Children’s Hospital gets $1.25 million for inner-city asthma research – BizTimes.com (Milwaukee)


BizTimes.com (Milwaukee)

Children's Hospital gets $1.25 million for inner-city asthma research
BizTimes.com (Milwaukee)
“Research shows that asthma disproportionately affects communities of color with devastating impact,” said Ellen Gilligan, president and CEO of the Greater Milwaukee Foundation in a statement announcing the project. “African Americans have the highest …

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Demographics, not location, explain high inner-city asthma rates – Clinical Advisor

Demographics, not location, explain high inner-city asthma rates
Clinical Advisor
“Although it is thought that inner-city areas have a high burden of asthma, the prevalence of asthma in inner cities across the United States is not known,” noted Corinne A. Keet, MD, PHD, of Johns Hopkins University in Baltimore, Maryland, and colleagues.
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Public Release: 20-Jan-2015 Time to rethink the inner-city asthma epidemic? – EurekAlert (press release)

Public Release: 20-Jan-2015 Time to rethink the inner-city asthma epidemic?
EurekAlert (press release)
Challenging the long-standing belief that city dwellers suffer disproportionately from asthma, the results of a new Johns Hopkins Children's Center study of more than 23,000 U.S. children reveal that income, race and ethnic origin may play far more

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?Researchers challenge inner-city asthma theory – CBS News


CBS News

?Researchers challenge inner-city asthma theory
CBS News
Poverty increased the risk of asthma, as did being from certain racial/ethnic groups. Asthma rates were 20 percent for Puerto Ricans, 17 percent for blacks, 10 percent for whites, 9 percent for other Hispanics, and 8 percent for Asians, the study found.
Asthma is not more prevalent in the inner city, researchers sayWashington Post
Big city life may not be a key asthma risk, study findsFox News
Big city life may not be a key asthma risk: studyNew York Daily News
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Guideline-Recommended Fractional Exhaled Nitric Oxide is a Poor Predictor of Health Care Use Among Inner-city Children and Adolescents Receiving Usual Asthma Care.

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Guideline-Recommended Fractional Exhaled Nitric Oxide is a Poor Predictor of Health Care Use Among Inner-city Children and Adolescents Receiving Usual Asthma Care.

Chest. 2013 Jun 13;

Authors: McCormack MC, Aloe C, Curtin-Brosnan J, Diette GB, Breysse PN, Matsui EC

Abstract
ABSTRACT BACKGROUND: Recent American Thoracic Society (ATS) guidelines support use of FENO in patients with asthma and highlight gaps in the evidence base. Little is known about use of FENO to predict asthma exacerbations among high-risk, urban, minority populations receiving usual care. METHODS: 138 children with persistent asthma were enrolled in a prospective observational cohort study and skin tested at baseline (wheal?3mm=+SPT). Fractional exhaled nitric oxide (FENO) levels, lung function, and asthma-related health care use were assessed at baseline and every three months thereafter for one year. Relationships between FENO and health care utilization in the subsequent three months were examined. Final models accounted for repeated outcome measures and were adjusted for age, gender and lung function. RESULTS: The mean age was 11 years (range 5-17), and most were male (57%), African American (91%), and atopic (90%). At baseline, FENO was (median [IQR]: 31.5ppb [16-61]) and FEV1/FVC was (mean ± SD: 80.7±9.6%). There were 237 acute asthma-related health care visits, 105 unscheduled doctor (UD) visits, 125 ED visits, and 7 hospitalizations during the follow-up period. FENO was not a significant predictor of acute visits, ED visits, UD visits, or hospitalization in either unadjusted or adjusted analyses. Use of recommended cutpoints did not improve the predictive value of FENO (PPV 0.6-32.8%), nor did application of the guideline-based algorithm to assess change over time. CONCLUSIONS: FENO may not be a clinically useful predictor of health care use for asthma exacerbations in urban minority children with asthma.

PMID: 23764806 [PubMed – as supplied by publisher]

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