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Researchers discover new pathway that may be vital for understanding allergic …
News-Medical.net There has been a great deal of interest in the research community around ILC2 cells and the newly recognised role they play in atopic diseases such as asthma, eczema and hayfever. ILC2 cells produce a molecule called IL-13, which is responsible for … The role of immune cells in asthma |
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New cellular pathway triggering allergic asthma response identified
Medical Xpress Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. |
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New Cellular Pathway Triggering Allergic Asthma Response Identified
UCSD Medical Center Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. |
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| Related Articles |
Natural products and their derivatives regulating the janus kinase/signal transducer and activator of transcription pathway.
J Asian Nat Prod Res. 2014 Jul;16(7):800-12
Authors: Lin Y, Wang F, Zhang GL
Abstract
Janus kinase/signal transducer and activator of transcriptions (JAK/STAT) signaling pathway is one of the major signaling pathways involved in a variety of human physiological and pathological process. The proteins of JAK/STAT pathway or interferon response element (such as JAK, STAT, Src, SOCS, 2’5′-OAS, and ISRE) might be as drug targets for the study of physiological processes and treatment of related diseases, including cell proliferation, differentiation, apoptosis and immune processes, inflammation, cancer, arthritis, asthma, diabetes, and other diseases. This review attempts to summarize the current status of natural products and their derivatives (2002-2013) regulating the proteins or transcription elements of JAK/STAT signaling pathway to supply a new direction or drug targets for the discovery of new drugs.
PMID: 25076196 [PubMed – in process]
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The pathway to asthma winds through Toll-like receptor 4
Your Houston News Asthma is part of a battle that takes place as the immune system marshals its forces to fight off an invading organism-or what mimics such invaders. The ensuing fight takes a significant toll on the human airway and lungs, often generating a violent … |
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The pathway to asthma winds through toll-like receptor 4
Science Codex Asthma is part of a battle that takes place as the immune system marshals its forces to fight off an invading organism-or what mimics such invaders. The ensuing fight takes a significant toll on the human airway and lungs, often generating a violent … |
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BioNews Texas |
BCM Researcher Suggests: The pathway to asthma winds through Toll-like …
BioNews Texas Early studies carried out where mice were given a cocktail of proteinases demonstrated that these enzymes induced an allergic disease response, similar to asthma. Studying the role of proteinases in allergy, Dr. Corry demonstrated that these … |
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The pathway to asthma winds through toll-like receptor 4
EurekAlert (press release) "The core of a computer is its CPU (central processing unit) or chip. We are looking for the chip that drives allergic disease," said the professor of medicine, chief of the section of immunology, allergy and rheumatology in Baylor College of Medicine … |
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Medical Xpress |
Pathway to asthma winds through Toll-like receptor 4
BCM News Asthma is part of a battle that takes place as the immune system marshals its forces to fight off an invading organism-or what mimics such invaders. The ensuing fight takes a significant toll on the human airway and lungs, often generating a violent … Clues emerge to explain allergic asthma Insights into Asthma, And Maybe the Hygiene Hypothesis |
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Medical Xpress |
The pathway to asthma winds through toll-like receptor 4
Medical Xpress Microscope image of fibrin plug in a human asthmatic airway. The fibrin plug is blocking this medium-sized airway's luemn. This condition is termed plastic bronchitis and results from the presence of airway proteinases that cleave the protein … |
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