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Ahdoot: Air pollution triggers asthma attacks; Clean Power Plan will reduce both
Roanoke Times Rates of asthma, like food allergy, are increasing. The underlying cause of both of these conditions is unknown. It is well known, however, that certain irritants, including cigarette smoke, hay fever and air pollution, cause asthma attacks. |
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AIR POLLUTION: EPA foes turned asthma study into weapon for ozone fight
Environment & Energy Publishing When a Johns Hopkins University researcher published a study showing race and income as risk factors for asthma, she started getting phone calls from industry groups opposing U.S. EPA's bid to tighten the national ozone standard. Dr. Corinne Keet said … |
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| Related Articles |
Ambient air pollution, lung function, and airway responsiveness in asthmatic children.
J Allergy Clin Immunol. 2015 Jun 29;
Authors: Ierodiakonou D, Zanobetti A, Coull BA, Melly S, Postma DS, Boezen HM, Vonk JM, Williams PV, Shapiro GG, McKone EF, Hallstrand TS, Koenig JQ, Schildcrout JS, Lumley T, Fuhlbrigge AN, Koutrakis P, Schwartz J, Weiss ST, Gold DR, Childhood Asthma Management Program Research Group
Abstract
BACKGROUND: Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthmatic patients are lacking.
OBJECTIVE: We sought to investigate pollution effects in a longitudinal asthma study and effect modification by controller medications.
METHODS: We examined associations of lung function and methacholine responsiveness (PC20) with ozone, carbon monoxide (CO), nitrogen dioxide, and sulfur dioxide concentrations in 1003 asthmatic children participating in a 4-year clinical trial. We further investigated whether budesonide and nedocromil modified pollution effects. Daily pollutant concentrations were linked to ZIP/postal code of residence. Linear mixed models tested associations of within-subject pollutant concentrations with FEV1 and forced vital capacity (FVC) percent predicted, FEV1/FVC ratio, and PC20, adjusting for seasonality and confounders.
RESULTS: Same-day and 1-week average CO concentrations were negatively associated with postbronchodilator percent predicted FEV1 (change per interquartile range, -0.33 [95% CI, -0.49 to -0.16] and -0.41 [95% CI, -0.62 to -0.21], respectively) and FVC (-0.19 [95% CI, -0.25 to -0.07] and -0.25 [95% CI, -0.43 to -0.07], respectively). Longer-term 4-month CO averages were negatively associated with prebronchodilator percent predicted FEV1 and FVC (-0.36 [95% CI, -0.62 to -0.10] and -0.21 [95% CI, -0.42 to -0.01], respectively). Four-month averaged CO and ozone concentrations were negatively associated with FEV1/FVC ratio (P < .05). Increased 4-month average nitrogen dioxide concentrations were associated with reduced postbronchodilator FEV1 and FVC percent predicted. Long-term exposures to sulfur dioxide were associated with reduced PC20 (percent change per interquartile range, -6% [95% CI, -11% to -1.5%]). Treatment augmented the negative short-term CO effect on PC20.
CONCLUSIONS: Air pollution adversely influences lung function and PC20 in asthmatic children. Treatment with controller medications might not protect but rather worsens the effects of CO on PC20. This clinical trial design evaluates modification of pollution effects by treatment without confounding by indication.
PMID: 26187234 [PubMed – as supplied by publisher]
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Erie Media |
I blamed China's air pollution for my asthma, and I was wrong
Quartz My chest x-ray was normal but I took a breathing test which showed my lung function only 60% of normal, and she said I probably had asthma. I'll never forget those moments after taking those first two puffs of albuterol: in just a few minutes, that … Residential Air Purifiers Market in China to Grow at a CAGR of 10.24% over the … |
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Port pollution cleanup partially credited with fewer child asthma-related …
The Daily Breeze Coexisting with refineries, freeways and the congested, behemoth twin port complex, the South Bay and Harbor Area are home to a relatively high number of asthma sufferers. “We have a lot more than other areas even though we live near the beach and the … |
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NDTV |
World Asthma Day: Air Pollution in Indian Cities Can Trigger Asthma
NDTV World Asthma Day: Air Pollution in Indian Cities Can Trigger Asthma World Asthma Day is celebrated every year on May 5 in an attempt to increase awareness about asthma. It's organized by the Global Initiative for Asthma (GINA) and this year the theme … Rising pollution triggering asthma in healthy people |
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Times of India |
Pollution triggering asthma in healthy people
Times of India Asthma is a chronic disorder of the lungs, where inflammation and narrowing of the airways happen. And when the air is polluted the allergens present like smoke, dust, toxic gases like carbon monoxide and nitro-oxide affect asthma patients with … Rising pollution triggering asthma in healthy people (May 5 is World Asthma Day) |
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Chronic disease prevalence in women and air pollution – A 30-year longitudinal cohort study.
Environ Int. 2015 Apr 6;80:26-32
Authors: To T, Zhu J, Villeneuve PJ, Simatovic J, Feldman L, Gao C, Williams D, Chen H, Weichenthal S, Wall C, Miller AB
Abstract
BACKGROUND: Air pollution, such as fine particulate matter (PM2.5), can increase risk of adverse health events among people with heart disease, diabetes, asthma and chronic obstructive pulmonary disease (COPD) by aggravating these conditions. Identifying the influence of PM2.5 on prevalence of these conditions may help target interventions to reduce disease morbidity among high-risk populations.
OBJECTIVES: The objective of this study is to measure the association of exposure of PM2.5 with prevalence risk of various chronic diseases among a longitudinal cohort of women.
METHODS: Women from Ontario who enrolled in the Canadian National Breast Screening Study (CNBSS) from 1980 to 1985 (n=29,549) were linked to provincial health administrative data from April 1, 1992 to March 31, 2013 to determine the prevalence of major chronic disease and conditions (heart disease, diabetes, asthma, COPD, acute myocardial infarction, angina, stroke and cancers). Exposure to PM2.5 was measured using satellite data collected from January 1, 1998 to December 31, 2006 and assigned to resident postal-code at time of entry into study. Poisson regression models were used to describe the relationship between exposure to ambient PM2.5 and chronic disease prevalence. Prevalence rate ratios (PRs) were estimated while adjusting for potential confounders: baseline age, smoking, BMI, marital status, education and occupation. Separate models were run for each chronic disease and condition.
RESULTS: Congestive heart failure (PR=1.31, 95% CI: 1.13, 1.51), diabetes (PR=1.28, 95% CI: 1.16, 1.41), ischemic heart disease (PR=1.22, 95% CI: 1.14, 1.30), and stroke (PR=1.21, 95% CI: 1.09, 1.35) showed over a 20% increase in PRs per 10?g/m(3) increase in PM2.5 after adjusting for risk factors. Risks were elevated in smokers and those with BMI greater than 30.
CONCLUSIONS: This study estimated significant elevated prevalent rate ratios per unit increase in PM2.5 in nine of the ten chronic diseases studied.
PMID: 25863281 [PubMed – as supplied by publisher]
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Poverty, Not Air Pollution Causing Childhood Asthma, Study Finds
The Heartland Institute A new study authored by a research team led by Dr. Corrine Keet of John's Hopkins Children's Center has found no link between outdoor air pollution and childhood asthma. Dr. Keet's team followed 23,000 U.S. children and found no statistically … |
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Pollution Poses Significant Issues for Asthma & Allergy Patients Part 2
HCPLive Along with the issues pollution poses for asthma and allergy patients, developing research shows it can also affect cardiovascular health as well. David B. Peden, MD, MS, from the University of North Carolina School of Medicine discussed these new … |
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