Asthmatic children may suffer more from dirty hands – chicagotribune.com – Chicago Tribune

Asthmatic children may suffer more from dirty hands – chicagotribune.com
Chicago Tribune
NEW YORK (Reuters Health) – An arsenal of hand sanitizers, hygiene education and good old-fashioned soap failed to prevent asthma attacks among school children in one Alabama county. For children with asthma, the common cold is the top trigger of

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Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.

Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.

Evid Based Complement Alternat Med. 2012;2012:908562

Authors: Yang YL, Hsu HT, Wang KH, Wang CS, Chen CM, Ko WC

Abstract
Hesperidin is present in the traditional Chinese medicine, “Chen Pi,” and recently was reported to have anti-inflammatory effects. Therefore, we were interested in comparing the effects of hesperidin and hesperidin-3′-O-methylether on phosphodiesterase inhibition and airway hyperresponsiveness (AHR) in a murine model of asthma. In the present results, hesperidin-3′-O-methylether, but not hesperidin, at 30??mol/kg (p.o.) significantly attenuated the enhanced pause (P(enh)) value, suppressed the increases in numbers of total inflammatory cells, macrophages, lymphocytes, neutrophils, and eosinophils, suppressed total and OVA-specific immunoglobulin (Ig)E levels in the serum and BALF, and enhanced the level of total IgG(2a) in the serum of sensitized and challenged mice, suggesting that hesperidin-3′-O-methylether is more potent than hesperidin in suppression of AHR and immunoregulation. The different potency between them may be due to their aglycons, because these two flavanone glycosides should be hydrolyzed by ?-glucosidase after oral administration. Neither influenced xylazine/ketamine-induced anesthesia, suggesting that they may have few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion. In conclusion, hesperidin-3′-O-methylether is more potent in phosphodiesterase inhibition and suppression of AHR and has higher therapeutic (PDE4(H)/PDE4(L)) ratio than hesperidin. Thus, hesperidin-3′-O-methylether may have more potential for use in treating allergic asthma and chronic obstructive pulmonary disease.

PMID: 23082087 [PubMed – in process]

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Stressed hospital workers get admitted more for obesity, depression, asthma – HealthLeaders Media

Stressed hospital workers get admitted more for obesity, depression, asthma
HealthLeaders Media
Hospital employees are less healthy and account for more health care costs than the general population, troubling statistics that have Michigan hospitals rethinking the way they do business. Costs for medical care and prescription drugs were 9 percent

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More than 75% of the Asthma Patient Care Costs Are Attributed to Severe … – Einnews Portugal

More than 75% of the Asthma Patient Care Costs Are Attributed to Severe
Einnews Portugal
Over 150 delegates from more than 30 countries are meeting in Gothenburg, Sweden,at the International Severe Asthma Forum, ISAF, 2012 organised by the European Academy of Allergy and Clinical Immunology, EAACI. ISAF 2012 aims to respond to the

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More than 75% of the Asthma Patient Care Costs Are Attributed to … – Einnews Portugal

More than 75% of the Asthma Patient Care Costs Are Attributed to …
Einnews Portugal
More than 75% of the Asthma Patient Care Costs Are Attributed to … [12 Oct 2012] PR Newswire; Disney's Club Penguin Launches New Interactive Guide to Help Parents … [12 Oct 2012] PR Newswire; Swissvoice Will Present its Full Range of CAT-iq2.0

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Finding allergy relief could be more difficult for Tennesseans under proposed … – Chattanooga Times Free Press

Finding allergy relief could be more difficult for Tennesseans under proposed
Chattanooga Times Free Press
With the sneezing and wheezing season upon us, a national group of allergists and asthma specialists are touting these numbers, and actively opposing proposed legislation that would make over-the-counter medications containing a major meth ingredient

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Childhood asthma may be more closely linked to traffic fumes than previously … – GlobalPost


ScienceBlog.com (blog)

Childhood asthma may be more closely linked to traffic fumes than previously
GlobalPost
Fresh snow blankets the mountains behind the downtown skyline after a series of storms that hammered northern California delivered much needed precipitation to the Greater Los Angeles Area January 7, 2008 in Los Angeles, California. The American Lung
Near-roadway air pollution a major contributor to L,A. asthmaScienceBlog.com (blog)
Roads' impact on asthma underestimatedOnMedica
HEALTH: Freeway pollution risk 'very important,' researcher saysPress-Enterprise
Daily Mail –The Atlantic Cities
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Why Are Asthmatic Youngsters More Likely To Be Bullied? – RedOrbit


Firstpost

Why Are Asthmatic Youngsters More Likely To Be Bullied?
RedOrbit
The inability of asthmatic children to participate in sports, and the melancholy feelings those youngsters experience, are believed to be two of the primary reasons that they are frequently the victims of bullying, researchers from one UK hospital
Asthmatic children more likely to be bulliedTimes of India
Why children with asthma are more likely to be bulliedScienceBlog.com (blog)
Why kids with asthma are likelier to be bulliedDaily News & Analysis
Irish Health
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