Airway Resistance Measurements Shown to Help Effectively Differentiate … – Lung Disease News


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Airway Resistance Measurements Shown to Help Effectively Differentiate
Lung Disease News
To examine the contribution of RAW and sGAW to a diagnosis of obstructive airways disease and their role in differentiating asthma from COPD, in the study titled “Airways resistance and specific conductance for the diagnosis of obstructive airways

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Serial Lung Function Measurements in Healthy and Mild Asthmatic Adults After Oral Inhalation of Ethanolic Solutions Containing Two Concentrations of the Excipient Butylated Hydroxytoluene (BHT) Administered With the Respimat® B (RMT-B)

Condition:   Asthma
Interventions:   Drug: BHT 0.1%;   Drug: BHT 0.5%;   Drug: Placebo for RMT-B;   Drug: Placebo for HFA-MDI
Sponsor:   Boehringer Ingelheim
Completed – verified August 2014

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Effect of Different Positions on FVC and FEV1 Measurements of Asthmatic Patients.

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Effect of Different Positions on FVC and FEV1 Measurements of Asthmatic Patients.

J Phys Ther Sci. 2014 Apr;26(4):591-3

Authors: Melam GR, Buragadda S, Alhusaini A, Alghamdi MA, Alghamdi MS, Kaushal P

Abstract
[Purpose] The purpose of our study was to investigate the effect of different positions on pulmonary function test (PFT) values such as forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) of asthmatic patients .[Subjects and Methods] Thirty subjects with severe asthma aged between 20-39 years were enrolled after they had signed a written consent. Subjects were selected using the inclusion criteria, and PFT were randomly administered. Spirometer measurements (FVC, FEV1) were taken in the supine, side lying on right, side lying on left, sitting and standing positions. Each measurement was taken three times, and the average values were analyzed. [Results] One- way analysis of variance (ANOVA) and Tukey’s Test (post hoc) for pair- wise comparison indicated that there was a significant difference in the FEV1 values of the asthmatic patients however a significant difference was obtained between standing and supine positions. There was also a significant difference in the FVC values between the standing and supine lying position in the pair -wise comparison. [Conclusion] This study showed standing is the best position for measuring FEV1 and FVC of asthmatic subjects. The more upright the position, the higher the FEV1 and FVC will be.

PMID: 24764640 [PubMed]

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