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Discovery improves understanding of factors that trigger allergic asthma
News-Medical.net However, if these regulatory mechanisms malfunction the cells of the immune system attack innocuous substances which enter the body from the environment, ultimately leading to the development of atopic diseases such as allergic asthma. In western … |
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Pharmacist Counseling Improves Salbutamol Asthma Treatment
Pharmacy Times By educating nurses, counseling physicians, and providing feedback on inhalation technique, pharmacists can reduce issues related to salbutamol treatment for asthma and bronchitis, according to research findings published in BMC Health Services … |
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Treatment of acute asthma among pregnant women improves over 17-year period
Healio “On the basis of four observational studies of pregnant women with acute asthma in 48 EDs, we found a significant increase in the ED administration of systemic corticosteroids and prescription of systemic corticosteroids at ED discharge over the 17 … |
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Vitamin D improves corticosteroid efficacy and attenuates its side-effects in an animal model of asthma.
Can J Physiol Pharmacol. 2014 Nov 3;:1-9
Authors: Mehta AA, Agrawal AD, Appanna V, Chaudagar KK
Abstract
The subacute use of corticosteroids has side-effects such as glucose intolerance, dyslipidemia, anxiety, and depression, which could be halted with vitamin D, which is an immunomodulatory vitamin. Thus, we aimed to study the anti-asthmatic efficacy and side-effects profile of vitamin D, the corticosteroid dexamethasone, and their combination on ovalbumin-induced airway inflammation in rats. For this, 2 different doses of vitamin D (50 IU/kg, daily for 2 weeks, or and 60000 IU/kg, bolus dose, by intraperitoneal injection (i.p.)) were administered in combination with dexamethasone (2.5 mg/kg, i.p., for 2 weeks) prior to challenge with ovalbumin. At the end of the therapy, the asthmatic parameters such as differential white blood cell counts, serum levels of immunoglobulin E, bronchoalveolar lavaged fluid, and interleukin-5, as well as serum levels of nitric oxide were significantly increased after allergen challenges in asthmatic rats as compared with the controls. Such increases were significantly attenuated by monotherapy with vitamin D and with combination therapy of vitamin D and dexamethasone, where the combination therapy was superior to the monotherapy. Dexamethasone-induced hyperglycemia, hyperlipidemia, and behavioral abnormalities in the allergic rats were attenuated with vitamin D. The daily dose was better for controlling serum levels of immunoglobulin E than the bolus dose, whereas the bolus was superior for reducing dexamethasone-induced psychotropic abnormalities. There were no significant changes in other parameters between the daily and the bolus dose. In conclusion, a daily dose of vitamin D in combination with dexamethasone is more efficacious for treating asthma in allergic rats than monotherapy.
PMID: 25429688 [PubMed – as supplied by publisher]
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KPLU News for Seattle and the Northwest |
In-Home Asthma Treatment Improves Adults' Control
Medscape Low-income adults with uncontrolled asthma had improved control and quality of life when they received five home visits per year by community health workers, according to study results published online November 24 in JAMA Internal Medicine. Home Visits As Helpful As Medicine For King County Asthma Patients Home Visits Can Improve Asthma Control for Low-income Adults |
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Surgery for sleep apnea improves asthma control
UChicago News Researchers from the University of Chicago found that in the first year after the operation, children who had the surgery had a 30 percent reduction in acute asthma exacerbations and a 38 percent decrease in acute status asthmaticus—a medical emergency. |
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Surgery for sleep apnea improves asthma control
Medical Xpress Asthma is a common and costly respiratory disease. It is the third-most prevalent chronic pediatric disease in the United States, affecting an estimated 7.1 million children under the age of 18, according to the Centers for Disease Control and Prevention. |
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Asthma Action Plan Improves Outcomes
Medscape SAN DIEGO — A web-based electronic asthma action plan that incorporates guidelines from the National Heart, Lung and Blood Institute into the Cerner Millennium platform greatly reduces asthma-related visits to the emergency department, oral steroid … |
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Headlines & Global News |
Less Pollution Exposure Improves Asthma Symptoms
Headlines & Global News According to recent article published in Annals of Allergy, Asthma and Immunology; asthma symptoms of a woman improved after her doctor recommended that she take a different, less polluted route to work. The woman had recently moved from a rural … Individuals can improve asthma symptoms by avoiding air pollution Does your child with a food allergy or asthma have an action plan? ACAAI recommends flu vaccine for children with egg allergies, asthma |
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Teva's Asthma Drug 'Significantly' Improves Lung Function In Phase 3 Trials
NASDAQ (RTTNews.com) – Teva Pharmaceutical Industries Ltd. ( TEVA ) Monday said asthma patients with elevated eosinophils showed significant improvement in lung function and asthma control after being treated with reslizumab in final-stage studies of the anti … |
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