View full post on pubmed: asthma
Condition: Aspirin Exacerbated Respiratory Disease (AERD)
Interventions: Drug: Ifetroban, Oral Capsule; Drug: Placebo, Oral Capsule
Sponsor: Cumberland Pharmaceuticals
Active, not recruiting – verified August 2014
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Non-Smokers With History of Asthma Sought for Medical Study
The Ledger If CPAP, which stands for continued positive airway pressure, improves asthma by relaxing airways, that could mean less need for inhalers and use of inhaled rescue medications. USF is one of 18 centers in the American Lung Association Asthma Clinical … |
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Boston police search for missing 13-year-old; boy has asthma history and no medication
According to Boston.com Boston police are looking for the public’s help in finding a 13-year-old boy who has been missing since Tuesday afternoon.
LaRue Henderson has a history of asthma and does not have his medication, police said in a statement.
He went missing from his Dorchester home at about 1 p.m. Tuesday.
LaRue was last seen wearing a dark blue “puffy” coat with a fur collar and the “Mecca” brand name on the back, a gray thermal shirt, blue jeans and white Nike sneakers with a red swoosh and black trim.
For additional information and a photo visit Boston.com
The boy has been in the city for two months and does not know the area, police said.
Police asked anyone with information on the boy’s whereabouts call 911 or the Area B-2 detectives at 617-343-4275.
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Obesity and Family History May Contribute To Increased Risk Of Asthma In …
The AIDS Beacon Results from a recent study suggest that people with HIV are more than twice as likely as the general population to be diagnosed with asthma. The findings indicate that factors such as obesity, allergy-associated inflammation, and a family history of … |
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Use the holidays to collect a family health history
Tbo.com AP From asthma and heart disease to cancer and pregnancy loss, some conditions are more likely to be found among relatives. By MARY SHEDDEN | The Tampa Tribune At family gatherings, relatives can't resist sharing the latest joys and ordeals related to … |
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