Efficacy in asthma of once-daily treatment with fluticasone furoate: a … – 7thSpace Interactive (press release)

Efficacy in asthma of once-daily treatment with fluticasone furoate: a
7thSpace Interactive (press release)
Methods: Asthma patients maintained on ICS for [greater than or equal to]3 months with baseline morning forced expiratory volume in one second (FEV1) 50-80% of predicted normal value and FEV1 reversibility of [greater than or equal to]12% and [greater

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Prevalence of Asthma Symptoms based on the European Community Respiratory … – 7thSpace Interactive (press release)

Prevalence of Asthma Symptoms based on the European Community Respiratory
7thSpace Interactive (press release)
FENO is increased in patients with asthma. The relationship between subjective asthma symptoms and airway inflammation is an important issue. We expected that the subjective asthma symptoms in women might be different from those in men.

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High Frequency Chest Wall Oscillation for asthma and chronic obstructive … – 7thSpace Interactive (press release)

High Frequency Chest Wall Oscillation for asthma and chronic obstructive
7thSpace Interactive (press release)
The objective of this study was to evaluate the use of HFCWO early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD). Methods: Randomized, multi-center, double-masked phase II clinical trial of

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Treatment of allergic asthma: Modulation of Th2 cells and their responses – 7thSpace Interactive (press release)

Treatment of allergic asthma: Modulation of Th2 cells and their responses
7thSpace Interactive (press release)
Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory response in the airways. It is currently treated and, more or less,

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Adult attention deficit hyperactivity disorder is associated with asthma – 7thSpace Interactive (press release)

Adult attention deficit hyperactivity disorder is associated with asthma
7thSpace Interactive (press release)
Similarly, asthma also has a substantial prevalence among adults. Previous studies concerning a potential relationship between ADHD and asthma have not presented consistent results. Methods: A cross-sectional study of 594 adult patients diagnosed with

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Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta … – 7thSpace Interactive (press release)

Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta
7thSpace Interactive (press release)
Asthma is a phenotypically diverse disease with genetic susceptibility. A single nucleotide polymorphism (SNP) in the CD14 gene at position -260 (also known as -159) C>T has been inconsistently associated with asthma. The aim of this study was to

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The asthma candidate gene NPSR1 mediates isoform specific downstream signalling – 7thSpace Interactive (press release)

The asthma candidate gene NPSR1 mediates isoform specific downstream signalling
7thSpace Interactive (press release)
Neuropeptide S Receptor 1 (NPSR1, GPRA, GPR154) was first identified as an asthma candidate gene through positional cloning and has since been replicated as an asthma and allergy susceptibility gene in several independent association studies.

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In vivo imaging of the airway wall in asthma: Fibered confocal fluorescence … – 7thSpace Interactive (press release)

In vivo imaging of the airway wall in asthma: Fibered confocal fluorescence
7thSpace Interactive (press release)
Airway remodelling is a feature of asthma including fragmentation of elastic fibres observed in the superficial elastin network of the airway wall. Fibered confocal fluorescence microscopy (FCFM) is a new and non-invasive imaging technique performed

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Altered expression of microRNA in the airway wall in chronic asthma: miR-126 … – 7thSpace Interactive (press release)

Altered expression of microRNA in the airway wall in chronic asthma: miR-126
7thSpace Interactive (press release)
In a mouse model, we have previously shown that miRNAs are potentially important therapeutic targets in allergic asthma, because inhibition of miR-126, one of a small subset of miRNAs upregulated in the airway wall, effectively suppressed Th2-driven

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