GPS- and WiFi-enabled inhaler to help epidemiologists study asthma – PhysOrg.com


PhysOrg.com

GPS- and WiFi-enabled inhaler to help epidemiologists study asthma
PhysOrg.com
(PhysOrg.com) — Asthma is a serious medical condition that can have life threatening consequences. That is why most asthmatics carry an inhaler. It is small enough to be nestled in a purse, or carried in a pocket, and most asthmatics will not leave

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Children of working moms face more health problems – PhysOrg.com


TheMedGuru

Children of working moms face more health problems
PhysOrg.com
Children of working mothers are significantly more likely to experience health problems, including asthma and accidents, than children of mothers who don't work, according to new research from North Carolina State University.
Kids of working mums at increased risk of falling ill–studyTheMedGuru

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Inhaled corticosteroids effective as rescue medication for asthma – PhysOrg.com


MedIndia

Inhaled corticosteroids effective as rescue medication for asthma
PhysOrg.com
Inhaled corticosteroids, currently recommended as a daily controller medication, can also be an effective rescue treatment for asthma when combined with the standard rescue medication albuterol, according to research at National Jewish Health and other
Alternative Way to Treat Childhood Asthma?WebMD
Asthma may be over-treated in kids: StudyToronto Sun
Health Highlights: Feb. 15, 2011U.S. News & World Report
Doctors Lounge –BBC News –Pulse
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Childhood Asthma Foundation Invests Millions

Childhood Asthma Foundation Invests Millions to Implement Best Practices

Childhood asthma foundation invests millions to implement best practices to manage the disease
November 10th, 2010

The Merck Childhood Asthma Network, Inc. (MCAN), today announced it is targeting four high risk cities with nearly $4 million for programs that will combine evidence-based science, case management and asthma trigger removal plans to manage a disease that requires more than the right medical care. Programs in Chicago, Los Angeles, Philadelphia and San Juan, Puerto Rico – all cities with high rates of childhood asthma – will enroll children and families in the most comprehensive asthma management research program ever designed for the community level.

MCAN’s funding, an investment that will cover a four-year period of enrollment, education, implementation and evaluation, follows previous investments in each of the cities that resulted in positive health outcomes. While still being analyzed, results include decreasing the number of missed school days in half, a decrease in symptom days and an increase in the number of families whose children have asthma action plans.

“When it comes to overcoming the enormous cost, health and personal burdens of childhood asthma, we knew it required more than dusting off the clinical research and parachuting it into different parts of the country. We needed to be there, to see how the research translated on the ground,” said Dr. Floyd Malveaux Executive Director of MCAN and former Dean of the College of Medicine at Howard University. “Our continued community partnerships will reveal the best ways to manage a disease with roots that are both biological and environmental.”

The evidence-based programs allow the different communities to both adhere to rigorous asthma management fundamentals and tailor the approach to meet their particular needs. To evaluate the effectiveness of this approach, researchers at the Center for Managing Chronic Disease at the University of Michigan will lead a cross-site program evaluation and help disseminate findings that could impact public health practices and policies surrounding the management of childhood asthma.

The Addressing Asthma in Englewood Project is based on the Southside of Chicago and is a collaborative effort of the University of Illinois, School of Public Health and the Respiratory Health Association of Metropolitan Chicago. The program centers around a community educator model and links children with asthma to appropriate services, education programs in schools, community groups, and local agencies; and a home visit case management program to enhance asthma education, identification and mitigation of asthma triggers.

In Los Angeles, MCAN is partnering with the LA Unified School District for the “Yes We Can” Children’s Asthma Program in the nation’s second largest school district. The program involves a care coordination and education model that will extend beyond the immediate school clinic to include system changes between health, educational and community settings. The program will triage students and families into the appropriate level of intervention, improve the coordination of care between schools, clinics and community providers, and will focus on measuring symptom reduction and school days missed.

In Philadelphia, the Children’s Hospital of Philadelphia’s You Can Control Asthma Care Coordination Program will utilize asthma health care navigators located within four primary care centers operated by the hospital. Navigators will work with primary care providers as an integral member of the family’s asthma care team assisting families in the identification and reduction of asthma triggers in the home, providing self-management education, and other support and resources for families of high risk children with asthma.

The La Red de Asma Infantil de Merck de Puerto Rico program involves evidence-based interventions as part of an asthma care coordination program across home, health care and community settings. The program will be implemented in the Nemesio Canales Housing Project in San Juan, Puerto Rico by the University of Puerto Rico and RAND Health. “La Red” aims to promote asthma-friendly communities throughout the island of Puerto Rico and to enhance access to quality asthma healthcare for this highly vulnerable and underserved community.

According to Dr. Malveaux, one of the keys to moving forward and making broad, systemic change, will be to demonstrate the results, disseminate the approaches and sustain the important work MCAN’s partners are achieving in their communities.

“While the health improvements we have seen to date in individual communities have been overwhelmingly positive, the real potential lies in the ability to make the lessons learned applied as broadly as possible, to help as many children with asthma as possible,” Dr. Malveaux said. “Long term and wide spread change is the goal of our next phase of work.”

Provided by The Merck Childhood Asthma Network, Inc.

Childhood Asthma and Antibiotic use Link?

Research team investigates whether antibiotic use triggers childhood asthma and allergies

Study looks at how intestinal bacteria changes in newborns after babies take antibiotics, and whether changes trigger certain medical conditions

A cross-Canada team of medical researchers suspects that giving antibiotics to infants in their first year of life may be the underlying trigger that causes asthma and allergies to develop later in childhood.

The researchers, from five Canadian universities, are conducting a major, $2.5-million study on how intestinal bacteria changes in newborns after the babies take antibiotics, and whether those changes trigger certain medical conditions in children. The researchers include microbiologists, epidemiologists and immunologists.

Anita Kozyrskyj, who is co-lead investigator in this new federally funded study, demonstrated in a pilot study that infants who receive antibiotics by three months of age have changes in their microbiota.

“The number of different kinds of bacteria is less,” says Kozyrskyj, a researcher in the Faculty of Medicine & Dentistry at the University of Alberta.

“Now the question is: does antibiotic use early in life change the microbiota in the intestines of children? And are these changes associated with the development of asthma and allergies in children? We are hoping to specifically pinpoint which ‘bad’ bacteria it is that is causing asthma.”

Everyone has “good” intestinal bacteria, known as microbiota, to help absorb nutrients and protect against harmful bacteria. No one is born with this; it develops throughout the first year of life. Normal development of the microbiota can be affected by various factors such as caesarean-section delivery and infant diet and medication use. By one year of age, more than 50 per cent of Canadian infants will receive an antibiotic prescription.

Studies have shown that antibiotics affect the microbiota. As well, composition of microbiota in children who have allergies is different than the microbiotia in children who don’t suffer from allergies, as demonstrated by previous research studies.

Her research will zero in on antibiotic use in the first year of life and will be conducted through a research group called SyMBIOTA, or Synergy in Microbiota Research. The SyMBIOTA team includes researchers Piush Mandhane, Dean Befus, Radha Chari and Catherine Field.

Her colleagues from the University of Toronto, co-principal investigator James Scott and researcher David Guttman, will look at the composition of microbiota from fecal samples from children aged three months and at one year; this will involve about 2,500 babies from across the Prairies and the West Coast. By extracting DNA from these samples, researchers will be able to identify the bacteria that are present in microbiota.

Tatiana Celemin’s four-month-old baby, Sara, is taking part in the research study. Celemin’s son has asthma and that is one of the key reasons the family wanted to get involved with the study—to help researchers find out more about the condition.

“Even if it doesn’t have an impact on Sara, I think it’s important for the medical research to be there to hopefully impact future generations of children.”

This research is funded by the Canadian Institutes of Health Research and the AllerGen Network Centres of Excellence.

Kozyrskyj, an epidemiologist, is an associate professor of pediatrics at the U of A, and the Women and Children’s Health Research Institute research chair in maternal-child health and the environment.