Coroner’s office identifies girl who drowned in pool after asthma attack – Las Vegas Review-Journal


Las Vegas Review-Journal

Coroner's office identifies girl who drowned in pool after asthma attack
Las Vegas Review-Journal
The 12-year-old girl who died after having an asthma attack at a pool in the northeast valley Thursday has been identified by the Clark County coroner's office. Alayzah Marcus was at the Cape Cod Village Apartment pool at 4231 Terrestrial Drive near

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Study identifies new target for severe asthma, chronic inflammatory diseases – Medical Xpress


Medical Xpress

Study identifies new target for severe asthma, chronic inflammatory diseases
Medical Xpress
Chronic inflammation is commonly found in asthma, autoimmune diseases, cancer, and viral infections, and it's characterized by constant activation of platelets with unhealed tissue damage. Scientists who have studied the Dkk-1 protein were aware that

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Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Related Articles

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Nat Genet. 2014 Jun 15;

Authors: Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O’Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ

Abstract
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in 32,917 additional individuals of European ancestry. We found six new regions associated at genome-wide significance (P < 5 × 10(-8)) with FVC in or near EFEMP1, BMP6, MIR129-2-HSD17B12, PRDM11, WWOX and KCNJ2. Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to FVC. Newly implicated regions were followed up in samples from African-American, Korean, Chinese and Hispanic individuals. We detected transcripts for all six newly implicated genes in human lung tissue. The new loci may inform mechanisms involved in lung development and the pathogenesis of restrictive lung disease.

PMID: 24929828 [PubMed – as supplied by publisher]

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Study allegedly identifies immunological connection between obesity and asthma – Lexology (registration)

Study allegedly identifies immunological connection between obesity and asthma
Lexology (registration)
A recent animal study has allegedly identified a new immunological connec- tion between obesity and asthma involving “inflammasome activation and production of cytokine interleukin-17 by innate lymphoid cells in the lung,” according to a concurrent 

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DA Candidate Ken Thompson Identifies Brooklyn Heights as High Asthma Zone – Brooklyn Heights Blog (blog)

DA Candidate Ken Thompson Identifies Brooklyn Heights as High Asthma Zone
Brooklyn Heights Blog (blog)
In his discussion of environmental problems in Brooklyn, he notes that Brooklyn Heights is one of five borough neighborhoods–the others are Bushwick, Downtown Brooklyn, Park Slope, and Williamsburg–having asthma rates that exceed the national
Ken Thompson unveils plans for environmental protection unit at Brooklyn DA's Brooklyn Daily Eagle

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Genome sequencing identifies variants possibly linked to childhood asthma – Bizcommunity.com

Genome sequencing identifies variants possibly linked to childhood asthma
Bizcommunity.com
Scientists at the School of Public Health's Center for Perinatal, Pediatric and Environmental Epidemiology used a technique that sequenced only the small fraction of the genome that codes for proteins and identified tens of thousands of variants in

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Study identifies Olympic athletes with asthma and airway hyper-responsiveness – News-Medical.net

Study identifies Olympic athletes with asthma and airway hyper-responsiveness
News-Medical.net
Based on data from the last five Olympic games, a study by the University of Western Australia has identified those athletes with asthma and airway hyper-responsiveness. With a prevalence of around 8% they are the most common chronic conditions among

and more »

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