Breathe Well Live Well
Condition: Asthma
Interventions: Drug: Salbutamol; Procedure: Forced oscillation technique; Procedure: Plethysmography
Sponsor: Central Hospital, Nancy, France
Completed – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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Objective measurement of frequency and pattern of nocturnal cough in children with asthma exacerbation.
Ann Allergy Asthma Immunol. 2016 Jun 30;
Authors: Hirai K, Enseki M, Tabata H, Nukaga M, Matsuda S, Kato M, Furuya H, Mochizuki H
Abstract
BACKGROUND: Although a number of patients with asthma report experiencing persistent cough during sleep, it has not yet been objectively investigated.
OBJECTIVE: To classify cough severity and evaluate a characteristic pattern of cough frequency in children with asthma using an objective cough monitoring system.
METHODS: An objective cough monitoring system that specialized in children was used to measure cough frequency and nocturnal cough patterns. Coughs were recorded with microphone and accelerometer and analyzed using a customized software program. The number of nocturnal coughs and the pattern of cough frequency in 30-minute intervals were measured along with the severity of each asthma exacerbation, and the results were compared with children without asthma.
RESULTS: The total overnight cough count of 34 children with asthma was higher than that of 15 children without asthma (P < .001). The total overnight cough count in children with severe asthma exacerbation was higher than that in children with moderate asthma exacerbation (P < .05). The cough counts were significantly increased at the time of falling asleep and waking. This pattern was not observed in children without asthma. The total cough counts and cough patterns in children with asthma were not affected by sex, age, cause of asthma exacerbation, or therapy.
CONCLUSION: Our data indicate huge cough counts and characteristic nocturnal cough patterns in children with asthma. Objective and precise cough monitoring is useful for the management of childhood asthma.
PMID: 27372657 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Asthma
Intervention:
Sponsors: University of North Carolina, Chapel Hill; American Academy of Allergy, Asthma, and Immunology
Recruiting – verified January 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Lung Disease News |
Asthma Differentiated from COPD Using FENO Measurement
Lung Disease News shutterstock_181677491 Making a differential diagnosis between asthma and chronic obstructive pulmonary disease (COPD) may be as simple as breathing in and breathing out. A research duo from the Departments of Chest and Clinical & Chemical … |
View full post on asthma – Google News
| Related Articles |
Day-to-day measurement of patient-reported outcomes in exacerbations of chronic obstructive pulmonary disease.
Int J Chron Obstruct Pulmon Dis. 2013;8:273-86
Authors: Kocks JW, van den Berg JW, Kerstjens HA, Uil SM, Vonk JM, de Jong YP, Tsiligianni IG, van der Molen T
Abstract
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are a major burden to patients and to society. Little is known about the possible role of day-to-day patient-reported outcomes during an exacerbation. This study aims to describe the day-to-day course of patient-reported health status during exacerbations of COPD and to assess its value in predicting clinical outcomes.
METHODS: Data from two randomized controlled COPD exacerbation trials (n = 210 and n = 45 patients) were used to describe both the feasibility of daily collection of and the day-to-day course of patient-reported outcomes during outpatient treatment or admission to hospital. In addition to clinical parameters, the BORG dyspnea score, the Clinical COPD Questionnaire (CCQ), and the St George’s Respiratory Questionnaire were used in Cox regression models to predict treatment failure, time to next exacerbation, and mortality in the hospital study.
RESULTS: All patient-reported outcomes showed a distinct pattern of improvement. In the multivariate models, absence of improvement in CCQ symptom score and impaired lung function were independent predictors of treatment failure. Health status and gender predicted time to next exacerbation. Five-year mortality was predicted by age, forced expiratory flow in one second % predicted, smoking status, and CCQ score. In outpatient management of exacerbations, health status was found to be less impaired than in hospitalized patients, while the rate and pattern of recovery was remarkably similar.
CONCLUSION: Daily health status measurements were found to predict treatment failure, which could help decision-making for patients hospitalized due to an exacerbation of COPD.
PMID: 23766644 [PubMed – in process]
View full post on pubmed: asthma
 MedPage Today |
F E NO Measurement May Guide Asthma Management in Pregnancy
Medscape September 12, 2011 — Measurement of fraction of exhaled nitric oxide (F E NO) may help guide asthma management in pregnancy, according to the results of a double-blind, parallel-group, randomized controlled trial reported in the September 10 issue of … Algorithm Improves Asthma Care in Pregnancy |
View full post on asthma – Google News