Efficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES)

Condition:   Hypereosinophilic Syndrome
Interventions:   Drug: Mepolizumab 300 mg;   Drug: Placebo matching mepolizumab;   Drug: Active OCS capsules (5 mg prednisolone or prednisone);   Drug: Placebo matching OCS capsules
Sponsor:   GlaxoSmithKline
Not yet recruiting – verified July 2016

View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days

Hypereosinophilic syndrome secondary to strongyloides infection: a case of recurrent asthma exacerbations.

Hypereosinophilic syndrome secondary to strongyloides infection: a case of recurrent asthma exacerbations.

BMJ Case Rep. 2013;2013

Authors: Khan WA, Santhanakrishnan K

Abstract
Hypereosinophilic syndrome is a disease characterised by a persistently elevated eosinophil count. The syndrome can be reactive to infections, autoimmune disease, cancers, etc. Multiple organ involvement can occur including cardiomyopathies, pulmonary involvement and neuropathies. We describe a case of a patient who presented with signs and symptoms of asthma with recurrent asthma exacerbations, but in fact proved to be hypereosinophilic syndrome secondary to strongyloides infection.

PMID: 23964035 [PubMed – in process]

View full post on pubmed: asthma