A Study to Assess the Effect of Particle Size of AZD7594 on Pharmacokinetics (PK) After a Single Inhaled Dose When Administered Using the Dry Powder Inhaler in Healthy Volunteers.

Condition:   Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Treatment A – AZD7594;   Drug: Treatment B – AZD7594;   Drug: Treatment C – AZD7594
Sponsor:   AstraZeneca
Not yet recruiting – verified October 2016

View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days

A Study to Assess the Effect of Particle Size of AZD7594 on Pharmacokinetics After a Single Inhaled Dose When Administered Using the Dry Powder Inhaler in Healthy Volunteers.

Condition:   Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Treatment A – AZD7594;   Drug: Treatment B – AZD7594;   Drug: Treatment C – AZD7594
Sponsor:   AstraZeneca
Not yet recruiting – verified October 2016

View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days

A 12-week, Randomized, Parallel-Group, Proof-of-Concept Study of Tulobuterol Patch and Salmeterol Inhaler as Add-on Therapy in Adult-Onset Mild-to-Moderate Asthma.

Related Articles

A 12-week, Randomized, Parallel-Group, Proof-of-Concept Study of Tulobuterol Patch and Salmeterol Inhaler as Add-on Therapy in Adult-Onset Mild-to-Moderate Asthma.

Clin Exp Pharmacol Physiol. 2016 Oct 8;:

Authors: Inoue H, Niimi A, Matsumoto H, Ito I, Oguma T, Otsuka K, Takeda T, Nakaji H, Tajiri T, Iwata T, Nagasaki T, Mishima M

Abstract
Patch formulation of tulobuterol has been used in asthma treatment as a long-acting ?2 -agonist (LABA) through sustained skin absorption. Its treatment efficacy, especially in small airways, remains poorly understood. The study aim was to investigate LABA add-on effects of tulobuterol patch (TP) and salmeterol inhaler (SA) on pulmonary function, asthma control, and health status. Patients who had adult-onset under-controlled asthma, despite taking inhaled corticosteroids, were enrolled in a randomized, open-label, parallel-group, proof-of-concept study of 12-week add-on treatment with TP (n = 16) or SA (n = 17). Spirometry, impulse oscillometry (IOS), exhaled nitric oxide levels, and clinical questionnaires of asthma control, health status (St. George’s Respiratory Questionnaire: SGRQ), and symptoms were evaluated every 4 weeks. Add-on treatment of SA significantly improved the spirometric indices of small airway obstruction (forced expiratory flow between 25% and 75% of FVC: FEF25-75 , and maximum expiratory flow at 25% of FVC: MEF25 ) and IOS indices of whole respiratory resistance (resistance at 5 Hz) as compared to TP. In intra-group comparisons, add-on treatment of TP improved the scores of the asthma control test and the total SGRQ, as well as the symptom and impact components of the SGRQ. SA add-on treatment improved FEV1 and IOS parameters of resistance at 20 Hz and reactance at 5 Hz. Neither of the treatments improved exhaled nitric oxide levels. In conclusion, add-on treatment of TP improved asthma control and health status, whereas SA improved pulmonary function measures associated with large and small airway involvement among patients with adult-onset mild-to-moderate asthma. This article is protected by copyright. All rights reserved.

PMID: 27718262 [PubMed – as supplied by publisher]

View full post on pubmed: asthma

Glenmark Pharma launches digital inhaler for asthma patients – Times of India


Times of India

Glenmark Pharma launches digital inhaler for asthma patients
Times of India
Glenmark Pharmaceuticals Limited, the research-led global integrated pharmaceutical company, launched what the company touted as India's first Digital Dose Inhaler for asthma and pulmonary disease patients. The inhaler, branded as Digihaler, provides …
Glenmark launches digital dose inhaler for asthma patientsMoneycontrol.com
Glenmark's new 'digital dose inhaler' for asthma, COPD displays dose remaining in itTheHealthSite
Glenmark launches 'Digihaler' for asthma and COPD medicationpharmabiz.com

all 4 news articles »

View full post on asthma – Google News

Glenmark launches digital dose inhaler for asthma patients – Moneycontrol.com


Moneycontrol.com

Glenmark launches digital dose inhaler for asthma patients
Moneycontrol.com
"This next-gen inhaler provides accurate digital dose counter along with low dose warning indicator to enable Asthma and chronic obstructive pulmonary disease (COPD) patients to track adherence to their therapy," the Mumbai-based firm said in a statement.

and more »

View full post on asthma – Google News

Glenmark launches electronic inhaler for asthma patients – Hindu Business Line


Hindu Business Line

Glenmark launches electronic inhaler for asthma patients
Hindu Business Line
"In the case of asthma and COPD condition, where daily preventative medication is crucial for its treatment, implication of non-adherence leads to poor control symptoms, worsening the quality of life, high mortality rate which further increases health
Glenmark launches digital dose inhaler for asthma patientsBusiness Standard
Glenmark launches digital inhaler for asthma, obstructive pulmonary diseaseLivemint

all 6 news articles »

View full post on asthma – Google News