Modeling COPD and asthma in a human small airway-on-a-chip – Medical Xpress


Medical Xpress

Modeling COPD and asthma in a human small airway-on-a-chip
Medical Xpress
COPD and asthma are inflammatory reactions in the lung which can be dramatically exacerbated by viral and bacterial infections, as well as smoking. It is known that many of the associated disease processes occur in the conducting airway sections of the …

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Modeling COPD and asthma in a human small airway-on-a-chip – EurekAlert (press release)

Modeling COPD and asthma in a human small airway-on-a-chip
EurekAlert (press release)
COPD and asthma are inflammatory reactions in the lung which can be dramatically exacerbated by viral and bacterial infections, as well as smoking. It is known that many of the associated disease processes occur in the conducting airway sections of the …

and more »

View full post on asthma – Google News

A Statistical Modeling Framework for Projecting Future Ambient Ozone and its Health Impact due to Climate Change.

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A Statistical Modeling Framework for Projecting Future Ambient Ozone and its Health Impact due to Climate Change.

Atmos Environ (1994). 2014 Jun 1;89:290-297

Authors: Chang HH, Hao H, Sarnat SE

Abstract
The adverse health effects of ambient ozone are well established. Given the high sensitivity of ambient ozone concentrations to meteorological conditions, the impacts of future climate change on ozone concentrations and its associated health effects are of concern. We describe a statistical modeling framework for projecting future ozone levels and its health impacts under a changing climate. This is motivated by the continual effort to evaluate projection uncertainties to inform public health risk assessment. The proposed approach was applied to the 20-county Atlanta metropolitan area using regional climate model (RCM) simulations from the North American Regional Climate Change Assessment Program. Future ozone levels and ozone-related excesses in asthma emergency department (ED) visits were examined for the period 2041-2070. The computationally efficient approach allowed us to consider 8 sets of climate model outputs based on different combinations of 4 RCMs and 4 general circulation models. Compared to the historical period of 1999-2004, we found consistent projections across climate models of an average 11.5% higher ozone levels (range: 4.8%, 16.2%), and an average 8.3% (range: -7% to 24%) higher number of ozone exceedance days. Assuming no change in the at-risk population, this corresponds to excess ozone-related ED visits ranging from 267 to 466 visits per year. Health impact projection uncertainty was driven predominantly by uncertainty in the health effect association and climate model variability. Calibrating climate simulations with historical observations reduced differences in projections across climate models.

PMID: 24764746 [PubMed – as supplied by publisher]

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IBM, Georgia Tech Point Data Modeling At Kids Health – InformationWeek

IBM, Georgia Tech Point Data Modeling At Kids Health
InformationWeek
Project seeks to identify factors contributing to health outcomes of pediatric patients with asthma, autism, and diabetes. By Marianne Kolbasuk McGee InformationWeek IBM and the Georgia Institute of Technology are launching a new data analysis and
IBM and Georgia Institute of Technology Partner on "One Million Healthy PR Newswire (press release)
IBM, Georgia Institute of Technology form pediatric data partnershipZDNet (blog)

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