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Aerospan improved pediatric asthma outcomes, regardless of prior therapy
Healio “The study findings indicate Aerospan is an effective treatment option for patients that require an inhaled steroid, such as those with mild to moderate asthma,” Karafilidis said. “This, coupled with our other data that suggest Aerospan did not … |
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Tiotropium Showing Promise in Pediatric Asthma
Medscape AUSTIN — In children with poorly controlled asthma, once-daily tiotropium delivered with the Respimat inhaler improves lung function when added to inhaled corticosteroids, with no apparent change in adverse effects, new research has shown. The drug … |
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Improving care transitions for pediatric asthma patients
FierceMobileHealthcare (press release) The following is an interview published in the FierceHealthIT eBook "Technology to Enable Care Transitions." Ivor Horn, M.D., an emergency medical physician at Children's National Medical Center in Washington, D.C., has her sights set on creating truly … |
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Health policy expert to present MEDTalk on pediatric asthma alternative …
News from the University of Massachusetts MEDTalk: Pediatric Asthma and Transforming Care for the Most Vulnerable, the third in the Merkin Series on Innovations in Care Delivery, will feature seven TED-style talks in person at the Brookings Intuition's Washington, D.C., headquarters or as a … |
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| Related Articles |
Spink5 And Adrb2 Haplotypes Are Risk Factors For Asthma In Mexican Pediatric Patients.
J Asthma. 2014 Sep 18;:1-23
Authors: Martínez-Aguilar N, Del Río-Navarro B, Navarro-Olivos E, García-Ortíz H, Orozco L, Jiménez-Morales S
Abstract
Abstract Background: Asthma is one of the most common respiratory diseases worldwide, and the complexity of its etiology has been widely documented. Chromosome 5q31-33 is one of the main loci implicated in asthma and asthma-related traits. IL13, CD14, and ADRB2, which are located in this risk locus, are among the genes most strongly associated with asthma susceptibility. Objectives: This study evaluated whether single-nucleotide polymorphisms or haplotypes at 5q31-33 conferred risk for asthma in Mexican-Mestizo pediatric patients. Methods: We performed a case-control study including 851 individuals, 421 of them affected with childhood-onset asthma and 430 ethnically matched unaffected subjects. We used the TaqMan Allelic Discrimination Assay to genotype 20 single-nucleotide polymorphisms within IL5, RAD50, IL13, IL4, CD14, SPINK5, HTR4, ADRB2, and IL12B. Results: Although no association was detected for any risk allele, three SPINK5 haplotypes (GGCT: p= 6 x 10(-6); AATC: p= 0.0001; AGTT: p= 0.0001) and five ADRB2 haplotypes (AGGACC: p=0.0014; AGGAAG: p=0.0002; TGAGAG: p=0.0001; AGGAAC: p=0.0002; AAGGAG: p=0.003) were associated with asthma. Notably, the AGTT SPINK5 haplotype exhibited a male gender-dependent association (p=7.6 x 10(-5)). Conclusion: Our results suggest that SPINK5 and ADRB2 haplotypes might play a role in the susceptibility to childhood-onset asthma.
PMID: 25233048 [PubMed – as supplied by publisher]
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Pediatric Asthma: An Opportunity In Payment Reform And Public Health
Health Affairs (blog) Asthma affects 7 million children – more than 10 percent of kids in the U.S. – and is the most common chronic childhood disease. Yet even with high levels of insurance coverage, 46 percent of pediatric patients have uncontrolled asthma. There are … |
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CBS Local |
Denver Pediatric Allergist: Don't Panic To New Study Linking Childhood Asthma …
CBS Local DENVER (CBS4)- A new study links a pregnant woman's exposure to some common household chemicals to their unborn child's risk of developing asthma. The chemicals, called phthalates, are used in everything from fragrances to food containers. They are … |
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Mobile Pediatric Asthma Program Offered in Texarkana
TXK Today logo_1_201192016626747 Texarkana, Texas – CHRISTUS St. Michael Health System will provide a free Mobile Pediatric Asthma Program for school-age children throughout the month of August. The Spirit of St. Michael and a specially trained staff will offer … |
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Annual Medicaid costs for pediatric asthma-related ED visits topped $270 million
Healio State Medicaid programs spent an estimated $272 million on pediatric asthma-related ED visits in 2010, according to recent CDC data. The researchers estimated state-based costs for asthma-related ED visits among children aged younger than 18 years, … |
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Condition: Asthma
Interventions: Drug: Berodual® Respimat®, low dose; Drug: Berodual® Respimat®, high dose; Drug: Berodual® MDI
Sponsor: Boehringer Ingelheim
Completed – verified July 2014
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